| Identification |
|---|
| HMDB Protein ID
| CDBP04067 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable Xaa-Pro aminopeptidase 3 |
| Description
| Not Available |
| Synonyms
|
- APP3
- Aminopeptidase P3
- X-Pro aminopeptidase 3
|
| Gene Name
| XPNPEP3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cellular process |
| Specific Function
| Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide |
| GO Classification
|
| Function |
| manganese ion binding |
| exopeptidase activity |
| aminopeptidase activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| hydrolase activity |
| transition metal ion binding |
| peptidase activity |
| peptidase activity, acting on l-amino acid peptides |
| Process |
| cellular process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 22q13.2 |
| SNPs
| XPNPEP3 |
| Gene Sequence
|
>1524 bp
ATGCCTTGGCTGCTCTCAGCCCCCAAGCTGGTTCCCGCTGTAGCAAACGTCCGCGGCCTC
TCAGGATGTATGTTGTGTTCACAGCGAAGGTACTCCCTTCAGCCTGTCCCAGAAAGGAGG
ATTCCAAACCGATACTTAGGCCAGCCCAGCCCCTTTACACACCCACACCTCCTCAGACCA
GGGGAGGTAACTCCAGGACTATCTCAGGTGGAATATGCACTTCGCAGACACAAACTAATG
TCTCTGATCCAGAAGGAAGCTCAAGGGCAGAGTGGGACAGACCAGACAGTGGTTGTGCTC
TCCAACCCTACATACTACATGAGCAACGATATTCCCTATACTTTCCACCAAGACAACAAT
TTCCTGTACCTATGTGGATTCCAAGAGCCTGATAGCATTCTTGTCCTTCAGAGCCTCCCT
GGCAAACAATTACCATCACACAAAGCCATACTTTTTGTGCCTCGGCGAGATCCCAGTCGA
GAACTTTGGGATGGTCCGCGATCTGGCACTGATGGAGCAATAGCTCTAACTGGAGTAGAC
GAAGCCTATACGCTAGAAGAATTTCAACATCTTCTACCAAAAATGAAAGCTGAGACGAAC
ATGGTTTGGTATGACTGGATGAGGCCCTCACATGCACAGCTTCACTCTGACTATATGCAG
CCCCTGACTGAGGCCAAAGCCAAGAGCAAGAACAAGGTTCGGGGTGTTCAGCAGCTGATA
CAGCGCCTCCGGCTGATCAAGTCTCCTGCAGAAATTGAACGAATGCAGATTGCTGGGAAG
CTGACATCACAGGCTTTCATAGAAACCATGTTCACCAGTAAAGCCCCTGTGGAAGAAGCC
TTTCTTTATGCTAAGTTTGAATTTGAATGCCGGGCTCGTGGCGCAGACATTTTAGCCTAT
CCACCTGTGGTGGCTGGTGGTAATCGGTCAAACACTTTGCACTATGTGAAAAATAATCAA
CTCATCAAGGATGGGGAAATGGTGCTTCTGGATGGAGGTTGTGAGTCTTCCTGCTATGCG
AGTGACATCACACGTACGTGGCCAGTCAATGGCAGGTTCACCGCACCTCAGGCAGAACTC
TATGAAGCCGTTCTAGAGATCCAAAGAGATTGTTTGGCCCTCTGCTTCCCTGGGACAAGC
TTGGAGAACATCTACAGCATGATGCTGACCCTGATAGGACAGAAGCTTAAAGACTTGGGG
ATCATGAAGAACATTAAGGAAAATAATGCCTTCAAGGCTGCTCGAAAATACTGTCCTCAT
CATGTTGGCCACTACCTCGGGATGGATGTCCATGACACTCCAGACATGCCCCGTTCCCTC
CCTCTGCAGCCTGGGATGGTAATCACAATTGAGCCCGGCATTTATATTCCAGAGGATGAC
AAAGATGCCCCAGAGAAGTTTCGGGGTCTTGGTGTACGAATTGAGGATGATGTAGTGGTG
ACTCAGGACTCACCTCTCATCCTTTCTGCAGACTGTCCCAAAGAGATGAATGACATTGAA
CAGATATGCAGCCAGGCTTCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 507 |
| Molecular Weight
| 57033.1 |
| Theoretical pI
| 6.83 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Probable Xaa-Pro aminopeptidase 3
MPWLLSAPKLVPAVANVRGLSGCMLCSQRRYSLQPVPERRIPNRYLGQPSPFTHPHLLRP
GEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLSNPTYYMSNDIPYTFHQDNN
FLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPSRELWDGPRSGTDGAIALTGVD
EAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLI
QRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAY
PPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAEL
YEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKAARKYCPH
HVGHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVV
TQDSPLILSADCPKEMNDIEQICSQAS
|
| External Links |
|---|
| GenBank ID Protein
| 48146909 |
| UniProtKB/Swiss-Prot ID
| Q9NQH7 |
| UniProtKB/Swiss-Prot Entry Name
| XPP3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| CR457396 |
| GeneCard ID
| XPNPEP3 |
| GenAtlas ID
| XPNPEP3 |
| HGNC ID
| HGNC:28052 |
| References |
|---|
| General References
| Not Available |