Identification
HMDB Protein ID CDBP04067
Secondary Accession Numbers Not Available
Name Probable Xaa-Pro aminopeptidase 3
Description Not Available
Synonyms
  1. APP3
  2. Aminopeptidase P3
  3. X-Pro aminopeptidase 3
Gene Name XPNPEP3
Protein Type Enzyme
Biological Properties
General Function Involved in cellular process
Specific Function Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide
GO Classification
Function
manganese ion binding
exopeptidase activity
aminopeptidase activity
ion binding
cation binding
metal ion binding
binding
catalytic activity
hydrolase activity
transition metal ion binding
peptidase activity
peptidase activity, acting on l-amino acid peptides
Process
cellular process
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 22q13.2
SNPs XPNPEP3
Gene Sequence
>1524 bp
ATGCCTTGGCTGCTCTCAGCCCCCAAGCTGGTTCCCGCTGTAGCAAACGTCCGCGGCCTC
TCAGGATGTATGTTGTGTTCACAGCGAAGGTACTCCCTTCAGCCTGTCCCAGAAAGGAGG
ATTCCAAACCGATACTTAGGCCAGCCCAGCCCCTTTACACACCCACACCTCCTCAGACCA
GGGGAGGTAACTCCAGGACTATCTCAGGTGGAATATGCACTTCGCAGACACAAACTAATG
TCTCTGATCCAGAAGGAAGCTCAAGGGCAGAGTGGGACAGACCAGACAGTGGTTGTGCTC
TCCAACCCTACATACTACATGAGCAACGATATTCCCTATACTTTCCACCAAGACAACAAT
TTCCTGTACCTATGTGGATTCCAAGAGCCTGATAGCATTCTTGTCCTTCAGAGCCTCCCT
GGCAAACAATTACCATCACACAAAGCCATACTTTTTGTGCCTCGGCGAGATCCCAGTCGA
GAACTTTGGGATGGTCCGCGATCTGGCACTGATGGAGCAATAGCTCTAACTGGAGTAGAC
GAAGCCTATACGCTAGAAGAATTTCAACATCTTCTACCAAAAATGAAAGCTGAGACGAAC
ATGGTTTGGTATGACTGGATGAGGCCCTCACATGCACAGCTTCACTCTGACTATATGCAG
CCCCTGACTGAGGCCAAAGCCAAGAGCAAGAACAAGGTTCGGGGTGTTCAGCAGCTGATA
CAGCGCCTCCGGCTGATCAAGTCTCCTGCAGAAATTGAACGAATGCAGATTGCTGGGAAG
CTGACATCACAGGCTTTCATAGAAACCATGTTCACCAGTAAAGCCCCTGTGGAAGAAGCC
TTTCTTTATGCTAAGTTTGAATTTGAATGCCGGGCTCGTGGCGCAGACATTTTAGCCTAT
CCACCTGTGGTGGCTGGTGGTAATCGGTCAAACACTTTGCACTATGTGAAAAATAATCAA
CTCATCAAGGATGGGGAAATGGTGCTTCTGGATGGAGGTTGTGAGTCTTCCTGCTATGCG
AGTGACATCACACGTACGTGGCCAGTCAATGGCAGGTTCACCGCACCTCAGGCAGAACTC
TATGAAGCCGTTCTAGAGATCCAAAGAGATTGTTTGGCCCTCTGCTTCCCTGGGACAAGC
TTGGAGAACATCTACAGCATGATGCTGACCCTGATAGGACAGAAGCTTAAAGACTTGGGG
ATCATGAAGAACATTAAGGAAAATAATGCCTTCAAGGCTGCTCGAAAATACTGTCCTCAT
CATGTTGGCCACTACCTCGGGATGGATGTCCATGACACTCCAGACATGCCCCGTTCCCTC
CCTCTGCAGCCTGGGATGGTAATCACAATTGAGCCCGGCATTTATATTCCAGAGGATGAC
AAAGATGCCCCAGAGAAGTTTCGGGGTCTTGGTGTACGAATTGAGGATGATGTAGTGGTG
ACTCAGGACTCACCTCTCATCCTTTCTGCAGACTGTCCCAAAGAGATGAATGACATTGAA
CAGATATGCAGCCAGGCTTCTTAA
Protein Properties
Number of Residues 507
Molecular Weight 57033.1
Theoretical pI 6.83
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Probable Xaa-Pro aminopeptidase 3
MPWLLSAPKLVPAVANVRGLSGCMLCSQRRYSLQPVPERRIPNRYLGQPSPFTHPHLLRP
GEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLSNPTYYMSNDIPYTFHQDNN
FLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPSRELWDGPRSGTDGAIALTGVD
EAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLI
QRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAY
PPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAEL
YEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKAARKYCPH
HVGHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVV
TQDSPLILSADCPKEMNDIEQICSQAS
GenBank ID Protein 48146909
UniProtKB/Swiss-Prot ID Q9NQH7
UniProtKB/Swiss-Prot Entry Name XPP3_HUMAN
PDB IDs Not Available
GenBank Gene ID CR457396
GeneCard ID XPNPEP3
GenAtlas ID XPNPEP3
HGNC ID HGNC:28052
References
General References Not Available