| Identification |
|---|
| HMDB Protein ID
| CDBP04057 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable aminopeptidase NPEPL1 |
| Description
| Not Available |
| Synonyms
|
- Aminopeptidase-like 1
|
| Gene Name
| NPEPL1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in aminopeptidase activity |
| Specific Function
| Probably catalyzes the removal of unsubstituted N- terminal amino acids from various peptides |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| exopeptidase activity |
| aminopeptidase activity |
| catalytic activity |
| hydrolase activity |
| peptidase activity |
| peptidase activity, acting on l-amino acid peptides |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein metabolic process |
| proteolysis |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20q13.32 |
| SNPs
| NPEPL1 |
| Gene Sequence
|
>1572 bp
ATGGCGAACGTGGGGCTGCAGTTCCAGGCGAGCGCGGGGGACTCGGACCCACAGAGCCGG
CCCCTGCTGCTGCTCGGGCAGCTGCACCACCTGCACCGCGTGCCCTGGAGCCACGTCCGC
GGGAAGCTGCAGCCCCGGGTCACCGAGGAGCTCTGGCAGGCTGCCCTGAGCACGCTCAAC
CCCAACCCCACGGACAGCTGTCCCCTCTACCTGAACTACGCCACCGTGGCTGCCCTGCCC
TGCAGGGTGAGCCGGCACAACAGCCCCTCGGCCGCCCACTTCATCACGCGGCTGGTGCGG
ACCTGCCTGCCGCCCGGAGCGCATCGCTGCATTGTGATGGTCTGCGAGCAGCCGGAGGTC
TTTGCTTCCGCCTGTGCCCTGGCCCGGGCCTTCCCGCTGTTCACCCACCGCTCAGGTGCC
TCTCGGCGCTTGGAGAAGAAGACGGTCACCGTGGAGTTTTTCCTGGTGGGACAAGACAAC
GGGCCGGTGGAGGTGTCCACATTGCAGTGCTTAGCGAATGCCACAGACGGCGTGCGGCTA
GCAGCCCGCATCGTGGACACACCCTGCAATGAGATGAACACCGACACCTTCCTCGAGGAG
ATTAACAAAGTTGGAAAGGAGCTGGGGATCATCCCAACCATCATCCGGGATGAGGAACTG
AAGACGAGAGGATTTGGAGGAATCTATGGGGTTGGCAAAGCCGCCCTGCATCCCCCAGCC
CTGGCCGTCCTCAGCCACACCCCAGATGGAGCCACGCAGACCATCGCCTGGGTGGGCAAA
GGCATCGTCTATGACACTGGAGGCCTCAGCATCAAAGGGAAGACTACCATGCCGGGGATG
AAGCGAGACTGCGGGGGTGCTGCGGCCGTCCTGGGGGCCTTCAGAGCCGCAATCAAGCAG
GGTTTCAAAGACAACCTCCACGCTGTGTTCTGCTTGGCTGAGAACTCGGTGGGGCCCAAT
GCGACAAGGCCAGATGACATCCACCTGCTGTACTCAGGGAAGACGGTGGAAATCAACAAC
ACGGATGCCGAGGGCAGGCTGGTGCTGGCAGATGGCGTGTCCTATGCTTGCAAGGACCTG
GGGGCCGACATCATCCTGGACATGGCCACCCTGACCGGGGCTCAGGGCATTGCCACAGGG
AAGTACCACGCCGCGGTGCTCACCAACAGCGCTGAGTGGGAGGCCGCCTGTGTGAAGGCG
GGCAGGAAGTGTGGGGACCTGGTGCACCCGCTGGTCTACTGCCCCGAGCTGCACTTCAGC
GAGTTCACCTCAGCTGTGGCGGACATGAAGAACTCAGTGGCGGACCGAGACAACAGCCCC
AGCTCCTGTGCTGGCCTCTTCATCGCCTCACACATCGGCTTCGACTGGCCCGGAGTCTGG
GTCCACCTGGACATTGCTGCACCGGTGCATGCTGGTGAGCGAGCCACAGGCTTCGGTGTG
GCCCTCCTGCTGGCGCTCTTCGGCCGTGCCTCTGAGGACCCTCTGCTGAACCTGGTGTCC
CCACTGGGCTGTGAGGTGGATGTCGAGGAGGGGGACCTGGGGAGGGACTCCAAGAGACGC
AGGCTTGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 523 |
| Molecular Weight
| 55860.3 |
| Theoretical pI
| 6.88 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Probable aminopeptidase NPEPL1
MANVGLQFQASAGDSDPQSRPLLLLGQLHHLHRVPWSHVRGKLQPRVTEELWQAALSTLN
PNPTDSCPLYLNYATVAALPCRVSRHNSPSAAHFITRLVRTCLPPGAHRCIVMVCEQPEV
FASACALARAFPLFTHRSGASRRLEKKTVTVEFFLVGQDNGPVEVSTLQCLANATDGVRL
AARIVDTPCNEMNTDTFLEEINKVGKELGIIPTIIRDEELKTRGFGGIYGVGKAALHPPA
LAVLSHTPDGATQTIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGAAAVLGAFRAAIKQ
GFKDNLHAVFCLAENSVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADGVSYACKDL
GADIILDMATLTGAQGIATGKYHAAVLTNSAEWEAACVKAGRKCGDLVHPLVYCPELHFS
EFTSAVADMKNSVADRDNSPSSCAGLFIASHIGFDWPGVWVHLDIAAPVHAGERATGFGV
ALLLALFGRASEDPLLNLVSPLGCEVDVEEGDLGRDSKRRRLV
|
| External Links |
|---|
| GenBank ID Protein
| 47155554 |
| UniProtKB/Swiss-Prot ID
| Q8NDH3 |
| UniProtKB/Swiss-Prot Entry Name
| PEPL1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_024663.3 |
| GeneCard ID
| NPEPL1 |
| GenAtlas ID
| NPEPL1 |
| HGNC ID
| HGNC:16244 |
| References |
|---|
| General References
| Not Available |