Identification
HMDB Protein ID CDBP04045
Secondary Accession Numbers Not Available
Name Beta-1,3-galactosyltransferase 1
Description Not Available
Synonyms
  1. Beta-1,3-GalTase 1
  2. Beta3Gal-T1
  3. Beta3GalT1
  4. UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1
Gene Name B3GALT1
Protein Type Enzyme
Biological Properties
General Function Involved in galactosyltransferase activity
Specific Function Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N- acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues
GO Classification
Component
membrane
cell part
Function
galactosyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring hexosyl groups
transferase activity, transferring glycosyl groups
Process
metabolic process
macromolecule metabolic process
macromolecule modification
protein modification process
protein amino acid glycosylation
Cellular Location
  1. Golgi apparatus membrane
  2. Single-pass type II membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2q24.3
SNPs B3GALT1
Gene Sequence
>981 bp
ATGGCTTCAAAGGTCTCCTGTTTGTATGTTTTGACAGTTGTGTGCTGGGCCAGCGCTCTC
TGGTACTTGAGTATAACTCGCCCTACTTCTTCTTACACTGGCTCCAAACCATTCAGCCAC
CTAACAGTTGCCAGGAAAAACTTCACCTTTGGCAACATAAGAACTCGACCTATCAACCCA
CATTCTTTTGAATTTCTTATCAACGAGCCCAATAAATGTGAGAAAAACATTCCTTTTCTT
GTTATCCTCATCAGCACCACTCACAAGGAATTTGATGCCCGTCAGGCAATCAGAGAGACG
TGGGGGGATGAGAACAACTTTAAGGGGATCAAGATAGCCACCCTGTTCCTCCTGGGCAAG
AATGCTGATCCTGTTCTCAATCAGATGGTGGAGCAAGAGAGCCAAATCTTCCATGATATC
ATCGTGGAGGACTTTATTGACTCCTACCATAACCTTACCCTCAAAACATTAATGGGGATG
AGATGGGTGGCCACTTTTTGTTCAAAAGCCAAGTATGTCATGAAAACAGACAGCGACATT
TTTGTAAACATGGACAATCTTATTTATAAATTACTGAAACCCTCCACCAAGCCACGAAGA
AGGTATTTTACTGGCTATGTCATTAATGGAGGACCGATTCGGGATGTCCGCAGTAAGTGG
TATATGCCCAGGGATTTGTACCCAGACAGTAACTACCCACCTTTCTGTTCGGGGACTGGC
TACATCTTTTCAGCCGATGTAGCTGAACTCATTTACAAGACCTCACTCCACACAAGGCTG
CTTCACCTTGAAGACGTATATGTGGGACTGTGTCTTCGAAAGCTGGGCATACATCCTTTC
CAGAACAGTGGCTTCAATCACTGGAAAATGGCCTACAGTTTGTGTAGGTATCGCCGAGTT
ATCACTGTGCATCAGATCTCTCCAGAAGAAATGCACAGAATCTGGAATGACATGTCAAGC
AAGAAACATCTCAGATGTTAG
Protein Properties
Number of Residues 326
Molecular Weight 37992.7
Theoretical pI 9.65
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["7-26"]
Protein Sequence
>Beta-1,3-galactosyltransferase 1
MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINP
HSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGK
NADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDI
FVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTG
YIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRV
ITVHQISPEEMHRIWNDMSSKKHLRC
GenBank ID Protein 7593005
UniProtKB/Swiss-Prot ID Q9Y5Z6
UniProtKB/Swiss-Prot Entry Name B3GT1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB041407
GeneCard ID B3GALT1
GenAtlas ID B3GALT1
HGNC ID HGNC:916
References
General References Not Available