Identification |
HMDB Protein ID
| CDBP04045 |
Secondary Accession Numbers
| Not Available |
Name
| Beta-1,3-galactosyltransferase 1 |
Description
| Not Available |
Synonyms
|
- Beta-1,3-GalTase 1
- Beta3Gal-T1
- Beta3GalT1
- UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1
|
Gene Name
| B3GALT1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in galactosyltransferase activity |
Specific Function
| Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N- acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues |
GO Classification
|
Component |
membrane |
cell part |
Function |
galactosyltransferase activity |
catalytic activity |
transferase activity |
transferase activity, transferring hexosyl groups |
transferase activity, transferring glycosyl groups |
Process |
metabolic process |
macromolecule metabolic process |
macromolecule modification |
protein modification process |
protein amino acid glycosylation |
|
Cellular Location
|
- Golgi apparatus membrane
- Single-pass type II membrane protein (Probable)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 2q24.3 |
SNPs
| B3GALT1 |
Gene Sequence
|
>981 bp
ATGGCTTCAAAGGTCTCCTGTTTGTATGTTTTGACAGTTGTGTGCTGGGCCAGCGCTCTC
TGGTACTTGAGTATAACTCGCCCTACTTCTTCTTACACTGGCTCCAAACCATTCAGCCAC
CTAACAGTTGCCAGGAAAAACTTCACCTTTGGCAACATAAGAACTCGACCTATCAACCCA
CATTCTTTTGAATTTCTTATCAACGAGCCCAATAAATGTGAGAAAAACATTCCTTTTCTT
GTTATCCTCATCAGCACCACTCACAAGGAATTTGATGCCCGTCAGGCAATCAGAGAGACG
TGGGGGGATGAGAACAACTTTAAGGGGATCAAGATAGCCACCCTGTTCCTCCTGGGCAAG
AATGCTGATCCTGTTCTCAATCAGATGGTGGAGCAAGAGAGCCAAATCTTCCATGATATC
ATCGTGGAGGACTTTATTGACTCCTACCATAACCTTACCCTCAAAACATTAATGGGGATG
AGATGGGTGGCCACTTTTTGTTCAAAAGCCAAGTATGTCATGAAAACAGACAGCGACATT
TTTGTAAACATGGACAATCTTATTTATAAATTACTGAAACCCTCCACCAAGCCACGAAGA
AGGTATTTTACTGGCTATGTCATTAATGGAGGACCGATTCGGGATGTCCGCAGTAAGTGG
TATATGCCCAGGGATTTGTACCCAGACAGTAACTACCCACCTTTCTGTTCGGGGACTGGC
TACATCTTTTCAGCCGATGTAGCTGAACTCATTTACAAGACCTCACTCCACACAAGGCTG
CTTCACCTTGAAGACGTATATGTGGGACTGTGTCTTCGAAAGCTGGGCATACATCCTTTC
CAGAACAGTGGCTTCAATCACTGGAAAATGGCCTACAGTTTGTGTAGGTATCGCCGAGTT
ATCACTGTGCATCAGATCTCTCCAGAAGAAATGCACAGAATCTGGAATGACATGTCAAGC
AAGAAACATCTCAGATGTTAG
|
Protein Properties |
Number of Residues
| 326 |
Molecular Weight
| 37992.7 |
Theoretical pI
| 9.65 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Beta-1,3-galactosyltransferase 1
MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINP
HSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGK
NADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDI
FVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTG
YIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRV
ITVHQISPEEMHRIWNDMSSKKHLRC
|
External Links |
GenBank ID Protein
| 7593005 |
UniProtKB/Swiss-Prot ID
| Q9Y5Z6 |
UniProtKB/Swiss-Prot Entry Name
| B3GT1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB041407 |
GeneCard ID
| B3GALT1 |
GenAtlas ID
| B3GALT1 |
HGNC ID
| HGNC:916 |
References |
General References
| Not Available |