Identification |
HMDB Protein ID
| CDBP04035 |
Secondary Accession Numbers
| Not Available |
Name
| Serine/threonine-protein kinase TNNI3K |
Description
| Not Available |
Synonyms
|
- Cardiac ankyrin repeat kinase
- TNNI3-interacting kinase
|
Gene Name
| TNNI3K |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein kinase activity |
Specific Function
| May play a role in cardiac physiology |
GO Classification
|
Function |
protein kinase activity |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
Process |
phosphorus metabolic process |
phosphate metabolic process |
metabolic process |
cellular metabolic process |
protein amino acid phosphorylation |
phosphorylation |
|
Cellular Location
|
- Nucleus
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1p31.1 |
SNPs
| TNNI3K |
Gene Sequence
|
>2508 bp
ATGGGAAATTATAAATCTAGACCAACCCAAACTTGTACTGATGAATGGAAGAAAAAAGTC
AGTGAATCATATGTTATCACAATAGAAAGATTAGAAGATGACCTGCAGATCAAGGAAAAA
GAACTGACAGAACTAAGGAATATATTTGGCTCTGATGAAGCCTTCAGTAAAGTCAATTTA
AATTACCGCACTGAAAATGGGCTGTCTCTACTTCATTTATGTTGCATTTGTGGAGGCAAG
AAATCACATATTCGAACTCTTATGTTGAAAGGGCTCCGCCCATCTCGACTGACAAGAAAT
GGATTTACAGCCTTGCATTTAGCAGTTTACAAGGATAATGCAGAATTGATCACTTCTCTG
CTTCACAGTGGAGCTGATATACAGCAGGTTGGATACGGTGGCCTCACTGCCCTCCATATT
GCTACAATAGCTGGCCACCTAGAGGCTGCTGATGTGCTGTTGCAACATGGAGCTAATGTC
AATATTCAAGATGCAGTTTTTTTCACTCCATTGCATATTGCAGCGTACTATGGACATGAA
CAGGTAACTCGCCTTCTTTTGAAATTTGGTGCTGATGTAAATGTAAGTGGTGAAGTTGGA
GATAGACCCCTCCACCTAGCATCTGCAAAAGGATTCTTGAATATTGCAAAACTCTTGATG
GAAGAAGGCAGCAAAGCAGATGTGAATGCTCAAGATAATGAAGACCATGTCCCACTCCAT
TTCTGTTCTCGATTTGGACACCATGATATAGTTAAGTATCTGCTGCAAAGTGATTTGGAA
GTTCAACCTCATGTTGTTAATATCTATGGAGATACCCCCTTACACCTGGCATGCTACAAT
GGCAAATTTGAAGTTGCCAAGGAAATCATCCAAATATCAGGAACAGAAAGTCTGACTAAG
GAAAACATCTTCAGTGAAACAGCTTTTCATAGTGCTTGTACCTATGGCAAGAGCATTGAC
CTAGTCAAATTTCTTCTTGATCAGAATGTCATAAACATCAACCACCAAGGAAGGGATGGG
CACACTGGATTACACTCTGCTTGCTACCACGGTCACATTCGCCTGGTTCAGTTCTTACTG
GATAATGGAGCTGATATGAATCTAGTGGCTTGTGATCCCAGCAGGTCTAGTGGTGAAAAA
GATGAGCAGACATGTTTGATGTGGGCTTATGAAAAAGGGCATGATGCCATTGTCACACTC
CTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATTCTCAGCCTGGA
GGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAA
GAGAAGGCAGATATTCTCCTCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTC
TCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAGTATATAAAGGA
CGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAG
TCAGATGTGGATATGTTTTGCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGC
GTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCATTGTCACTCAA
TACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTG
CAGTCTAAATTAATTATTGCAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTG
ACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCTATGAGGATGGG
CATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAAC
ATGACAAAACAACCTGGGAACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACT
CGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGGAAATTCTCACT
GGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCAC
CACATCAGACCTCCCATTGGCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGA
GGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCATGAAGTTAGAA
GAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTC
TCACCTTCTTCTTCTTCTGATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTG
GCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGTCCTATGCTGCT
TTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGA
AGTCTTCAATACACACCCATTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATG
CATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGA
|
Protein Properties |
Number of Residues
| 835 |
Molecular Weight
| 92849.7 |
Theoretical pI
| 6.74 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Serine/threonine-protein kinase TNNI3K
MGNYKSRPTQTCTDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNL
NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL
LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE
QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLH
FCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTK
ENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLL
DNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPG
GDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKG
RCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQ
YISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDG
HAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILT
GEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLE
ECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNARSYAA
LSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHFHSCRNSSSFEDSS
|
External Links |
GenBank ID Protein
| 4768829 |
UniProtKB/Swiss-Prot ID
| Q59H18 |
UniProtKB/Swiss-Prot Entry Name
| TNI3K_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF116826 |
GeneCard ID
| TNNI3K |
GenAtlas ID
| TNNI3K |
HGNC ID
| HGNC:19661 |
References |
General References
| Not Available |