Identification |
HMDB Protein ID
| CDBP04015 |
Secondary Accession Numbers
| Not Available |
Name
| Rho-related GTP-binding protein RhoV |
Description
| Not Available |
Synonyms
|
- CDC42-like GTPase 2
- GTP-binding protein-like 2
- Rho GTPase-like protein ARHV
- WRCH-2
- Wnt-1 responsive Cdc42 homolog 2
|
Gene Name
| RHOV |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTP binding |
Specific Function
| Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway |
GO Classification
|
Component |
intracellular |
cell part |
Function |
purine nucleotide binding |
binding |
nucleotide binding |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
Process |
biological regulation |
regulation of biological process |
regulation of cellular process |
signal transduction |
intracellular signal transduction |
small gtpase mediated signal transduction |
|
Cellular Location
|
- Cell membrane
- Lipid-anchor
- Lipid-anchor
- Endosome membrane
- Cytoplasmic side
- Cytoplasmic side
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 15q13.3 |
SNPs
| RHOV |
Gene Sequence
|
>711 bp
ATGCCGCCGCGGGAGCTGAGCGAGGCCGAGCCGCCCCCGCTCCGGGCCCCGACCCCTCCC
CCGCGGCGGCGTAGCGCGCCCCCAGAGCTGGGCATCAAGTGCGTGCTGGTGGGCGACGGC
GCCGTGGGCAAGAGCAGCCTCATCGTCAGCTACACCTGCAATGGGTACCCCGCGCGCTAC
CGGCCCACTGCGCTGGACACCTTCTCTGTGCAAGTCCTGGTGGATGGAGCTCCGGTGCGC
ATTGAGCTCTGGGACACAGCGGGACAGGAGGATTTTGACCGACTTCGTTCCCTTTGCTAC
CCGGATACCGATGTCTTCCTGGCGTGCTTCAGCGTGGTGCAGCCCAGCTCCTTTCAAAAC
ATCACAGAGAAATGGCTGCCCGAGATCCGCACGCACAACCCCCAGGCGCCTGTGCTGCTG
GTGGGCACCCAGGCCGACCTGAGGGACGATGTCAACGTACTAATTCAGCTGGACCAGGGG
GGCCGGGAGGGCCCCGTGCCCCAACCCCAGGCTCAGGGTCTGGCCGAGAGGATCCGAGCC
TGCTGCTACCTTGAGTGCTCAGCCTTGACGCAGAAGAACTTGAAGGAAGTATTTGACTCG
GCTATTCTCAGTGCCATTGAGCACAAAGCCCGGCTGGAGAAGAAACTGAATGCCAAAGGT
GTGCGCACCCTCTCCCGCTGCCGCTGGAAGAAGTTCTTCTGCTTCGTTTGA
|
Protein Properties |
Number of Residues
| 236 |
Molecular Weight
| 26216.9 |
Theoretical pI
| 8.14 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Rho-related GTP-binding protein RhoV
MPPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARY
RPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQN
ITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRA
CCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
|
External Links |
GenBank ID Protein
| 19570848 |
UniProtKB/Swiss-Prot ID
| Q96L33 |
UniProtKB/Swiss-Prot Entry Name
| RHOV_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB079131 |
GeneCard ID
| RHOV |
GenAtlas ID
| RHOV |
HGNC ID
| HGNC:18313 |
References |
General References
| Not Available |