Cannabis Compound Database: Showing Protein ATP-dependent DNA helicase Q1 (CDBP04014)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP04014

Secondary Accession Numbers

Not Available

Name

ATP-dependent DNA helicase Q1

Description

Not Available

Synonyms

DNA helicase, RecQ-like type 1
DNA-dependent ATPase Q1
RecQ protein-like 1
RecQ1

Gene Name

RECQL

Protein Type

Enzyme

Biological Properties

General Function

Involved in nucleic acid binding

Specific Function

DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.

GO Classification

Biological Process
DNA repair
DNA replication
DNA strand renaturation
DNA recombination
Cellular Component
microtubule cytoskeleton
nucleus
Function
atp binding
atp-dependent helicase activity
dna helicase activity
atp-dependent dna helicase activity
atpase activity
atpase activity, coupled
nucleic acid binding
atp-dependent 3'-5' dna helicase activity
nucleoside-triphosphatase activity
binding
helicase activity
catalytic activity
hydrolase activity, acting on acid anhydrides
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
nucleoside binding
pyrophosphatase activity
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
Molecular Function
DNA binding
ATP-dependent 3'-5' DNA helicase activity
ATP binding
ATP-dependent DNA helicase activity
Process
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
dna metabolic process
dna replication
dna recombination
dna repair

Cellular Location

Nucleus

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

12p12

SNPs

RECQL

Gene Sequence

>1950 bp
ATGGCGTCCGTTTCAGCTCTAACTGAGGAACTGGATTCTATAACCAGTGAGCTACATGCA
GTAGAAATTCAAATTCAAGAACTTACGGAAAGGCAACAAGAGCTTATTCAGAAAAAAAAA
GTCCTGACAAAGAAAATAAAGCAGTGTTTAGAGGATTCTGATGCCGGGGCAAGCAATGAA
TATGATTCTTCACCTGCCGCTTGGAATAAAGAAGATTTTCCATGGTCTGGTAAAGTTAAA
GATATTCTGCAAAATGTCTTTAAACTGGAAAAGTTCAGACCACTTCAGCTTGAAACTATT
AACGTAACAATGGCTGGAAAGGAGGTATTTCTTGTTATGCCTACAGGAGGTGGAAAGAGC
TTATGTTACCAGTTACCAGCATTATGTTCAGATGGTTTTACACTCGTCATTTGCCCATTG
ATCTCTCTTATGGAAGACCAATTAATGGTTTTAAAACAATTAGGAATTTCAGCAACCATG
TTAAATGCTTCTAGTTCTAAGGAGCATGTTAAATGGGTTCATGCTGAAATGGTAAATAAA
AACTCCGAGTTAAAGCTGATTTATGTGACTCCAGAGAAAATTGCAAAAAGCAAAATGTTT
ATGTCAAGACTAGAGAAAGCCTATGAAGCAAGGAGATTTACTCGAATTGCTGTGGATGAA
GTTCACTGCTGTAGTCAGTGGGGACATGATTTCAGACCTGATTATAAGGCACTTGGTATC
TTAAAGCGGCAGTTCCCTAACGCATCACTAATTGGGCTGACTGCAACTGCAACAAATCAC
GTTTTGACGGATGCTCAGAAAATTTTGTGCATTGAAAAGTGTTTTACTTTTACAGCTTCT
TTTAATAGGCCAAATCTATATTATGAGGTTCGGCAGAAGCCCTCAAACACTGAAGATTTT
ATTGAGGATATTGTAAAGCTCATTAATGGGAGATACAAAGGGCAATCAGGAATCATATAT
TGTTTTTCTCAGAAAGACTCTGAACAAGTTACGGTTAGTTTGCAGAATCTGGGAATTCAT
GCAGGTGCTTACCATGCCAATTTGGAGCCAGAAGATAAGACCACAGTTCATAGAAAATGG
TCAGCCAATGAAATTCAGGTAGTAGTGGCAACTGTTGCATTTGGTATGGGAATTGATAAG
CCAGATGTGAGGTTTGTTATCCATCATTCAATGAGTAAATCCATGGAAAATTATTACCAA
GAGAGTGGACGTGCAGGTCGAGATGACATGAAAGCAGACTGTATTTTGTACTACGGCTTT
GGAGATATATTCAGAATAAGTTCAATGGTGGTGATGGAAAATGTGGGACAGCAGAAGCTT
TATGAGATGGTATCATACTGTCAAAACATAAGCAAATGTCGTCGTGTGTTGATGGCTCAA
CATTTTGATGAAGTATGGAACTCAGAAGCATGTAACAAAATGTGCGATAACTGCTGTAAA
GACAGTGCATTTGAAAGAAAGAACATAACAGAGTACTGCAGAGATCTAATCAAGATCCTG
AAGCAGGCAGAGGAACTGAATGAAAAACTCACTCCATTGAAACTGATTGATTCTTGGATG
GGAAAGGGTGCAGCAAAACTGAGAGTAGCAGGTGTTGTGGCTCCCACACTTCCTCGTGAA
GATCTGGAGAAGATTATTGCACACTTTCTAATACAGCAGTATCTTAAAGAAGACTACAGT
TTTACAGCTTATGCTACCATTTCGTATTTGAAAATAGGACCTAAAGCTAATCTTCTGAAC
AATGAGGCACATGCTATTACTATGCAAGTGACAAAGTCCACGCAGAACTCTTTCAGGGCT
GAATCGTCTCAAACTTGTCATTCTGAACAAGGTGATAAAAAGATGGAGGAAAAAAATTCA
GGCAACTTCCAGAAGAAGGCTGCAAACATGCTTCAGCAATCTGGTTCTAAGAATACAGGA
GCTAAGAAAAGAAAAATCGATGATGCCTGA

Protein Properties

Number of Residues

649

Molecular Weight

73456.78

Theoretical pI

7.89

Pfam Domain Function

Helicase_C; (PF00271 )
DEAD; (PF00270 )
RQC (PF09382 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>ATP-dependent DNA helicase Q1
MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA

External Links

GenBank ID Protein

14591904

UniProtKB/Swiss-Prot ID

P46063

UniProtKB/Swiss-Prot Entry Name

RECQ1_HUMAN

PDB IDs