Showing Protein Nuclear inhibitor of protein phosphatase 1 (CDBP04000)
| Identification | |
|---|---|
| HMDB Protein ID | CDBP04000 |
| Secondary Accession Numbers | Not Available |
| Name | Nuclear inhibitor of protein phosphatase 1 |
| Description | Not Available |
| Synonyms |
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| Gene Name | PPP1R8 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in DNA binding |
| Specific Function | Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing |
| GO Classification | Not Available |
| Cellular Location |
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| Pathways | Not Available |
| Gene Properties | |
| Chromosome Location | Chromosome:1 |
| Locus | 1p35 |
| SNPs | PPP1R8 |
| Gene Sequence |
>1056 bp ATGGCGGCAGCCGCGAACTCCGGCTCTAGCCTCCCGCTGTTCGACTGCCCAACCTGGGCA GGTAAGCCCCCTCCCGGTTTACATCTGGATGTAGTCAAAGGAGACAAACTAATTGAGAAA CTGATTATTGATGAGAAGAAGTATTACTTATTTGGGAGAAACCCTGATTTGTGTGACTTT ACCATTGACCACCAGTCTTGCTCTCGGGTCCATGCTGCACTTGTCTACCACAAGCATCTG AAGAGAGTTTTCCTGATAGATCTCAACAGTACACACGGCACTTTCTTGGGTCACATTCGG TTGGAACCTCACAAGCCTCAGCAAATTCCCATCGATTCCACGGTCTCATTTGGCGCATCC ACAAGGGCATACACTCTGCGCGAGAAGCCTCAGACATTGCCATCGGCTGTGAAAGGAGAT GAGAAGATGGGTGGAGAGGATGATGAACTCAAGGGCTTACTGGGGCTTCCAGAGGAGGAA ACTGAGCTTGATAACCTGACAGAGTTCAACACTGCCCACAACAAGCGGATTTCTACCCTT ACCATTGAGGAGGGAAATCTGGACATTCAAAGACCAAAGAGGAAGAGGAAGAACTCACGG GTGACATTCAGTGAGGATGATGAGATCATCAACCCAGAGGATGTGGATCCCTCAGTTGGT CGATTCAGGAACATGGTGCAAACTGCAGTGGTCCCAGTCAAGAAGAAGCGTGTGGAGGGC CCTGGCTCCCTGGGCCTGGAGGAATCAGGGAGCAGGCGCATGCAGAACTTTGCCTTCAGC GGAGGACTCTACGGGGGCCTGCCCCCCACACACAGTGAAGCAGGCTCCCAGCCACATGGC ATCCATGGGACAGCACTCATCGGTGGCTTGCCCATGCCATACCCAAACCTTGCCCCTGAT GTGGACTTGACTCCTGTTGTGCCGTCAGCAGTGAACATGAACCCTGCACCAAACCCTGCA GTCTATAACCCTGAAGCTGTAAATGAACCCAAGAAGAAGAAATATGCAAAAGAGGCTTGG CCAGGCAAGAAGCCCACACCTTCCTTGCTGATTTGA |
| Protein Properties | |
| Number of Residues | 351 |
| Molecular Weight | 38478.5 |
| Theoretical pI | 7.42 |
| Pfam Domain Function |
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| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Nuclear inhibitor of protein phosphatase 1 MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDF TIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGAS TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEG PGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPD VDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI |
| External Links | |
| GenBank ID Protein | 4883485 |
| UniProtKB/Swiss-Prot ID | Q12972 |
| UniProtKB/Swiss-Prot Entry Name | PP1R8_HUMAN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF061958 |
| GeneCard ID | PPP1R8 |
| GenAtlas ID | PPP1R8 |
| HGNC ID | HGNC:9296 |
| References | |
| General References | Not Available |