Identification |
HMDB Protein ID
| CDBP03979 |
Secondary Accession Numbers
| Not Available |
Name
| Serine/threonine-protein kinase Nek5 |
Description
| Not Available |
Synonyms
|
- Never in mitosis A-related kinase 5
- NimA-related protein kinase 5
|
Gene Name
| NEK5 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein kinase activity |
Specific Function
| ATP + a protein = ADP + a phosphoprotein |
GO Classification
|
Function |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
protein kinase activity |
protein serine/threonine kinase activity |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
Process |
phosphorus metabolic process |
phosphate metabolic process |
metabolic process |
cellular metabolic process |
protein amino acid phosphorylation |
phosphorylation |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 13q14.3 |
SNPs
| NEK5 |
Gene Sequence
|
>2127 bp
ATGGATAAGTACGATGTGATTAAGGCCATCGGGCAAGGTGCCTTCGGGAAAGCATACTTA
GCTAAAGGGAAATCAGATAGCAAGCACTGTGTCATAAAAGAGATCAATTTTGAAAAGATG
CCCATACAAGAAAAAGAAGCTTCAAAGAAAGAAGTGATTCTTCTGGAAAAGATGAAACAT
CCCAACATTGTAGCCTTCTTCAATTCATTTCAAGAGAATGGCAGGCTGTTTATTGTAATG
GAATATTGTGATGGAGGGGATCTCATGAAAAGGATCAATAGACAACGGGGTGTGTTATTT
AGTGAAGATCAGATCCTCGGTTGGTTTGTACAGATTTCTCTAGGACTAAAACATATTCAT
GACAGGAAGATATTACACAGGGACATAAAAGCTCAGAACATTTTTCTTAGCAAGAACGGA
ATGGTGGCAAAGCTTGGGGACTTTGGTATAGCAAGAGTCCTGAATAATTCCATGGAACTT
GCTCGAACTTGTATTGGAACACCTTACTACCTGTCCCCAGAGATCTGTCAGAATAAACCC
TACAACAATAAAACGGATATTTGGTCTCTTGGCTGTGTCTTATATGAGCTCTGCACACTT
AAACATCCTTTTGAGGGTAACAACTTACAGCAGCTGGTTCTGAAGATTTGTCAAGCACAT
TTTGCCCCAATATCTCCGGGGTTTTCTCGTGAGCTCCATTCCTTGATATCTCAGCTCTTT
CAAGTATCTCCTCGAGACCGACCATCCATAAATTCCATTTTGAAAAGGCCCTTTTTAGAG
AATCTTATTCCCAAATATTTGACTCCTGAGGTCATTCAGGAAGAATTCAGTCACATGCTT
ATATGCAGAGCAGGAGCGCCAGCTTCTCGACATGCTGGGAAGGTGGTCCAGAAGTGTAAA
ATACAAAAAGTGAGATTCCAGGGAAAGTGCCCACCAAGATCAAGGATATCTGTGCCAATT
AAAAGGAATGCTATATTGCATAGAAATGAATGGAGACCACCAGCTGGAGCCCAGAAGGCC
AGATCTATAAAAATGATAGAAAGACCCAAAATTGCTGCTGTCTGTGGACATTATGATTAT
TATTATGCTCAACTTGATATGCTGAGGAGGAGAGCCCACAAACCAAGTTATCACCCTATT
CCTCAAGAAAATACTGGAGTTGAGGATTACGGTCAGGAAACGAGGCATGGTCCATCCCCA
AGTCAATGGCCTGCTGAGTACCTTCAGAGAAAATTTGAAGCTCAACAATATAAGTTGAAA
GTGGAGAAGCAATTGGGTCTTCGTCCATCTTCTGCCGAGCCAAATTACAACCAGAGACAA
GAGCTAAGAAGTAATGGAGAAGAGCCTAGATTCCAGGAGCTGCCATTTAGGAAAAACGAA
ATGAAGGAACAGGAATATTGGAAGCAGTTAGAGGAAATACGCCAACAGTACCACAATGAC
ATGAAAGAAATTAGAAAGAAGATGGGGAGAGAACCAGAGGAGAACTCAAAAATAAGTCAT
AAAACCTATTTGGTGAAGAAGAGTAACCTGCCTGTCCATCAAGATGCATCTGAGGGAGAA
GCACCTGTGCAGATGGAATTTCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCT
TGGCTCACCGCAACCTCCGCCTCCCAGGACATTGAAAAAGACTTGAAACAAATGAGGCTT
CAGAACACAAAGGAAAGTAAAAATCCAGAACAGAAATATAAAGCTAAGAAGGGGGTAAAA
TTTGAAATTAATTTAGACAAATGTATTTCTGATGAAAACATCCTCCAAGAGGAAGAGGCA
ATGGATATACCAAATGAAACTTTGACCTTTGAGGATGGCATGAAGTTTAAGGAATATGAA
TGTGTAAAGGAGCATGGAGATTATACAGACAAAGCATTTGAAAAACTTCACTGCCCAGAA
GCAGGGTTTTCCACGCAGACTGTAGCTGCTGTGGGAAACAGGAGGCAGTGGGATGGAGGA
GCGCCTCAGACTCTGCTGCAGATGATGGCAGTGGCCGACATCACCTCCACCTGCCCCACG
GGGCCTGACAGTGAGTCTGTGCTTAGCGTCAGTCGTCAGGAAGGGAAGACCAAGGACCCG
TACAGCCCAGTGCTCATCCTGATGTGA
|
Protein Properties |
Number of Residues
| 708 |
Molecular Weight
| 81444.9 |
Theoretical pI
| 9.18 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Serine/threonine-protein kinase Nek5
MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKH
PNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIH
DRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKP
YNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLF
QVSPRDRPSINSILKRPFLENLIPKYLTPEVIQEEFSHMLICRAGAPASRHAGKVVQKCK
IQKVRFQGKCPPRSRISVPIKRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDY
YYAQLDMLRRRAHKPSYHPIPQENTGVEDYGQETRHGPSPSQWPAEYLQRKFEAQQYKLK
VEKQLGLRPSSAEPNYNQRQELRSNGEEPRFQELPFRKNEMKEQEYWKQLEEIRQQYHND
MKEIRKKMGREPEENSKISHKTYLVKKSNLPVHQDASEGEAPVQMEFRSCCPGWSAMARS
WLTATSASQDIEKDLKQMRLQNTKESKNPEQKYKAKKGVKFEINLDKCISDENILQEEEA
MDIPNETLTFEDGMKFKEYECVKEHGDYTDKAFEKLHCPEAGFSTQTVAAVGNRRQWDGG
APQTLLQMMAVADITSTCPTGPDSESVLSVSRQEGKTKDPYSPVLILM
|
External Links |
GenBank ID Protein
| 123247885 |
UniProtKB/Swiss-Prot ID
| Q6P3R8 |
UniProtKB/Swiss-Prot Entry Name
| NEK5_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AL139082 |
GeneCard ID
| NEK5 |
GenAtlas ID
| NEK5 |
HGNC ID
| HGNC:7748 |
References |
General References
| Not Available |