Cannabis Compound Database: Showing Protein Forkhead box protein K2 (CDBP03935)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03935

Secondary Accession Numbers

Not Available

Name

Forkhead box protein K2

Description

Not Available

Synonyms

Cellular transcription factor ILF-1
FOXK1
Interleukin enhancer-binding factor 1

Gene Name

FOXK2

Protein Type

Transcription Factor

Biological Properties

General Function

Involved in sequence-specific DNA binding transcription factor activity

Specific Function

Recognizes the core sequence 5'-TAAACA-3'. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter. Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements

GO Classification

Component
membrane-bounded organelle
intracellular membrane-bounded organelle
nucleus
organelle
Function
binding
nucleic acid binding
dna binding
sequence-specific dna binding
sequence-specific dna binding transcription factor activity
Process
biological regulation
regulation of biological process
regulation of metabolic process
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
regulation of transcription, dna-dependent

Cellular Location

Nucleus (Probable)

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

17q25

SNPs

FOXK2

Gene Sequence

>1983 bp
ATGGCGGCGGCCGCGGCGGCGCTCTCGGGCGCGGGCACGCCACCCGCGGGCGGCGGGGCC
GGGGGCGGCGGGGCCGGGGGCGGCGGGTCCCCGCCGGGCGGCTGGGCCGTGGCGCGCCTG
GAGGGCCGCGAGTTCGAGTATCTGATGAAGAAGCGCTCGGTGACCATCGGCCGCAACTCG
TCGCAGGGCTCGGTGGACGTGAGCATGGGCCACTCGAGCTTCATCTCCCGGCGCCACCTC
GAGATCTTCACGCCCCCGGGCGGCGGCGGCCATGGCGGGGCCGCTCCGGAGCTGCCGCCC
GCGCAGCCCAGGCCCGACGCCGGCGGCGACTTCTACCTGCGCTGCTTGGGCAAGAACGGG
GTATTCGTGGACGGCGTGTTCCAGAGGCGCGGGGCGCCGCCGCTGCAGCTGCCGCGCGTG
TGCACATTCAGGTTCCCGAGCACAAACATCAAGATAACGTTCACTGCCCTGTCCAGCGAG
AAGAGAGAGAAGCAGGAGGCGTCTGAGTCTCCAGTGAAGGCCGTACAGCCACACATCTCG
CCCCTGACCATCAACATTCCAGACACCATGGCCCACCTCATCAGCCCTCTGCCCTCCCCC
ACGGGAACCATCAGCGCTGCAAACTCCTGCCCCTCCAGCCCCCGGGGAGCGGGGTCTTCA
GGGTACAAGGTGGGCCGAGTGATGCCATCTGACCTCAATTTAATGGCTGACAACTCACAG
CCTGAAAATGAAAAGGAAGCTTCAGGTGGAGACAGCCCGAAGGATGATTCAAAGCCGCCT
TACTCCTACGCGCAGCTGATAGTTCAGGCGATTACGATGGCTCCCGACAAACAGCTCACC
CTGAACGGGATTTATACACACATCACTAAAAATTATCCCTACTACAGGACTGCGGACAAG
GGCTGGCAGAATTCAATTCGCCACAATCTCTCTCTGAATCGTTATTTCATCAAAGTGCCG
CGTTCCCAGGAAGAACCAGGCAAAGGCTCGTTCTGGAGGATAGACCCAGCCTCTGAAAGC
AAATTAATAGAACAGGCTTTTAGGAAACGACGGCCTAGGGGCGTGCCCTGCTTTAGAACC
CCTCTGGGACCGCTCTCTTCTAGGAGTGCCCCAGCCTCTCCCAATCACGCGGGAGTGCTG
TCTGCTCACTCTAGTGGCGCCCAGACCCCTGAGAGCCTGTCGAGGGAAGGTTCGCCGGCC
CCCCTGGAGCCTGAGCCTGGCGCTGCACAGCCCAAACTCGCTGTCATCCAGGAAGCCCGG
TTTGCCCAGAGCGCCCCAGGGTCACCTCTGTCCAGTCAGCCAGTCTTAATCACCGTCCAG
CGGCAGCTACCACAGGCCATCAAGCCTGTCACCTACACTGTGGCCACCCCAGTGACCACC
TCGACCTCCCAGCCACCCGTCGTGCAGACGGTTCACGTCGTCCACCAGATCCCAGCGGTG
TCGGTCACCAGTGTGGCCGGACTGGCCCCAGCGAACACGTACACTGTCTCTGGACAAGCT
GTGGTCACCCCGGCAGCCGTGCTGGCCCCTCCTAAGGCAGAGGCCCAGGAGAATGGAGAC
CACAGGGAAGTCAAAGTGAAAGTAGAGCCTATTCCCGCCATTGGCCACGCCACGCTCGGC
ACTGCCAGCCGGATCATTCAGACGGCACAGACCACCCCGGTCCAGACGGTGACCATAGTA
CAACAGGCACCTCTAGGTCAACACCAGCTACCAATAAAAACTGTAACACAAAACGGCACT
CACGTGGCATCAGTCCCCACTGCGGTCCACGGCCAGGTGAACAATGCCGCGGCGAGTCCT
TTGCACATGTTGGCAACACACGCATCCGCATCGGCCTCCCTGCCCACAAAGCGCCACAAC
GGTGACCAGCCGGAGCAGCCGGAGCTGAAGCGGATCAAGACAGAAGACGGCGAGGGCATC
GTCATTGCCCTGAGCGTGGACACGCCACCGGCAGCCGTAAGGGAAAAGGGTGTCCAGAAC
TAG

Protein Properties

Number of Residues

660

Molecular Weight

69061.5

Theoretical pI

10.06

Pfam Domain Function

FHA (PF00498 )
Fork_head (PF00250 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Forkhead box protein K2
MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNS
SQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNG
VFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHIS
PLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQ
PENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADK
GWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRT
PLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEAR
FAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAV
SVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLG
TASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASP
LHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN

External Links

GenBank ID Protein

31563338

UniProtKB/Swiss-Prot ID

Q01167

UniProtKB/Swiss-Prot Entry Name

FOXK2_HUMAN

PDB IDs