| Identification |
|---|
| HMDB Protein ID
| CDBP03934 |
| Secondary Accession Numbers
| Not Available |
| Name
| Fidgetin-like protein 1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| FIGNL1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in nucleotide binding |
| Specific Function
| May regulate osteoblast proliferation and differentiation (By similarity).
|
| GO Classification
|
| Biological Process |
| osteoblast differentiation |
| osteoblast proliferation |
| regulation of cell cycle |
| negative regulation of apoptotic process |
| ATP metabolic process |
| Cellular Component |
| cytoplasm |
| nucleus |
| Function |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| pyrophosphatase activity |
| binding |
| nucleotide binding |
| catalytic activity |
| hydrolase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| nucleoside-triphosphatase activity |
| hydrolase activity, acting on acid anhydrides |
| Molecular Function |
| magnesium ion binding |
| nucleoside-triphosphatase activity |
| ATP binding |
| hydrolase activity |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| 7p12.1 |
| SNPs
| FIGNL1 |
| Gene Sequence
|
>2025 bp
ATGCAGACCTCCAGCTCTAGATCTGTGCACCTGAGTGAATGGCAGAAGAATTACTTCGCA
ATTACATCTGGCATATGTACCGGACCGAAGGCAGATGCATACCGTGCACAGATATTACGC
ATTCAGTATGCATGGGCAAACTCTGAGATTTCCCAGGTCTGTGCTACCAAACTGTTCAAA
AAATATGCAGAGAAATATTCTGCAATTATTGATTCTGACAATGTTGAATCTGGGTTGAAT
AATTATGCAGAAAACATTTTAACTTTGGCAGGATCTCAACAAACAGATAGTGACAAGTGG
CAGTCTGGATTGTCAATAAATAATGTTTTCAAAATGAGTAGTGTACAGAAGATGATGCAA
GCTGGCAAAAAATTCAAAGACTCTCTGTTGGAACCTGCTCTTGCATCAGTGGTAATCCAT
AAGGAGGCCACTGTCTTTGATCTTCCTAAATTTAGTGTTTGTGGTAGTTCTCAAGAGAGT
GACTCATTACCTAACTCAGCTCATGATCGAGACCGGACCCAAGACTTCCCGGAGAGCAAT
CGTTTGAAACTCCTTCAGAATGCCCAGCCACCTATGGTGACTAACACTGCTAGGACTTGT
CCTACATTCTCAGCACCTGTAGGTGAGTCAGCTACTGCAAAATTCCATGTCACACCATTG
TTTGGAAATGTCAAAAAGGAAAATCACAGCTCTGCAAAAGAAAACATAGGACTTAATGTG
TTCTTATCTAACCAGTCTTGTTTTCCTGCTGCCTGTGAAAATCCACAGAGGAAGTCTTTT
TATGGTTCTGGCACCATTGATGCACTTTCCAATCCAATACTGAATAAGGCTTGTAGTAAA
ACAGAAGATAATGGCCCAAAGGAGGATAGCAGCCTGCCTACATTTAAAACTGCAAAAGAA
CAATTATGGGTAGATCAGCAAAAAAAGTACCACCAACCTCAGCGTGCATCAGGGTCTTCA
TATGGTGGTGTAAAAAAGTCTCTAGGAGCTAGTAGATCCCGAGGGATACTTGGAAAGTTT
GTTCCTCCTATACCCAAGCAAGATGGGGGAGAGCAGAATGGAGGAATGCAATGTAAGCCT
TATGGGGCAGGACCTACAGAACCAGCACATCCAGTTGATGAGCGTCTGAAGAACTTGGAG
CCAAAGATGATTGAACTTATTATGAATGAGATTATGGATCATGGACCTCCAGTAAATTGG
GAAGATATTGCAGGAGTAGAATTTGCTAAAGCCACCATAAAGGAAATAGTTGTGTGGCCC
ATGTTGAGGCCAGACATCTTTACTGGTTTAAGGGGACCCCCTAAAGGAATTTTGCTCTTT
GGTCCTCCTGGGACTGGTAAAACTCTAATTGGCAAGTGCATTGCTAGTCAGTCTGGGGCA
ACATTCTTTAGCATCTCTGCTTCATCCTTAACTTCTAAATGGGTAGGTGAGGGGGAGAAA
ATGGTCCGTGCATTGTTTGCTGTTGCAAGGTGTCAGCAACCAGCTGTGATATTTATTGAC
GAAATTGATTCCTTGTTATCTCAACGGGGAGATGGTGAGCATGAATCTTCTAGAAGGATA
AAAACAGAATTTTTAGTTCAATTAGATGGAGCAACAACATCTTCTGAAGATCGTATCCTA
GTGGTGGGAGCAACAAATCGGCCACAAGAAATTGATGAGGCTGCCCGGAGAAGATTGGTG
AAAAGGCTTTATATTCCCCTCCCAGAAGCTTCAGCCAGGAAACAGATAGTAATTAATCTA
ATGTCCAAAGAGCAGTGTTGCCTCAGTGAAGAAGAAATTGAACAGATTGTACAGCAGTCT
GATGCGTTTTCAGGAGCAGACATGACACAGCTTTGCAGGGAGGCTTCTCTTGGTCCTATT
CGCAGTTTACAAACTGCTGACATTGCTACCATAACACCGGATCAAGTTCGACCCATAGCT
TACATTGATTTTGAAAATGCTTTTAGAACTGTGCGACCTAGTGTTTCTCCAAAAGATTTA
GAGCTTTATGAAAACTGGAACAAAACTTTTGGTTGTGGAAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 674 |
| Molecular Weight
| 74076.355 |
| Theoretical pI
| 7.851 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Fidgetin-like protein 1
MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFK
KYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQ
AGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESN
RLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNV
FLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKE
QLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKP
YGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWP
MLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEK
MVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRIL
VVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQS
DAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL
ELYENWNKTFGCGK
|
| External Links |
|---|
| GenBank ID Protein
| 41393465 |
| UniProtKB/Swiss-Prot ID
| Q6PIW4 |
| UniProtKB/Swiss-Prot Entry Name
| FIGL1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AC018705 |
| GeneCard ID
| FIGNL1 |
| GenAtlas ID
| FIGNL1 |
| HGNC ID
| HGNC:13286 |
| References |
|---|
| General References
| Not Available |