| Identification |
|---|
| HMDB Protein ID
| CDBP03923 |
| Secondary Accession Numbers
| Not Available |
| Name
| Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| DYRK4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| Possible non-essential role in spermiogenesis |
| GO Classification
|
| Function |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12p13.32 |
| SNPs
| DYRK4 |
| Gene Sequence
|
>1563 bp
ATGCCGGCCTCAGAGCTCAAGGCTTCAGAAATACCTTTCCACCCTAGCATTAAAACCCAG
GATCCCAAGGCAGAGGAGAAGTCACCAAAGAAGCAAAAGGTGACTCTGACAGCGGCAGAG
GCCCTAAAGCTTTTTAAGAACCAGCTGTCTCCATATGAACAAAGTGAAATCCTGGGCTAC
GCGGAGCTGTGGTTCCTGGGTCTTGAAGCCAAGAAGCTCGACACGGCTCCTGAGAAATTT
AGCAAGACGAGTTTTGATGATGAGCATGGCTTCTATCTGAAGGTTCTGCATGATCACATT
GCCTACCGCTATGAAGTTCTGGAGACAATCGGGAAGGGGTCCTTTGGACAGGTGGCCAAG
TGCTTGGATCACAAAAACAATGAGCTGGTGGCCCTGAAAATCATCAGGAACAAGAAGAGG
TTTCACCAGCAGGCCCTGATGGAGCTGAAGATCCTGGAAGCTCTCAGAAAGAAGGACAAA
GACAACACCTACAATGTGGTGCATATGAAGGACTTTTTCTACTTTCGCAATCACTTCTGC
ATCACCTTTGAGCTCCTGGGAATCAACTTGTATGAGTTGATGAAGAATAACAACTTTCAA
GGCTTCAGTCTGTCCATAGTTCGGCGCTTCACTCTCTCTGTTTTGAAGTGCTTGCAGATG
CTTTCGGTAGAGAAAATCATTCACTGTGATCTCAAGCCCGAAAATATAGTGCTATACCAA
AAGGGCCAAGCCTCTGTTAAAGTCATTGACTTTGGATCAAGCTGTTATGAACACCAGAAA
GTATACACGTACATCCAAAGCCGGTTCTACCGATCCCCAGAAGTGATCCTGGGCCACCCC
TACGACGTGGCCATTGACATGTGGAGCCTGGGCTGCATCACGGCGGAGTTGTACACGGGC
TACCCCCTGTTCCCCGGGGAGAATGAGGTGGAGCAGCTGGCCTGCATCATGGAGGTGCTG
GGTCTGCCGCCAGCCGGCTTCATTCAGACAGCCTCCAGGAGACAGACATTCTTTGATTCC
AAAGGTTTTCCTAAAAATATAACCAACAACAGGGGGAAAAAAAGATACCCAGATTCCAAG
GACCTCACGATGGTGCTGAAAACCTATGACACCAGCTTCCTGGACTTTCTCAGAAGGTGT
TTGGTATGGGAACCTTCTCTTCGCATGACCCCGGACCAGGCCCTCAAGCATGCTTGGATT
CATCAGTCTCGGAACCTCAAGCCACAGCCCAGGCCCCAGACCCTGAGGAAATCCAATTCC
TTTTTCCCCTCTGAGACAAGGAAGGACAAGGTTCAAGGCTGTCATCACTCGAGCAGAAAA
GCAGATGAGATCACCAAAGAGACTACAGAGAAAACAAAAGATAGCCCCACGAAGCATGTT
CAGCATTCAGGTGATCAGCAGGACTGTCTCCAGCACGGAGCTGACACTGTTCAGCTGCCT
CAACTGGTAGACGCTCCCAAGAAGTCAGAGGCAGCTGTCGGGGCGGAGGTGTCCATGACC
TCCCCAGGACAGAGCAAAAACTTCTCCCTCAAGAACACAAACGTTTTACCCCCTATTGTA
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 520 |
| Molecular Weight
| 59608.0 |
| Theoretical pI
| 9.26 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Dual specificity tyrosine-phosphorylation-regulated kinase 4
MPASELKASEIPFHPSIKTQDPKAEEKSPKKQKVTLTAAEALKLFKNQLSPYEQSEILGY
AELWFLGLEAKKLDTAPEKFSKTSFDDEHGFYLKVLHDHIAYRYEVLETIGKGSFGQVAK
CLDHKNNELVALKIIRNKKRFHQQALMELKILEALRKKDKDNTYNVVHMKDFFYFRNHFC
ITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQ
KGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAELYTG
YPLFPGENEVEQLACIMEVLGLPPAGFIQTASRRQTFFDSKGFPKNITNNRGKKRYPDSK
DLTMVLKTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWIHQSRNLKPQPRPQTLRKSNS
FFPSETRKDKVQGCHHSSRKADEITKETTEKTKDSPTKHVQHSGDQQDCLQHGADTVQLP
QLVDAPKKSEAAVGAEVSMTSPGQSKNFSLKNTNVLPPIV
|
| External Links |
|---|
| GenBank ID Protein
| 28827774 |
| UniProtKB/Swiss-Prot ID
| Q9NR20 |
| UniProtKB/Swiss-Prot Entry Name
| DYRK4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_003845.1 |
| GeneCard ID
| DYRK4 |
| GenAtlas ID
| DYRK4 |
| HGNC ID
| HGNC:3095 |
| References |
|---|
| General References
| Not Available |