Identification |
HMDB Protein ID
| CDBP03917 |
Secondary Accession Numbers
| Not Available |
Name
| Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial |
Description
| Not Available |
Synonyms
|
- Endopeptidase Clp
|
Gene Name
| CLPP |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in serine-type endopeptidase activity |
Specific Function
| Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates |
GO Classification
|
Function |
catalytic activity |
hydrolase activity |
peptidase activity |
peptidase activity, acting on l-amino acid peptides |
endopeptidase activity |
serine-type endopeptidase activity |
Process |
metabolic process |
macromolecule metabolic process |
protein metabolic process |
proteolysis |
|
Cellular Location
|
- Mitochondrion matrix
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 19p13.3 |
SNPs
| CLPP |
Gene Sequence
|
>834 bp
ATGTGGCCCGGAATATTGGTAGGGGGGGCCCGGGTGGCGTCATGCAGGTACCCCGCGCTG
GGGCCTCGCCTCGCCGCTCACTTTCCAGCGCAGCGGCCGCCGCAGCGGACACTCCAGAAC
GGCCTGGCCCTGCAGCGGTGCCTGCACGCGACGGCGACCCGGGCTCTCCCGCTCATTCCC
ATCGTGGTGGAGCAGACGGGTCGCGGCGAGCGCGCCTATGACATCTACTCGCGGCTGCTG
CGGGAGCGCATCGTGTGCGTCATGGGCCCGATCGATGACAGCGTTGCCAGCCTTGTTATC
GCACAGCTCCTCTTCCTGCAATCCGAGAGCAACAAGAAGCCCATCCACATGTACATCAAC
AGCCCTGGTGGTGTGGTGACCGCGGGCCTGGCCATCTACGACACGATGCAGTACATCCTC
AACCCGATCTGCACCTGGTGCGTGGGCCAGGCCGCCAGCATGGGCTCCCTGCTTCTCGCC
GCCGGCACCCCAGGCATGCGCCACTCGCTCCCCAACTCCCGTATCATGATCCACCAGCCC
TCAGGAGGCGCCCGGGGCCAAGCCACAGACATTGCCATCCAGGCAGAGGAGATCATGAAG
CTCAAGAAGCAGCTCTATAACATCTACGCCAAGCACACCAAACAGAGCCTGCAGGTGATC
GAGTCCGCCATGGAGAGGGACCGCTACATGAGCCCCATGGAGGCCCAGGAGTTTGGCATC
TTAGACAAGGTTCTGGTCCACCCTCCCCAGGACGGTGAGGATGAGCCCACGCTGGTGCAG
AAGGAGCCTGTAGAAGCAGCGCCGGCAGCAGAACCTGTCCCAGCTAGCACCTGA
|
Protein Properties |
Number of Residues
| 277 |
Molecular Weight
| 30179.8 |
Theoretical pI
| 8.21 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
MWPGILVGGARVASCRYPALGPRLAAHFPAQRPPQRTLQNGLALQRCLHATATRALPLIP
IVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYIN
SPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQP
SGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGI
LDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAST
|
External Links |
GenBank ID Protein
| 963048 |
UniProtKB/Swiss-Prot ID
| Q16740 |
UniProtKB/Swiss-Prot Entry Name
| CLPP_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| Z50853 |
GeneCard ID
| CLPP |
GenAtlas ID
| CLPP |
HGNC ID
| HGNC:2084 |
References |
General References
| Not Available |