Identification
HMDB Protein ID CDBP03904
Secondary Accession Numbers Not Available
Name Sideroflexin-4
Description Not Available
Synonyms
  1. Breast cancer resistance marker 1
Gene Name SFXN4
Protein Type Transporter
Biological Properties
General Function Involved in cation transmembrane transporter activity
Specific Function Potential iron transporter
GO Classification
Component
membrane
cell part
Function
cation transmembrane transporter activity
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
Process
establishment of localization
transport
transmembrane transport
ion transport
cation transport
Cellular Location
  1. Mitochondrion membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q26.11
SNPs SFXN4
Gene Sequence
>1014 bp
ATGTCCCTGGAACAGGAGGAGGAAACGCAACCTGGGCGGCTCCTAGGACGCAGAGACGCC
GTCCCCGCCTTCATTGAGCCCAACGTGCGCTTCTGGATCACCGAGCGCCAATCCTTTATT
CGACGATTTCTTCAATGGACAGAATTATTAGATCCTACAAATGTGTTCATTTCAGTTGAA
AGTATAGAAAACTCGAGGCAACTATTGTGCACAAATGAAGATGTTTCCAGCCCTGCCTCG
GCGGACCAAAGGATACAAGAAGCTTGGAAGCGGAGTCTTGCAACAGTGCATCCCGACAGC
AGCAACCTGATCCCCAAGCTTTTTCGACCTGCAGCGTTCCTGCCTTTCATGGCGCCCACG
GTATTTTTGTCAATGACGCCACTGAAAGGGATCAAGTCCGTGATTTTACCTCAGGTTTTC
CTCTGTGCCTACATGGCAGCGTTCAACAGCATCAATGGAAACAGAAGTTACACTTGTAAG
CCACTAGAAAGATCATTACTAATGGCGGGAGCCGTTGCTTCTTCAACTTTCTTAGGAGTA
ATCCCTCAGTTTGTCCAGATGAAGTATGGCCTGACTGGCCCTTGGATTAAAAGACTCTTA
CCTGTGATCTTCCTCGTGCAAGCCAGTGGAATGAATGTCTACATGTCCCGAAGTCTTGAA
TCCATTAAGGGGATTGCGGTCATGGACAAGGAAGGCAATGTCCTGGGTCATTCCAGAATT
GCTGGGACAAAGGCTGTTAGAGAAACGCTAGCATCCAGAATAGTGCTGTTTGGGACCTCA
GCTCTGATTCCTGAAGTCTTCACCTACTTTTTTAAAAGGACCCAGTATTTCAGGAAAAAC
CCAGGGTCATTGTGGATTTTGAAACTGTCTTGTACTGTCCTGGCAATGGGACTGATGGTG
CCATTTTCTTTTAGTATATTTCCACAGATTGGACAGATACAGTACTGTAGTCTTGAAGAG
AAAATTCAGTCTCCAACAGAAGAAACAGAAATCTTTTATCACAGAGGGGTGTAG
Protein Properties
Number of Residues 337
Molecular Weight 37998.0
Theoretical pI 9.55
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["111-131", "133-153", "165-185", "251-271", "293-313"]
Protein Sequence
>Sideroflexin-4
MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVE
SIENSRQLLCTNEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPT
VFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGV
IPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRI
AGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMV
PFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV
GenBank ID Protein 47458811
UniProtKB/Swiss-Prot ID Q6P4A7
UniProtKB/Swiss-Prot Entry Name SFXN4_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_213649.1
GeneCard ID SFXN4
GenAtlas ID SFXN4
HGNC ID HGNC:16088
References
General References Not Available