Identification
HMDB Protein ID CDBP03903
Secondary Accession Numbers Not Available
Name Sideroflexin-3
Description Not Available
Synonyms Not Available
Gene Name SFXN3
Protein Type Transporter
Biological Properties
General Function Involved in cation transmembrane transporter activity
Specific Function Potential iron transporter
GO Classification
Component
membrane
cell part
Function
cation transmembrane transporter activity
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
Process
establishment of localization
transport
transmembrane transport
ion transport
cation transport
Cellular Location
  1. Mitochondrion membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q24.31
SNPs SFXN3
Gene Sequence
>978 bp
ATGGAAAGCAAAATGGGTGAATTGCCTTTAGACATCAACATCCAGGAACCTCGCTGGGAC
CAAAGTACTTTCCTGGGCAGAGCCCGGCACTTTTTCACTGTTACTGATCCTCGAAATCTG
CTGCTGTCCGGGGCACAGCTGGAAGCTTCTCGGAACATCGTGCAGAACTACAGGGCCGGC
GTGGTGACCCCAGGGATCACCGAGGACCAGCTGTGGAGGGCCAAGTATGTGTATGACTCC
GCCTTCCATCCGGACACAGGGGAGAAGGTGGTCCTGATTGGCCGCATGTCAGCCCAGGTG
CCCATGAACATGACCATCACTGGCTGCATGCTCACATTCTACAGGAAGACCCCAACCGTG
GTGTTCTGGCAGTGGGTGAATCAGTCCTTCAATGCCATTGTTAACTACTCCAACCGCAGT
GGTGACACTCCCATCACTGTGAGGCAGCTGGGGACAGCCTATGTGAGTGCCACCACTGGA
GCTGTGGCCACGGCCCTGGGACTCAAATCCCTCACCAAGCACTTGCCCCCCTTGGTCGGC
AGATTTGTGCCCTTTGCAGCAGTGGCAGCTGCCAACTGCATCAACATCCCCCTGATGAGG
CAGAGAGAGCTGCAGGTGGGCATCCCAGTGGCTGATGAGGCAGGTCAGAGGCTTGGCTAC
TCGGTGACTGCAGCCAAGCAGGGAATCTTCCAGGTGGTGATTTCAAGAATCTGCATGGCG
ATTCCTGCCATGGCCATCCCACCACTGATCATGGACACTCTGGAGAAGAAAGACTTCCTG
AAGCGCCGCCCCTGGCTGGGGGCACCCCTGCAGGTGGGACTGGTGGGCTTCTGCCTGGTA
TTTGCAACCCCCCTGTGCTGTGCCCTATTCCCCCAGAAGAGCTCCATACACATAAGCAAC
CTGGAACCAGAGCTGAGAGCTCAGATCCATGAGCAAAACCCCAGCGTTGAAGTGGTCTAC
TACAACAAGGGGCTTTGA
Protein Properties
Number of Residues 325
Molecular Weight 35978.6
Theoretical pI 9.37
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["150-168", "178-198", "230-250", "270-290"]
Protein Sequence
>Sideroflexin-3
MESKMGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAG
VVTPGITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTV
VFWQWVNQSFNAIVNYSNRSGDTPITVRQLGTAYVSATTGAVATALGLKSLTKHLPPLVG
RFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMA
IPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISN
LEPELRAQIHEQNPSVEVVYYNKGL
GenBank ID Protein 22760324
UniProtKB/Swiss-Prot ID Q9BWM7
UniProtKB/Swiss-Prot Entry Name SFXN3_HUMAN
PDB IDs Not Available
GenBank Gene ID AK074707
GeneCard ID SFXN3
GenAtlas ID SFXN3
HGNC ID HGNC:16087
References
General References Not Available