Identification
HMDB Protein ID CDBP03902
Secondary Accession Numbers Not Available
Name Sideroflexin-2
Description Not Available
Synonyms Not Available
Gene Name SFXN2
Protein Type Transporter
Biological Properties
General Function Involved in cation transmembrane transporter activity
Specific Function Potential iron transporter
GO Classification
Component
membrane
cell part
Function
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
transporter activity
Process
transmembrane transport
ion transport
cation transport
establishment of localization
transport
Cellular Location
  1. Mitochondrion membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q24.32
SNPs SFXN2
Gene Sequence
>969 bp
ATGGAGGCTGACCTGTCTGGCTTTAACATCGATGCCCCCCGTTGGGACCAGCGCACCTTC
CTGGGGAGAGTGAAGCACTTCCTAAACATCACGGACCCCCGCACTGTCTTTGTATCTGAG
CGGGAGCTGGACTGGGCCAAGGTGATGGTGGAGAAGAGCAGGATGGGGGTTGTGCCCCCA
GGCACCCAAGTGGAGCAGCTGCTGTATGCCAAGAAGCTGTATGACTCGGCCTTCCACCCC
GACACTGGGGAGAAGATGAATGTCATCGGGCGCATGTCTTTCCAGCTTCCTGGCGGCATG
ATCATCACGGGCTTCATGCTCCAGTTCTACAGGACGATGCCGGCGGTGATCTTCTGGCAG
TGGGTGAACCAGTCCTTCAATGCCTTAGTCAACTACACCAACAGGAATGCGGCTTCCCCC
ACATCAGTCAGGCAGATGGCCCTTTCCTACTTCACAGCCACAACCACTGCTGTGGCCACG
GCTGTGGGCATGAACATGTTGACAAAGAAAGCGCCGCCCTTGGTGGGCCGCTGGGTGCCC
TTTGCCGCTGTGGCTGCGGCTAACTGTGTCAATATCCCCATGATGCGACAGCAGGAGCTC
ATAAAGGGAATCTGCGTGAAGGACAGGAATGAAAATGAGATTGGTCATTCCCGGAGAGCT
GCGGCCATAGGCATCACCCAAGTAGTTATTTCTCGGATCACCATGTCAGCTCCTGGGATG
ATCTTGCTGCCAGTCATCATGGAAAGGCTTGAGAAATTGCACTTCATGCAGAAAGTCAAG
GTCCTGCACGCCCCATTGCAGGTCATGCTGAGCGGGTGCTTCCTCATCTTCATGGTGCCA
GTGGCGTGTGGGCTTTTCCCACAGAAATGTGAATTGCCAGTTTCCTATCTGGAACCGAAG
CTCCAAGACACTATCAAGGCCAAGTATGGAGAACTTGAGCCTTATGTCTACTTCAATAAG
GGTCTCTAA
Protein Properties
Number of Residues 322
Molecular Weight 36231.5
Theoretical pI 9.87
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["100-122", "142-164", "174-192", "228-250", "265-287"]
Protein Sequence
>Sideroflexin-2
MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPP
GTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQ
WVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVP
FAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGM
ILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEPK
LQDTIKAKYGELEPYVYFNKGL
GenBank ID Protein 30578418
UniProtKB/Swiss-Prot ID Q96NB2
UniProtKB/Swiss-Prot Entry Name SFXN2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_178858.4
GeneCard ID SFXN2
GenAtlas ID SFXN2
HGNC ID HGNC:16086
References
General References Not Available