Identification |
HMDB Protein ID
| CDBP03901 |
Secondary Accession Numbers
| Not Available |
Name
| Sideroflexin-1 |
Description
| Not Available |
Synonyms
|
- TCC
- Tricarboxylate carrier protein
|
Gene Name
| SFXN1 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in cation transmembrane transporter activity |
Specific Function
| Might be involved in the transport of a component required for iron utilization into or out of the mitochondria |
GO Classification
|
Component |
membrane |
cell part |
Function |
cation transmembrane transporter activity |
transporter activity |
transmembrane transporter activity |
substrate-specific transmembrane transporter activity |
ion transmembrane transporter activity |
Process |
establishment of localization |
transport |
transmembrane transport |
ion transport |
cation transport |
|
Cellular Location
|
- Mitochondrion membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| SFXN1 |
Gene Sequence
|
>969 bp
ATGTCTGGAGAACTACCACCAAACATTAACATCAAGGAACCTCGATGGGATCAAAGCACT
TTCATTGGACGAGCCAATCATTTCTTCACTGTAACTGACCCCAGGAACATTCTGTTAACC
AACGAACAACTCGAGAGTGCGAGAAAAATAGTACATGATTACAGGCAAGGAATTGTTCCT
CCTGGTCTTACAGAAAATGAATTGTGGAGAGCAAAGTACATCTATGATTCAGCTTTTCAT
CCTGACACTGGTGAGAAGATGATTTTGATAGGAAGAATGTCAGCCCAGGTTCCCATGAAC
ATGACCATCACAGGTTGTATGATGACGTTTTACAGGACTACGCCGGCTGTGCTGTTCTGG
CAGTGGATTAACCAGTCCTTCAATGCCGTCGTCAATTACACCAACAGAAGTGGAGACGCA
CCCCTCACTGTCAATGAGTTGGGAACAGCTTACGTTTCTGCAACAACTGGTGCCGTAGCA
ACAGCTCTAGGACTCAATGCATTGACCAAGCATGTCTCACCACTGATAGGACGTTTTGTT
CCCTTTGCTGCCGTAGCTGCTGCTAATTGCATTAATATTCCATTAATGAGGCAAAGGGAA
CTCAAAGTTGGCATTCCCGTCACGGATGAGAATGGGAACCGCTTGGGGGAGTCGGCGAAC
GCTGCGAAACAAGCCATCACGCAAGTTGTCGTGTCCAGGATTCTCATGGCAGCCCCTGGC
ATGGCCATCCCTCCATTCATTATGAACACTTTGGAAAAGAAAGCCTTTTTGAAGAGGTTC
CCATGGATGAGTGCACCCATTCAAGTTGGGTTAGTTGGCTTCTGTTTGGTGTTTGCTACA
CCCCTGTGTTGTGCCCTGTTTCCTCAGAAAAGTTCCATGTCTGTGACAAGCTTGGAGGCC
GAGTTGCAAGCTAAGATCCAAGAGAGCCATCCTGAATTGCGACGCGTGTACTTCAATAAG
GGATTGTAA
|
Protein Properties |
Number of Residues
| 322 |
Molecular Weight
| 35619.1 |
Theoretical pI
| 9.41 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["103-120", "147-167", "175-195", "229-249", "267-287"]
|
Protein Sequence
|
>Sideroflexin-1
MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP
PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW
QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV
PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG
MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA
ELQAKIQESHPELRRVYFNKGL
|
External Links |
GenBank ID Protein
| 23618867 |
UniProtKB/Swiss-Prot ID
| Q9H9B4 |
UniProtKB/Swiss-Prot Entry Name
| SFXN1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_022754.5 |
GeneCard ID
| SFXN1 |
GenAtlas ID
| SFXN1 |
HGNC ID
| HGNC:16085 |
References |
General References
| Not Available |