Identification
HMDB Protein ID CDBP03889
Secondary Accession Numbers Not Available
Name NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
Description Not Available
Synonyms
  1. HIRA-interacting protein 5
Gene Name NFU1
Protein Type Metal Binding
Biological Properties
General Function Involved in iron ion binding
Specific Function Iron-sulfur cluster scaffold protein which can assemble [4Fe-2S] clusters and deliver them to target proteins
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
transition metal ion binding
metal cluster binding
iron-sulfur cluster binding
iron ion binding
Process
metabolic process
biosynthetic process
cellular biosynthetic process
cofactor biosynthetic process
metallo-sulfur cluster assembly
iron-sulfur cluster assembly
Cellular Location
  1. Cytoplasm
  2. Mitochondrion
  3. cytosol
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2p15-p13
SNPs NFU1
Gene Sequence
>765 bp
ATGGCGGCGACGGCCAGGCGGGGCTGGGGAGCTGCGGCTGTTGCCGCCGGGCTGCGCAGG
CGGTTCTGTCATATGTTGAAGAATCCATACACCATTAAGAAACAGCCTCTGCATCAGTTT
GTACAAAGACCACTTTTCCCACTACCTGCAGCCTTTTATCACCCAGTGAGATACATGTTT
ATTCAAACACAAGATACCCCAAATCCAAACAGCTTAAAGTTTATACCAGGAAAACCAGTT
CTTGAGACAAGGACCATGGATTTTCCCACCCCAGCTGCAGCATTTCGCTCCCCTCTGGCT
AGGCAGTTATTTAGGATTGAAGGAGTAAAAAGTGTCTTCTTTGGACCAGATTTCATCACT
GTCACAAAGGAAAATGAAGAATTAGACTGGAATTTACTGAAACCAGATATTTATGCAACA
ATCATGGACTTCTTTGCATCTGGCTTACCCCTGGTTACTGAGGAAACACCTTCAGGAGAA
GCAGGATCTGAAGAAGATGATGAAGTTGTGGCAATGATTAAGGAATTGTTAGATACTAGA
ATACGGCCAACTGTGCAGGAAGATGGAGGGGATGTAATCTACAAAGGCTTTGAAGATGGC
ATTGTACAGCTGAAACTCCAGGGTTCTTGTACCAGCTGCCCTAGTTCAATCATTACTCTG
AAAAATGGAATTCAGAACATGCTGCAGTTTTATATTCCGGAGGTAGAAGGCGTAGAACAG
GTTATGGATGATGAATCAGATGAAAAAGAAGCAAACTCACCTTAA
Protein Properties
Number of Residues 254
Molecular Weight 28462.3
Theoretical pI 4.71
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
MAATARRGWGAAAVAAGLRRRFCHMLKNPYTIKKQPLHQFVQRPLFPLPAAFYHPVRYMF
IQTQDTPNPNSLKFIPGKPVLETRTMDFPTPAAAFRSPLARQLFRIEGVKSVFFGPDFIT
VTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPSGEAGSEEDDEVVAMIKELLDTR
IRPTVQEDGGDVIYKGFEDGIVQLKLQGSCTSCPSSIITLKNGIQNMLQFYIPEVEGVEQ
VMDDESDEKEANSP
GenBank ID Protein 50593021
UniProtKB/Swiss-Prot ID Q9UMS0
UniProtKB/Swiss-Prot Entry Name NFU1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001002755.1
GeneCard ID NFU1
GenAtlas ID NFU1
HGNC ID HGNC:16287
References
General References Not Available