Cannabis Compound Database: Showing Protein Epidermis-type lipoxygenase 3 (CDBP03888)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03888

Secondary Accession Numbers

Not Available

Name

Epidermis-type lipoxygenase 3

Description

Not Available

Synonyms

e-LOX-3

Gene Name

ALOXE3

Protein Type

Enzyme

Biological Properties

General Function

Involved in metal ion binding

Specific Function

Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known

GO Classification

Function
oxidoreductase activity
ion binding
cation binding
metal ion binding
binding
catalytic activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
transition metal ion binding
iron ion binding
lipoxygenase activity
Process
metabolic process
cellular metabolic process
organic acid metabolic process
oxoacid metabolic process
carboxylic acid metabolic process
monocarboxylic acid metabolic process
fatty acid metabolic process
oxidation reduction
unsaturated fatty acid metabolic process
icosanoid metabolic process
leukotriene metabolic process

Cellular Location

Not Available

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

17p13.1

SNPs

ALOXE3

Gene Sequence

>2136 bp
ATGGCAGTGTACCGCCTGTGTGTGACCACTGGTCCCTACCTGAGGGCCGGCACACTGGAC
AACATCTCTGTCACACTGGTGGGCACGTGTGGTGAAAGCCCCAAGCAGCGGCTAGATCGA
ATGGGCAGGGACTTCGCCCCTGGATCGGTACAGAAGTACAAGGTGCGTTGCACAGCGGAG
CTGGGTGAGCTCTTGCTGCTGCGTGTACACAAGGAGCGCTACGCTTTCTTCCGCAAGGAC
TCTTGGTACTGTAGCCGCATCTGTGTCACCGAACCGGATGGTAGTGTATCCCACTTCCCC
TGCTATCAGTGGATTGAAGGCTACTGCACCGTGGAGCTGAGGCCAGGAACAGCAAGAACT
ATTTGTCAGGACTCTCTTCCCCTCCTCCTGGATCACAGGACACGGGAGCTCCGGGCCCGA
CAAGAATGCTACCGCTGGAAGATCTATGCCCCTGGCTTCCCCTGCATGGTAGACGTCAAC
AGCTTTCAGGAGATGGAGTCAGACAAGAAATTTGCCTTGACAAAGACGACAACTTGTGTA
GACCAAGGTGACAGCAGTGGGAATCGGTACCTGCCCGGCTTACCCATGAAAATTGACATC
CCATCCCTGATGTACATGGAGCCCAATGTTCGATACTCAGCCACCAAGACGATCTCGCTG
CTCTTCAATGCCATCCCTGCGTCCTTGGGAATGAAGCTTCGAGGGCTGTTGGATCGCAAG
GGCTCCTGGAAGAAGCTGGATGACATGCAGAACATCTTCTGGTGCCATAAGACCTTCACG
ACAAAGTATGTCACAGAGCACTGGTGTGAAGATCACTTCTTTGGGTACCAGTACCTGAAT
GGTGTCAATCCCGTCATGCTCCACTGCATCTCTAGCTTGCCCAGCAAGCTGCCTGTCACC
AATGACATGGTGGCCCCCTTGCTGGGACAGGACACATGCCTGCAGACAGAGCTAGAGAGG
GGGAACATCTTCCTAGCGGACTACTGGATCCTGGCGGAGGCCCCCACCCACTGCCTAAAC
GGCCGCCAGCAGTACGTGGCCGCCCCACTGTGCCTGCTGTGGCTCAGCCCCCAGGGGGCG
CTGGTGCCCTTGGCCATCCAGCTCAGCCAGACCCCCGGGCCTGACAGCCCCATCTTCCTG
CCCACTGACTCCGAATGGGACTGGCTGCTGGCCAAGACGTGGGTGCGCAACTCTGAGTTC
CTGGTGCACGAAAACAACACGCACTTTCTGTGCACGCATTTGCTGTGCGAGGCCTTCGCC
ATGGCCACGCTGCGCCAGCTGCCGCTCTGCCACCCCATCTACAAGCTCCTACTCCCCCAC
ACTCGATACACGCTGCAGGTGAACACCATCGCGAGGGCCACGCTGCTCAACCCCGAGGGC
CTCGTGGACCAGGTCACGTCCATCGGGAGGCAAGGCCTCATCTACCTCATGAGCACGGGC
CTGGCCCACTTCACCTACACCAATTTCTGCCTTCCGGACAGCCTGCGGGCCCGCGGCGTC
CTGGCTATCCCCAACTACCACTACCGAGACGACGGCCTGAAGATCTGGGCGGCCATTGAG
AGCTTTGTCTCAGAAATCGTGGGCTACTATTATCCCAGTGACGCATCTGTGCAGCAGGAT
TCGGAGCTGCAGGCCTGGACTGGCGAGATTTTTGCTCAGGCGTTCCTGGGCCGGGAAAGC
TCAGGTTTCCCAAGCCGGCTGTGCACCCCAGGAGAGATGGTGAAGTTCCTCACTGCAATC
ATCTTCAATTGCTCTGCCCAGCACGCTGCTGTCAACAGTGGGCAGCATGACTTTGGGGCC
TGGATGCCCAATGCTCCATCATCCATGAGGCAGCCCCCACCCCAGACCAAGGGGACCACC
ACCCTGAAGACTTACCTAGACACCCTCCCTGAAGTGAACATCAGCTGTAACAACCTCCTC
CTCTTCTGGTTGGTTAGCCAAGAACCCAAGGACCAGAGGCCCCTGGGCACCTACCCAGAT
GAGCACTTCACAGAGGAGGCCCCGAGGCGGAGCATCGCCGCCTTCCAGAGCCGCCTGGCC
CAGATCTCAAGGGACATCCAGGAGCGGAACCAGGGTCTGGCACTGCCCTACACCTACCTG
GACCCTCCCCTCATTGAGAACAGCGTCTCCATCTAA

Protein Properties

Number of Residues

711

Molecular Weight

80542.6

Theoretical pI

6.96

Pfam Domain Function

PLAT (PF01477 )
Lipoxygenase (PF00305 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Epidermis-type lipoxygenase 3
MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE
LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTART
ICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTCV
DQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDRK
GSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPVT
NDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQGA
LVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFA
MATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYLMSTG
LAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDASVQQD
SELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQHDFGA
WMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLGTYPD
EHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI

External Links

GenBank ID Protein

10441004

UniProtKB/Swiss-Prot ID

Q9BYJ1

UniProtKB/Swiss-Prot Entry Name

LOXE3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF182218

GeneCard ID