Identification |
HMDB Protein ID
| CDBP03887 |
Secondary Accession Numbers
| Not Available |
Name
| Iron-sulfur cluster assembly enzyme ISCU, mitochondrial |
Description
| Not Available |
Synonyms
|
- NifU-like N-terminal domain-containing protein
- NifU-like protein
|
Gene Name
| ISCU |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in iron ion binding |
Specific Function
| Involved in the assembly or repair of the [Fe-S] clusters present in iron-sulfur proteins. Binds iron |
GO Classification
|
Function |
ion binding |
cation binding |
metal ion binding |
binding |
transition metal ion binding |
metal cluster binding |
iron-sulfur cluster binding |
iron ion binding |
protein binding |
Process |
biosynthetic process |
cellular biosynthetic process |
cofactor biosynthetic process |
metallo-sulfur cluster assembly |
iron-sulfur cluster assembly |
metabolic process |
|
Cellular Location
|
- Nucleus
- Isoform 2:Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 12q24.1 |
SNPs
| ISCU |
Gene Sequence
|
>504 bp
ATGGCGGCGGCTGGGGCTTTCCGTCTGAGGCGGGCGGCATCGGCTCTGCTGCTGCGGAGC
CCCCGCCTGCCCGCCCGGGAGCTGTCGGCCCCGGCCCGACTCTATCACAAGAAGGTTGTT
GATCATTATGAAAATCCTAGAAACGTGGGGTCCCTTGACAAGACATCTAAAAATGTTGGA
ACTGGACTGGTGGGGGCTCCAGCATGTGGTGACGTAATGAAATTACAGATTCAAGTGGAT
GAAAAGGGGAAGATTGTGGATGCTAGGTTTAAAACATTTGGCTGTGGTTCCGCAATTGCC
TCCAGCTCATTAGCCACTGAATGGGTGAAAGGAAAGACGGTGGAGGAAGCCTTGACTATC
AAAAACACAGATATCGCCAAGGAGCTCTGCCTTCCTCCCGTGAAACTGCACTGCTCCATG
CTGGCTGAAGATGCAATCAAGGCCGCCCTGGCTGATTACAAATTGAAACAAGAACCCAAA
AAAGGAGAGGCAGAGAAGAAATGA
|
Protein Properties |
Number of Residues
| 167 |
Molecular Weight
| 17936.7 |
Theoretical pI
| 10.13 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
MAAAGAGRLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG
TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI
KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK
|
External Links |
GenBank ID Protein
| 56699456 |
UniProtKB/Swiss-Prot ID
| Q9H1K1 |
UniProtKB/Swiss-Prot Entry Name
| ISCU_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| NM_213595.2 |
GeneCard ID
| ISCU |
GenAtlas ID
| ISCU |
HGNC ID
| HGNC:29882 |
References |
General References
| Not Available |