Identification |
HMDB Protein ID
| CDBP03886 |
Secondary Accession Numbers
| Not Available |
Name
| Iron-sulfur cluster assembly 2 homolog, mitochondrial |
Description
| Not Available |
Synonyms
|
- HESB-like domain-containing protein 1
|
Gene Name
| ISCA2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in structural molecule activity |
Specific Function
| Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly |
GO Classification
|
Function |
binding |
structural molecule activity |
metal cluster binding |
iron-sulfur cluster binding |
Process |
metabolic process |
biosynthetic process |
cellular biosynthetic process |
cofactor biosynthetic process |
metallo-sulfur cluster assembly |
iron-sulfur cluster assembly |
|
Cellular Location
|
- Mitochondrion
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 14q24.3 |
SNPs
| ISCA2 |
Gene Sequence
|
>465 bp
ATGGCTGCCGCCTGGGGGTCGTCCCTAACGGCCGCGACGCAGAGAGCGGTCACTCCCTGG
CCGAGGGGCAGGCTCCTCACGGCCTCCCTGGGACCCCAGGCGCGTCGGGAGGCGTCGTCC
TCCAGCCCCGAGGCCGGCGAAGGGCAGATCCGCCTCACAGACAGTTGCGTCCAGAGGCTT
TTGGAAATCACCGAAGGGTCAGAATTCCTCAGGCTGCAAGTGGAGGGAGGTGGATGCTCC
GGATTCCAATACAAATTTTCACTGGATACAGTTATCAACCCCGACGACAGGGTATTTGAA
CAGGGTGGGGCAAGAGTGGTGGTTGACTCTGATAGCTTGGCCTTCGTGAAAGGGGCCCAG
GTGGACTTCAGCCAAGAACTGATCCGAAGCTCATTTCAAGTGTTGAACAATCCTCAAGCA
CAGCAAGGCTGCTCCTGTGGGTCATCTTTCTCTATCAAACTTTGA
|
Protein Properties |
Number of Residues
| 154 |
Molecular Weight
| 16476.2 |
Theoretical pI
| 4.88 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Iron-sulfur cluster assembly 2 homolog, mitochondrial
MAAAWGSSLTAATQRAVTPWPRGRLLTASLGPQARREASSSSPEAGEGQIRLTDSCVQRL
LEITEGSEFLRLQVEGGGCSGFQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQ
VDFSQELIRSSFQVLNNPQAQQGCSCGSSFSIKL
|
External Links |
GenBank ID Protein
| 160420328 |
UniProtKB/Swiss-Prot ID
| Q86U28 |
UniProtKB/Swiss-Prot Entry Name
| ISCA2_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_194279.2 |
GeneCard ID
| ISCA2 |
GenAtlas ID
| ISCA2 |
HGNC ID
| HGNC:19857 |
References |
General References
| Not Available |