Identification
HMDB Protein ID CDBP03886
Secondary Accession Numbers Not Available
Name Iron-sulfur cluster assembly 2 homolog, mitochondrial
Description Not Available
Synonyms
  1. HESB-like domain-containing protein 1
Gene Name ISCA2
Protein Type Enzyme
Biological Properties
General Function Involved in structural molecule activity
Specific Function Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly
GO Classification
Function
binding
structural molecule activity
metal cluster binding
iron-sulfur cluster binding
Process
metabolic process
biosynthetic process
cellular biosynthetic process
cofactor biosynthetic process
metallo-sulfur cluster assembly
iron-sulfur cluster assembly
Cellular Location
  1. Mitochondrion
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 14q24.3
SNPs ISCA2
Gene Sequence
>465 bp
ATGGCTGCCGCCTGGGGGTCGTCCCTAACGGCCGCGACGCAGAGAGCGGTCACTCCCTGG
CCGAGGGGCAGGCTCCTCACGGCCTCCCTGGGACCCCAGGCGCGTCGGGAGGCGTCGTCC
TCCAGCCCCGAGGCCGGCGAAGGGCAGATCCGCCTCACAGACAGTTGCGTCCAGAGGCTT
TTGGAAATCACCGAAGGGTCAGAATTCCTCAGGCTGCAAGTGGAGGGAGGTGGATGCTCC
GGATTCCAATACAAATTTTCACTGGATACAGTTATCAACCCCGACGACAGGGTATTTGAA
CAGGGTGGGGCAAGAGTGGTGGTTGACTCTGATAGCTTGGCCTTCGTGAAAGGGGCCCAG
GTGGACTTCAGCCAAGAACTGATCCGAAGCTCATTTCAAGTGTTGAACAATCCTCAAGCA
CAGCAAGGCTGCTCCTGTGGGTCATCTTTCTCTATCAAACTTTGA
Protein Properties
Number of Residues 154
Molecular Weight 16476.2
Theoretical pI 4.88
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Iron-sulfur cluster assembly 2 homolog, mitochondrial
MAAAWGSSLTAATQRAVTPWPRGRLLTASLGPQARREASSSSPEAGEGQIRLTDSCVQRL
LEITEGSEFLRLQVEGGGCSGFQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQ
VDFSQELIRSSFQVLNNPQAQQGCSCGSSFSIKL
GenBank ID Protein 160420328
UniProtKB/Swiss-Prot ID Q86U28
UniProtKB/Swiss-Prot Entry Name ISCA2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_194279.2
GeneCard ID ISCA2
GenAtlas ID ISCA2
HGNC ID HGNC:19857
References
General References Not Available