Identification
HMDB Protein ID CDBP03885
Secondary Accession Numbers Not Available
Name Iron-sulfur cluster assembly 1 homolog, mitochondrial
Description Not Available
Synonyms
  1. HESB-like domain-containing protein 2
  2. Iron-sulfur assembly protein IscA
  3. hIscA
Gene Name ISCA1
Protein Type Enzyme
Biological Properties
General Function Involved in structural molecule activity
Specific Function Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly
GO Classification
Function
metal cluster binding
iron-sulfur cluster binding
binding
structural molecule activity
Process
metabolic process
biosynthetic process
cellular biosynthetic process
cofactor biosynthetic process
metallo-sulfur cluster assembly
iron-sulfur cluster assembly
Cellular Location
  1. Mitochondrion
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9q21.33
SNPs ISCA1
Gene Sequence
>390 bp
ATGTCGGCTTCCTTAGTCCGGGCAACTGTCCGGGCTGTGAGCAAGAGGAAGCTGCAGCCC
ACCCGGGCAGCCCTCACCCTGACACCTTCAGCAGTAAACAAGATAAAACAACTTCTTAAA
GATAAGCCTGAGCATGTAGGTGTAAAAGTTGGTGTCCGAACCAGGGGCTGTAATGGCCTT
TCTTATACTCTAGAATATACAAAGACAAAAGGAGATTCTGATGAAGAAGTTATTCAAGAT
GGAGTCAGAGTATTCATCGAAAAGAAAGCACAGCTAACACTTTTAGGAACAGAAATGGAC
TATGTTGAAGACAAATTATCCAGTGAGTTTGTGTTCAATAACCCAAACATCAAAGGGACT
TGTGGCTGTGGAGAAAGCTTTAATATTTGA
Protein Properties
Number of Residues 129
Molecular Weight 14179.2
Theoretical pI 9.55
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Iron-sulfur cluster assembly 1 homolog, mitochondrial
MSASLVRATVRAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGL
SYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSEFVFNNPNIKGT
CGCGESFNI
GenBank ID Protein 52426768
UniProtKB/Swiss-Prot ID Q9BUE6
UniProtKB/Swiss-Prot Entry Name ISCA1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_030940.3
GeneCard ID ISCA1
GenAtlas ID ISCA1
HGNC ID HGNC:28660
References
General References Not Available