Identification
HMDB Protein ID CDBP03883
Secondary Accession Numbers Not Available
Name Iron-sulfur cluster co-chaperone protein HscB, mitochondrial
Description Not Available
Synonyms
  1. DnaJ homolog subfamily C member 20
  2. Hsc20
Gene Name HSCB
Protein Type Enzyme
Biological Properties
General Function Involved in heat shock protein binding
Specific Function May act as a co-chaperone in iron-sulfur cluster assembly in mitochondria
GO Classification
Function
heat shock protein binding
chaperone binding
binding
protein binding
Process
metabolic process
macromolecule metabolic process
cellular protein metabolic process
protein folding
protein metabolic process
Cellular Location
  1. Mitochondrion (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 22q12.1
SNPs HSCB
Gene Sequence
>708 bp
ATGTGGCGGGGGAGAGCCGGGGCTTTGCTCCGGGTGTGGGGGTTTTGGCCGACAGGGGTT
CCCAGAAGGAGACCGCTAAGCTGCGATGCTGCGTCGCAGGCGGGAAGCAATTATCCCCGC
TGTTGGAACTGCGGCGGCCCATGGGGCCCCGGGCGGGAGGACAGGTTCTTCTGCCCACAG
TGCCGAGCGCTGCAGGCACCTGACCCCACTCGAGACTACTTCAGCCTTATGGACTGCAAC
CGTTCCTTCAGAGTTGATACAGCGAAGCTCCAGCACAGGTACCAGCAACTGCAGCGTCTT
GTCCACCCAGATTTCTTCAGCCAGAGGTCTCAGACTGAAAAGGACTTCTCAGAGAAGCAT
TCGACCCTGGTGAATGATGCCTATAAGACCCTCCTGGCCCCCCTGAGCAGAGGACTGTAC
CTTCTAAAGCTCCATGGAATAGAGATTCCTGAAAGGACAGATTATGAAATGGACAGGCAA
TTCCTCATAGAAATAATGGAAATCAATGAAAAACTCGCAGAAGCTGAAAGTGAAGCTGCC
ATGAAAGAGATTGAATCCATTGTCAAAGCTAAACAGAAAGAATTTACTGACAATGTGAGC
AGTGCTTTTGAACAAGATGACTTTGAAGAAGCCAAGGAAATTTTGACAAAGATGAGATAC
TTTTCAAATATAGAAGAAAAGATCAAGTTAAAGAAGATTCCCCTTTAA
Protein Properties
Number of Residues 235
Molecular Weight 27422.0
Theoretical pI 7.8
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Iron-sulfur cluster co-chaperone protein HscB, mitochondrial
MWRGRAGALLRVWGFWPTGVPRRRPLSCDAASQAGSNYPRCWNCGGPWGPGREDRFFCPQ
CRALQAPDPTRDYFSLMDCNRSFRVDTAKLQHRYQQLQRLVHPDFFSQRSQTEKDFSEKH
STLVNDAYKTLLAPLSRGLYLLKLHGIEIPERTDYEMDRQFLIEIMEINEKLAEAESEAA
MKEIESIVKAKQKEFTDNVSSAFEQDDFEEAKEILTKMRYFSNIEEKIKLKKIPL
GenBank ID Protein 56203009
UniProtKB/Swiss-Prot ID Q8IWL3
UniProtKB/Swiss-Prot Entry Name HSC20_HUMAN
PDB IDs Not Available
GenBank Gene ID AL023494
GeneCard ID HSCB
GenAtlas ID HSCB
HGNC ID HGNC:28913
References
General References Not Available