Identification
HMDB Protein ID CDBP03875
Secondary Accession Numbers Not Available
Name Membrane-associated progesterone receptor component 2
Description Not Available
Synonyms
  1. Progesterone membrane-binding protein
  2. Steroid receptor protein DG6
Gene Name PGRMC2
Protein Type Receptor
Biological Properties
General Function Involved in heme binding
Specific Function Receptor for steroids (Potential)
GO Classification
Function
binding
transition metal ion binding
iron ion binding
heme binding
ion binding
cation binding
metal ion binding
Cellular Location
  1. Membrane
  2. Single-pass membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4q26
SNPs PGRMC2
Gene Sequence
>672 bp
ATGGCGGCTGGTGATGGGGACGTGAAGCTAGGCACCCTGGGGAGTGGCAGCGAGAGCAGC
AACGACGGCGGCAGCGAGAGTCCAGGCGACGCGGGAGCGGCAGCGGAAGGGGGAGGCTGG
GCGGCGGCGGCGTTGGCGCTTCTGACGGGGGGCGGGGAAATGCTGCTGAACGTGGCGCTG
GTGGCTCTGGTGCTGCTGGGGGCCTACCGGCTGTGGGTGCGCTGGGGGCGGCGGGGTCTG
GGGGCCGGGGCCGGGGCGGGCGAGGAGAGCCCCGCCACCTCTCTGCCTCGCATGAAGAAG
CGGGACTTCAGCTTGGAGCAGCTGCGCCAGTACGACGGCTCCCGCAACCCGCGCATCCTG
CTCGCGGTCAATGGGAAAGTCTTCGACGTGACCAAAGGCAGCAAGTTCTACGGCCCGGCG
GGTCCATATGGAATATTTGCTGGTAGGGATGCCTCCAGAGGACTGGCCACATTTTGCCTA
GATAAAGATGCACTTAGAGATGAATATGATGATCTCTCAGATTTGAATGCAGTACAAATG
GAGAGTGTTCGAGAATGGGAAATGCAGTTTAAAGAAAAATATGATTATGTAGGCAGACTC
CTAAAACCAGGAGAAGAACCATCAGAATATACAGATGAAGAAGATACCAAGGATCACAAT
AAACAGGATTGA
Protein Properties
Number of Residues 223
Molecular Weight 23818.2
Theoretical pI 4.48
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["42-66"]
Protein Sequence
>Membrane-associated progesterone receptor component 2
MAAGDGDVKLGTLGSGSESSNDGGSESPGDAGAAAEGGGWAAAALALLTGGGEMLLNVAL
VALVLLGAYRLWVRWGRRGLGAGAGAGEESPATSLPRMKKRDFSLEQLRQYDGSRNPRIL
LAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDEYDDLSDLNAVQM
ESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEEDTKDHNKQD
GenBank ID Protein 2570007
UniProtKB/Swiss-Prot ID O15173
UniProtKB/Swiss-Prot Entry Name PGRC2_HUMAN
PDB IDs Not Available
GenBank Gene ID AJ002030
GeneCard ID PGRMC2
GenAtlas ID PGRMC2
HGNC ID HGNC:16089
References
General References Not Available