Identification
HMDB Protein ID CDBP03874
Secondary Accession Numbers Not Available
Name Membrane-associated progesterone receptor component 1
Description Not Available
Synonyms
  1. mPR
Gene Name PGRMC1
Protein Type Receptor
Biological Properties
General Function Involved in heme binding
Specific Function Receptor for progesterone
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
transition metal ion binding
iron ion binding
heme binding
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Single-pass membrane protein
  3. Microsome membrane
  4. Single- pass membrane protein
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs PGRMC1
Gene Sequence
>588 bp
ATGGCTGCCGAGGATGTGGTGGCGACTGGCGCCGACCCAAGCGATCTGGAGAGCGGCGGG
CTGCTGCATGAGATTTTCACGTCGCCGCTCAACCTGCTGCTGCTTGGCCTCTGCATCTTC
CTGCTCTACAAGATCGTGCGCGGGGACCAGCCGGCGGCCAGCGGCGACAGCGACGACGAC
GAGCCGCCCCCTCTGCCCCGCCTCAAGCGGCGCGACTTCACCCCCGCCGAGCTGCGGCGC
TTCGACGGCGTCCAGGACCCGCGCATACTCATGGCCATCAACGGCAAGGTGTTCGATGTG
ACCAAAGGCCGCAAATTCTACGGGCCCGAGGGGCCGTATGGGGTCTTTGCTGGAAGAGAT
GCATCCAGGGGCCTTGCCACATTTTGCCTGGATAAGGAAGCACTGAAGGATGAGTACGAT
GACCTTTCTGACCTCACTGCTGCCCAGCAGGAGACTCTGAGTGACTGGGAGTCTCAGTTC
ACTTTCAAGTATCATCACGTGGGCAAACTGCTGAAGGAGGGGGAGGAGCCCACTGTGTAC
TCAGATGAGGAAGAACCAAAAGATGAGAGTGCCCGGAAAAATGATTAA
Protein Properties
Number of Residues 195
Molecular Weight 21670.9
Theoretical pI 4.3
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["25-43"]
Protein Sequence
>Membrane-associated progesterone receptor component 1
MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDD
EPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRD
ASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVY
SDEEEPKDESARKND
GenBank ID Protein 5729875
UniProtKB/Swiss-Prot ID O00264
UniProtKB/Swiss-Prot Entry Name PGRC1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_006667.3
GeneCard ID PGRMC1
GenAtlas ID PGRMC1
HGNC ID HGNC:16090
References
General References Not Available