Showing Protein Nuclear factor erythroid 2-related factor 1 (CDBP03871)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03871
Secondary Accession Numbers Not Available
Name Nuclear factor erythroid 2-related factor 1
Description Not Available
Synonyms
  1. Locus control region-factor 1
  2. NF-E2-related factor 1
  3. NFE2-related factor 1
  4. Nuclear factor, erythroid derived 2, like 1
  5. TCF-11
  6. Transcription factor 11
  7. Transcription factor HBZ17
  8. Transcription factor LCR-F1
Gene Name NFE2L1
Protein Type Transcription Factor
Biological Properties
General Function Involved in sequence-specific DNA binding transcription factor activity
Specific Function Activates erythroid-specific, globin gene expression
GO Classification
Function
protein dimerization activity
sequence-specific dna binding
sequence-specific dna binding transcription factor activity
binding
protein binding
nucleic acid binding
dna binding
Process
biological regulation
regulation of biological process
regulation of metabolic process
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
regulation of transcription, dna-dependent
Cellular Location
  1. Nucleus
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 17q21.3
SNPs NFE2L1
Gene Sequence 
>2319 bp
ATGCTTTCTCTGAAGAAATACTTAACGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGT
TTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACTCCGG
GAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAAT
ACCTTGGATGGCTATGGTATCCACCCCAAGAGCATAGACCTGGACAATTACTTCACTGCC
CGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGAGGTA
AATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCA
GGCCTCGCCCTCGAGAGTTCCAGTGGCCTCCAAGATGTGACAGGCCCAGACAACGGGGTG
CGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGTAGCC
CCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGA
CAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAG
CAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGC
GCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCA
CAGGTGCCTAGTGGGGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCTG
GAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGACATTTCCAGCATAACA
GAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTT
CTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATC
ATGGAAATGCAGGCCATGGAAGTGAACACATCAGCAAGTGAAATCCTGTACAGTGCCCCT
CCTGGAGACCCACTGAGCACCAACTACAGCCTTGCCCCCAACACTCCCATCAATCAGAAT
GTCAGCCTGCATCAGGCGTCCCTGGGGGGCTGCAGCCAGGACTTCTTACTCTTCAGCCCC
GAGGTGGAAAGCCTGCCTGTGGCCAGTAGCTCCACGCTGCTCCCGTTGGCCCCCAGCAAT
TCTACCAGCCTCAACTCCACCTTCGGCTCCACCAACCTGACAGGGCTCTTCTTTCCACCC
CAGCTCAATGGCACAGCCAATGACACAGCAGGCCCAGAGCTGCCTGACCCTTTGGGGGGT
CTGTTAGATGAAGCTATGTTGGATGAGATCAGCCTTATGGACCTGGCCATTGAAGAAGGC
TTTAACCCTGTGCAGGCCTCCCAGCTGGAGGAGGAATTTGACTCTGACTCAGGCCTTTCC
TTAGACTCGAGCCATAGCCCTTCTTCCCTAAGCAGCTCTGAAGGCAGTTCTTCCTCTTCT
TCCTCCTCCTCTTCCTCTTCTTCCTCTGCTTCTTCCTCTGCCTCTTCCTCCTTTTCTGAG
GAAGGTGCGGTTGGCTACAGCTCTGACTCTGAGACCCTGGATCTGGAAGAGGCCGAGGGT
GCTGTGGGCTACCAGCCTGAGTATTCCAAGTTCTGCCGCATGAGCTACCAGGATCCAGCT
CAGCTCTCATGCCTGCCCTACCTGGAGCACGTGGGCCACAACCACACATACAACATGGCA
CCCAGTGCCCTGGACTCAGCCGACCTGCCACCACCCAGTGCCCTCAAGAAAGGCAGCAAG
GAGAAGCAGGCTGACTTCCTGGACAAGCAGATGAGCCGGGATGAGCACCGAGCCCGAGCC
ATGAAGATCCCTTTCACCAATGACAAAATCATCAACCTGCCTGTGGAGGAGTTCAATGAA
CTGCTGTCCAAATACCAGTTGAGTGAAGCCCAGCTGAGCCTCATCCGAGACATCCGGCGC
CGGGGCAAGAACAAGATGGCGGCGCAGAACTGCCGCAAGCGCAAGCTGGACACCATCCTG
AATCTGGAGCGTGATGTGGAGGACCTGCAGCGTGACAAAGCCCGGCTGCTGCGGGAGAAA
GTGGAGTTCCTGCGCTCCCTGCGACAGATGAAGCAGAAGGTCCAGAGCCTGTACCAGGAG
GTGTTTGGGCGGCTGCGAGATGAGAACGGACGACCCTACTCGCCCAGTCAGTATGCGCTC
CAGTACGCCGGGGACGGCAGTGTCCTCCTCATCCCCCGCACGATGGCCGACCAGCAGGCC
CGGCGGCAGGAGAGGAAGCCAAAGGACCGGAGAAAGTGA
Protein Properties
Number of Residues 772
Molecular Weight 84702.8
Theoretical pI 4.25
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Nuclear factor erythroid 2-related factor 1
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRN
TLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNS
GLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPA
QVPSGEDQTALSLEECLRLLEATCPFGENAEFPADISSITEAVPSESEPPALQNNLLSPL
LTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYSAPPGDPLSTNYSLAPNTPINQN
VSLHQASLGGCSQDFLLFSPEVESLPVASSSTLLPLAPSNSTSLNSTFGSTNLTGLFFPP
QLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLS
LDSSHSPSSLSSSEGSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEG
AVGYQPEYSKFCRMSYQDPAQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSALKKGSK
EKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRR
RGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQE
VFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK
GenBank ID Protein 4505379
UniProtKB/Swiss-Prot ID Q14494
UniProtKB/Swiss-Prot Entry Name NF2L1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_003204.2
GeneCard ID NFE2L1
GenAtlas ID NFE2L1
HGNC ID HGNC:7781
References
General References Not Available