| Identification |
|---|
| HMDB Protein ID
| CDBP03864 |
| Secondary Accession Numbers
| Not Available |
| Name
| Heme-binding protein 1 |
| Description
| Not Available |
| Synonyms
|
- p22HBP
|
| Gene Name
| HEBP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in circadian rhythm |
| Specific Function
| May act in the binding of free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12p13.1 |
| SNPs
| HEBP1 |
| Gene Sequence
|
>570 bp
ATGTTGGGCATGATCAAGAACTCGCTGTTCGGAAGCGTAGAGACGTGGCCTTGGCAGGTC
CTAAGCAAAGGGGACAAGGAAGAAGTTGCCTATGAAGAAAGGGCCTGTGAAGGGGGCAAA
TTTGCCACAGTAGAAGTGACAGATAAGCCTGTGGATGAGGCTCTACGGGAAGCAATGCCC
AAGGTCGCAAAGTATGCGGGGGGCACCAATGACAAGGGAATTGGGATGGGGATGACAGTC
CCTATTTCCTTTGCTGTGTTCCCCAATGAAGATGGCTCTCTGCAGAAGAAATTAAAAGTC
TGGTTCCGGATTCCAAACCAATTTCAAAGCGACCCACCAGCTCCCAGTGACAAAAGCGTT
AAGATTGAGGAACGGGAAGGCATCACTGTCTATTCCATGCAGTTTGGTGGTTATGCCAAG
GAAGCAGACTACGTAGCACAAGCCACCCGTCTGCGTGCTGCCCTGGAGGGACCAGCCACC
TACCGGGGGGACATCTACTTCTGCACGGGTTATGACCCTCCCATGAAGCCCTACGGACGG
CGCAATGAGATCTGGCTGTTGAAGACATGA
|
| Protein Properties |
|---|
| Number of Residues
| 189 |
| Molecular Weight
| 21096.9 |
| Theoretical pI
| 5.44 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Heme-binding protein 1
MLGMIKNSLFGSVETWPWQVLSKGDKEEVAYEERACEGGKFATVEVTDKPVDEALREAMP
KVAKYAGGTNDKGIGMGMTVPISFAVFPNEDGSLQKKLKVWFRIPNQFQSDPPAPSDKSV
KIEEREGITVYSMQFGGYAKEADYVAQATRLRAALEGTATYRGDIYFCTGYDPPMKPYGR
RNEIWLLKT
|
| External Links |
|---|
| GenBank ID Protein
| 4886908 |
| UniProtKB/Swiss-Prot ID
| Q9NRV9 |
| UniProtKB/Swiss-Prot Entry Name
| HEBP1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF117615 |
| GeneCard ID
| HEBP1 |
| GenAtlas ID
| HEBP1 |
| HGNC ID
| HGNC:17176 |
| References |
|---|
| General References
| Not Available |