| Identification |
|---|
| HMDB Protein ID
| CDBP03857 |
| Secondary Accession Numbers
| Not Available |
| Name
| Fatty acid desaturase 3 |
| Description
| Not Available |
| Synonyms
|
- Cytochrome b5-related protein
|
| Gene Name
| FADS3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in heme binding |
| Specific Function
| Not Available |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transition metal ion binding |
| oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| iron ion binding |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| heme binding |
| oxidoreductase activity |
| Process |
| organic acid metabolic process |
| oxoacid metabolic process |
| carboxylic acid metabolic process |
| monocarboxylic acid metabolic process |
| fatty acid metabolic process |
| fatty acid biosynthetic process |
| oxidation reduction |
| lipid metabolic process |
| metabolic process |
| primary metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11q12-q13.1 |
| SNPs
| FADS3 |
| Gene Sequence
|
>1338 bp
ATGGGCGGCGTCGGGGAGCCGGGACCGCGGGAGGGACCCGCGCAGCCGGGGGCACCGCTG
CCCACCTTCTGCTGGGAGCAGATCCGCGCGCACGACCAGCCCGGCGACAAGTGGCTGGTC
ATCGAGCGCCGCGTCTACGACATCAGCCGCTGGGCACAGCGGCACCCAGGGGGCAGCCGC
CTCATCGGCCACCACGGCGCTGAGGACGCCACGGATGCCTTCCGTGCCTTCCATCAAGAT
CTCAATTTTGTGCGCAAGTTCCTACAGCCCCTGTTGATTGGAGAGCTGGCTCCGGAAGAA
CCCAGCCAGGATGGACCCCTGAATGCGCAGCTGGTCGAGGACTTCCGAGCCCTGCACCAG
GCAGCCGAGGACATGAAGCTGTTTGATGCCAGTCCCACCTTCTTTGCTTTCCTACTGGGC
CACATCCTGGCCATGGAGGTGCTGGCCTGGCTCCTTATCTACCTCCTGGGTCCTGGCTGG
GTGCCCAGTGCCCTGGCCGCCTTCATCCTGGCCATCTCTCAGGCTCAGTCCTGGTGTCTG
CAGCATGACCTGGGCCATGCCTCCATCTTCAAGAAGTCCTGGTGGAACCACGTGGCCCAG
AAGTTCGTGATGGGGCAGCTAAAGGGCTTCTCCGCCCACTGGTGGAACTTCCGCCACTTC
CAGCACCACGCCAAGCCCAACATCTTCCACAAAGACCCAGACGTGACGGTGGCGCCCGTC
TTCCTCCTGGGGGAGTCATCCGTCGAGTATGGCAAGAAGAAACGCAGATACCTACCCTAC
AACCAGCAGCACCTGTACTTCTTCCTGATCGGCCCGCCGCTGCTCACCCTGGTGAACTTT
GAAGTGGAAAATCTGGCGTACATGCTGGTGTGCATGCAGTGGGCGGATTTGCTCTGGGCC
GCCAGCTTCTATGCCCGCTTCTTCTTATCCTACCTCCCCTTCTACGGCGTCCCTGGGGTG
CTGCTCTTCTTTGTTGCTGTCAGGGTCCTGGAAAGCCACTGGTTCGTGTGGATCACACAG
ATGAACCACATCCCCAAGGAGATCGGCCACGAGAAGCACCGGGACTGGGTCAGCTCTCAG
CTGGCAGCCACCTGCAACGTGGAGCCCTCACTTTTCACCAACTGGTTCAGCGGGCACCTC
AACTTCCAGATCGAGCACCACCTCTTCCCCAGGATGCCGAGACACAACTACAGCCGGGTG
GCCCCGCTGGTCAAGTCGCTGTGTGCCAAGCACGGCCTCAGCTACGAAGTGAAGCCCTTC
CTCACCGCGCTGGTGGACATCGTCAGGTCCCTGAAGAAGTCTGGTGACATCTGGCTGGAC
GCCTACCTCCATCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 445 |
| Molecular Weight
| 51144.6 |
| Theoretical pI
| 7.84 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["134-154", "160-180", "264-284", "307-327"]
|
| Protein Sequence
|
>Fatty acid desaturase 3
MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
FLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWA
ASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQ
LAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPF
LTALVDIVRSLKKSGDIWLDAYLHQ
|
| External Links |
|---|
| GenBank ID Protein
| 10798853 |
| UniProtKB/Swiss-Prot ID
| Q9Y5Q0 |
| UniProtKB/Swiss-Prot Entry Name
| FADS3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF084560 |
| GeneCard ID
| FADS3 |
| GenAtlas ID
| FADS3 |
| HGNC ID
| HGNC:3576 |
| References |
|---|
| General References
| Not Available |