| Identification |
|---|
| HMDB Protein ID
| CDBP03844 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cytochrome c oxidase assembly protein COX15 homolog |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| COX15 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein complex assembly |
| Specific Function
| May be involved in the biosynthesis of heme A.
|
| GO Classification
|
| Biological Process |
| heme a biosynthetic process |
| mitochondrial electron transport, cytochrome c to oxygen |
| respiratory chain complex IV assembly |
| respiratory gaseous exchange |
| Cellular Component |
| integral to membrane |
| mitochondrial respiratory chain |
| Component |
| membrane |
| cell part |
| Function |
| catalytic activity |
| Molecular Function |
| cytochrome-c oxidase activity |
| oxidoreductase activity, acting on the CH-CH group of donors |
| Process |
| cellular component organization or biogenesis |
| cellular component organization |
| cellular component assembly |
| macromolecular complex assembly |
| protein complex assembly |
|
| Cellular Location
|
- Mitochondrion membrane
- Multi-pass membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Porphyrin Metabolism |    |  | | heme A biosynthesis | Not Available | Not Available | | Oxidative phosphorylation | Not Available |  | | Porphyrin and chlorophyll metabolism | Not Available | | | Acute Intermittent Porphyria |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| COX15 |
| Gene Sequence
|
>1233 bp
ATGCAGCGATTGCTCTTTCCGCCGTTGAGGGCCTTGAAGGGGAGGCAGTATCTGCCGCTC
CTGGCTCCTAGGGCAGCGCCTAAAGCACAGTGTGATTGCATCAGGCGCCCTTTGAGGCCA
GGGCAATACAGCACCATCTCTGAAGTAGCTTTGCAATCTGGAAGGGGTACAGTGTCCCTT
CCCTCAAAGGCTGCTGAGCGGGTGGTGGGCCGATGGCTCCTGGTCTGCAGTGGAACAGTG
GCTGGAGCAGTTATTCTTGGTGGAGTAACTAGGTTGACAGAGTCTGGCCTCTCGATGGTA
GATTGGCATTTAATAAAGGAGATGAAGCCACCTACAAGCCAAGAGGAATGGGAAGCAGAA
TTCCAAAGATACCAGCAATTTCCAGAATTTAAAATCTTGAATCATGATATGACACTGACA
GAATTCAAGTTCATCTGGTACATGGAGTACTCACACCGAATGTGGGGTCGCCTTGTAGGC
CTTGTGTACATCCTGCCTGCTGCCTACTTTTGGAGAAAGGGCTGGCTCAGCCGTGGCATG
AAAGGACGTGTTCTTGCCCTCTGTGGCCTCGTCTGCTTCCAGGGTCTGTTGGGATGGTAT
ATGGTGAAAAGTGGACTAGAAGAAAAATCAGACTCCCATGACATCCCTCGGGTCAGTCAG
TACCGCCTTGCTGCCCACCTGGGATCAGCCCTGGTTCTTTATTGTGCCAGCTTGTGGACC
TCACTGTCACTGCTACTCCCTCCGCACAAGTTGCCTGAAACCCACCAACTCCTACAGTTG
AGACGATTTGCTCATGGAACAGCAGGTCTGGTGTTCCTTACGGCCCTCTCAGGGGCTTTT
GTGGCAGGGCTAGATGCTGGGCTTGTTTATAACTCCTTTCCCAAAATGGGAGAATCCTGG
ATCCCGGAGGACCTCTTTACCTTCTCCCCCATCCTGAGGAATGTTTTTGAGAATCCCACC
ATGGTGCAGTTTGATCACCGGATTCTGGGAATCACTTCAGTCACTGCCATTACAGTGCTC
TACTTCCTCTCTCGGAGAATTCCCCTTCCTAGAAGGACCAAGATGGCAGCAGTGACTCTG
CTGGCTTTGGCGTATACACAGGTGGGCTTGGGCATCAGCACGCTGCTGATGTATGTCCCA
ACTCCTCTGGCCGCCACTCACCAGTCAGGCTCCTTGGCTTTGCTCACTGGTGCTCTTTGG
CTGATGAATGAACTCCGAAGAGTCCCAAAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 410 |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cytochrome c oxidase assembly protein COX15 homolog
MQRLLFPPLRALKGRQYLPLLAPRAAPRAQCDCIRRPLRPGQYSTISEVALQSGRGTVSL
PSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAE
FQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGM
KGRVLALCGLVCFQGLLGWYMVKSGLEEKSDSHDIPRVSQYRLAAHLGSALVLYCASLWT
SLSLLLPPHKLPETHQLLQLRRFAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESW
IPEDLFTFSPILRNVFENPTMVQFDHRILGITSVTAITVLYFLSRRIPLPRRTKMAAVTL
LALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLTGALWLMNELRRVPK
|
| External Links |
|---|
| GenBank ID Protein
| 3603230 |
| UniProtKB/Swiss-Prot ID
| Q7KZN9 |
| UniProtKB/Swiss-Prot Entry Name
| COX15_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF026850 |
| GeneCard ID
| COX15 |
| GenAtlas ID
| COX15 |
| HGNC ID
| HGNC:2263 |
| References |
|---|
| General References
| Not Available |