Identification
HMDB Protein ID CDBP03838
Secondary Accession Numbers Not Available
Name ATP-binding cassette sub-family B member 10, mitochondrial
Description Not Available
Synonyms
  1. ABC transporter 10 protein
  2. ATP-binding cassette transporter 10
  3. M-ABC2
  4. Mitochondrial ATP-binding cassette 2
Gene Name ABCB10
Protein Type Transporter
Biological Properties
General Function Involved in ATP binding
Specific Function May mediate critical mitochondrial transport functions related to heme biosynthesis
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
hydrolase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
transmembrane transporter activity
atpase activity
transporter activity
active transmembrane transporter activity
nucleoside-triphosphatase activity
primary active transmembrane transporter activity
hydrolase activity, acting on acid anhydrides
p-p-bond-hydrolysis-driven transmembrane transporter activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
atpase activity, coupled to transmembrane movement of substances
pyrophosphatase activity
binding
nucleotide binding
catalytic activity
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Mitochondrion inner membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1q42.13
SNPs ABCB10
Gene Sequence
>2217 bp
ATGCGAGGCCCCCCTGCCTGGCCGCTGCGGCTGCTCGAGCCACCGAGCCCTGCCGAGCCA
GGTCGGCTCCTGCCGGTAGCCTGCGTGTGGGCCGCGGCCAGCCGCGTTCCCGGGTCCCTA
TCGCCGTTCACTGGCCTGAGGCCGGCGCGGCTATGGGGCGCGGGGCCCGCGCTGCTCTGG
GGCGTTGGAGCCGCGCGCCGCTGGAGGAGCGGCTGCCGGGGCGGGGGTCCGGGCGCCTCG
CGGGGCGTCCTGGGCCTCGCGCGGCTCCTGGGGCTGTGGGCTCGCGGCCCCGGCAGCTGC
AGGTGCGGGGCTTTTGCCGGGCCAGGCGCTCCTCGGCTCCCGCGCGCCCGGTTCCCGGGC
GGTCCCGCAGCCGCTGCCTGGGCAGGGGACGAGGCCTGGCGGCGCGGGCCGGCGGCGCCT
CCCGGGGACAAGGGGCGGCTGCGCCCCGCAGCGGCCGGACTCCCGGAGGCCCGGAAGCTC
CTGGGGCTGGCGTACCCTGAGCGCCGGAGGCTGGCAGCTGCGGTTGGATTTCTCACGATG
TCCAGTGTTATCTCCATGTCTGCCCCTTTCTTCCTGGGGAAGATCATTGATGTCATCTAT
ACCAACCCCACTGTGGACTACAGCGACAACCTGACCCGCCTCTGCCTAGGGCTCAGTGCC
GTGTTTCTGTGTGGTGCTGCCGCCAATGCCATTCGTGTCTACCTCATGCAAACTTCAGGT
CAGCGCATTGTGAATAGGCTGAGAACTTCATTATTCTCCTCCATTCTGAGGCAGGAGGTT
GCTTTCTTTGACAAGACTCGCACAGGAGAATTGATTAACCGCCTCTCATCAGACACTGCA
CTCCTGGGGCGCTCAGTGACTGAAAACCTCTCAGATGGGCTCAGGGCCGGGGCCCAGGCT
TCCGTAGGCATCAGTATGATGTTTTTTGTCTCACCTAATCTGGCCACCTTTGTTTTGAGC
GTGGTGCCTCCAGTGTCAATCATTGCTGTAATTTATGGGCGATATCTACGGAAACTGACC
AAAGTCACTCAGGATTCCCTGGCACAAGCCACTCAGCTAGCTGAGGAACGTATTGGAAAT
GTAAGAACTGTTCGAGCTTTTGGGAAAGAAATGACTGAAATCGAGAAATATGCCAGCAAA
GTGGACCATGTAATGCAGTTAGCAAGGAAAGAGGCATTCGCCCGGGCTGGTTTCTTTGGA
GCAACTGGGCTCTCCGGAAACCTGATCGTGCTTTCTGTCCTGTACAAAGGAGGGCTGCTG
ATGGGCAGTGCCCACATGACCGTGGGTGAACTCTCTTCCTTCCTAATGTATGCTTTCTGG
GTTGGAATAAGCATTGGAGGTCTGAGCTCTTTCTACTCGGAGCTGATGAAAGGACTGGGT
GCAGGGGGGCGCCTCTGGGAGCTCCTGGAGAGAGAGCCCAAGCTGCCTTTTAACGAGGGG
GTCATCTTAAATGAGAAAAGCTTCCAGGGTGCTTTGGAGTTTAAGAACGTGCATTTTGCC
TATCCAGCTCGCCCAGAGGTGCCCATATTTCAGGATTTCAGCCTTTCCATTCCGTCAGGA
TCTGTCACGGCACTGGTTGGCCCAAGTGGTTCTGGCAAATCAACAGTGCTTTCACTCCTG
CTGAGGTTGTACGACCCTGCTTCTGGAACTATTAGTCTTGATGGCCATGACATCCGTCAG
CTAAACCCAGTGTGGCTGAGATCCAAAATTGGGACAGTGAGTCAGGAACCCATTTTGTTT
TCTTGCTCTATTGCTGAGAACATTGCTTATGGTGCTGATGACCCTTCCTCTGTGACCGCT
GAGGAAATCCAGAGAGTGGCTGAAGTGGCCAATGCAGTGGCCTTCATCCGGAATTTCCCC
CAAGGGTTCAACACTGTGGTTGGAGAAAAGGGTGTTCTCCTCTCAGGTGGGCAGAAACAG
CGGATTGCGATTGCCCGTGCTCTGCTAAAGAATCCCAAAATTCTTCTCCTAGATGAAGCA
ACCAGTGCGCTGGATGCCGAAAATGAGTACCTTGTTCAAGAAGCTCTAGATCGACTGATG
GATGGAAGAACGGTGTTAGTTATTGCCCATCGTCTGTCCACCATTAAGAATGCTAATATG
GTTGCTGTTCTTGACCAAGGAAAAATTACTGAATATGGAAAACATGAAGAGCTGCTTTCA
AAACCAAATGGGATATACAGAAAACTAATGAACAAACAAAGTTTTATTTCAGCATAA
Protein Properties
Number of Residues 738
Molecular Weight 79146.9
Theoretical pI 10.37
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["171-191", "216-236", "313-333", "408-428", "431-451"]
Protein Sequence
>ATP-binding cassette sub-family B member 10, mitochondrial
MRGPPAWPLRLLEPPSPAEPGRLLPVACVWAAASRVPGSLSPFTGLRPARLWGAGPALLW
GVGAARRWRSGCRGGGPGASRGVLGLARLLGLWARGPGSCRCGAFAGPGAPRLPRARFPG
GPAAAAWAGDEAWRRGPAAPPGDKGRLRPAAAGLPEARKLLGLAYPERRRLAAAVGFLTM
SSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSG
QRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQA
SVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGN
VRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLL
MGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEG
VILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLL
LRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTA
EEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEA
TSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLS
KPNGIYRKLMNKQSFISA
GenBank ID Protein 171184400
UniProtKB/Swiss-Prot ID Q9NRK6
UniProtKB/Swiss-Prot Entry Name ABCBA_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_012089.2
GeneCard ID ABCB10
GenAtlas ID ABCB10
HGNC ID HGNC:41
References
General References Not Available