| Identification |
|---|
| HMDB Protein ID
| CDBP03834 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protein XRP2 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cell morphogenesis |
| Specific Function
| Stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor for ARL3 |
| GO Classification
|
| Function |
| nucleoside diphosphate kinase activity |
| binding |
| catalytic activity |
| phosphotransferase activity, phosphate group as acceptor |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| Process |
| pyrimidine nucleotide metabolic process |
| ctp biosynthetic process |
| pyrimidine nucleotide biosynthetic process |
| pyrimidine nucleoside triphosphate biosynthetic process |
| pyrimidine ribonucleoside triphosphate biosynthetic process |
| utp biosynthetic process |
| purine nucleotide metabolic process |
| purine nucleotide biosynthetic process |
| purine nucleoside triphosphate biosynthetic process |
| purine ribonucleoside triphosphate biosynthetic process |
| gtp biosynthetic process |
| metabolic process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| nucleobase, nucleoside and nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| nucleotide metabolic process |
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasmic side
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| RP2 |
| Gene Sequence
|
>1053 bp
ATGGGCTGCTTCTTCTCCAAGAGACGGAAGGCTGACAAGGAGTCGCGGCCCGAGAACGAG
GAGGAGCGGCCAAAGCAGTACAGCTGGGATCAGCGCGAGAAGGTTGATCCAAAAGACTAC
ATGTTCAGTGGACTGAAGGATGAAACAGTAGGTCGCTTACCTGGGACGGTAGCAGGACAA
CAGTTTCTCATTCAAGACTGTGAGAACTGTAACATCTATATTTTTGATCACTCTGCTACA
GTTACCATTGATGACTGTACTAACTGCATAATTTTTCTGGGACCCGTGAAAGGCAGCGTG
TTTTTCCGGAATTGCAGAGATTGCAAGTGCACATTAGCCTGCCAACAATTTCGTGTGCGA
GATTGTAGAAAGCTGGAAGTCTTTTTGTGTTGTGCCACTCAACCCATCATTGAGTCTTCC
TCAAATATCAAATTTGGATGTTTTCAATGGTACTATCCTGAATTAGCTTTCCAGTTCAAA
GATGCAGGGCTAAGTATCTTCGACAATACATGGAGTAACATTCATGACTTTACACCTGTG
TCAGGAGAACTCAACTGGAGCCTTCTTCCAGAAGATGCTGTGGTTCAGGACTATGTTCCT
ATACCTACTACCGAAGAGCTCAAAGCTGTTCGTGTTTCCACAGAAGCCAATAGAAGCATT
GTTCCAATATCCCGGGGTCAGAGACAGAAGAGCAGCGATGAATCATGCTTAGTGGTATTA
TTTGCTGGTGATTACACTATTGCAAATGCCAGAAAACTAATTGATGAGATGGTTGGTAAA
GGCTTTTTCCTAGTTCAGACAAAGGAAGTGTCCATGAAAGCTGAGGATGCTCAAAGGGTT
TTTCGGGAAAAAGCACCTGACTTCCTTCCTCTTCTGAACAAAGGTCCTGTTATTGCCTTG
GAGTTTAATGGGGATGGTGCTGTAGAAGTATGTCAACTTATTGTAAACGAGATATTCAAT
GGGACCAAGATGTTTGTATCTGAAAGCAAGGAGACGGCATCTGGAGATGTAGACAGCTTC
TACAACTTTGCTGATATACAGATGGGAATATGA
|
| Protein Properties |
|---|
| Number of Residues
| 350 |
| Molecular Weight
| 39640.7 |
| Theoretical pI
| 4.73 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein XRP2
MGCFFSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQ
QFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVR
DCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDFTPV
SGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDESCLVVL
FAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIAL
EFNGDGAVEVCQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI
|
| External Links |
|---|
| GenBank ID Protein
| 3550283 |
| UniProtKB/Swiss-Prot ID
| O75695 |
| UniProtKB/Swiss-Prot Entry Name
| XRP2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ007590 |
| GeneCard ID
| RP2 |
| GenAtlas ID
| RP2 |
| HGNC ID
| HGNC:10274 |
| References |
|---|
| General References
| Not Available |