Cannabis Compound Database: Showing Protein 116 kDa U5 small nuclear ribonucleoprotein component (CDBP03825)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03825

Secondary Accession Numbers

Not Available

Name

116 kDa U5 small nuclear ribonucleoprotein component

Description

Not Available

Synonyms

Elongation factor Tu GTP-binding domain-containing protein 2
SNU114 homolog
U5 snRNP-specific protein, 116 kDa
U5-116 kDa
hSNU114

Gene Name

EFTUD2

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTPase activity

Specific Function

Component of the U5 snRNP complex required for pre-mRNA splicing

GO Classification

Function
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding

Cellular Location

Nucleus

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

17q21.31

SNPs

EFTUD2

Gene Sequence

>2919 bp
ATGGATACCGACTTATATGATGAGTTTGGGAATTATATTGGACCAGAGCTTGATTCTGAT
GAAGATGATGATGAATTGGGTAGAGAGACCAAAGATCTTGATGAGATGGATGATGATGAC
GACGACGATGACGTAGGAGATCATGACGATGACCACCCTGGGATGGAGGTGGTGCTGCAT
GAGGACAAGAAGTACTACCCAACAGCCGAGGAGGTGTATGGTCCTGAGGTGGAGACCATA
GTTCAAGAGGAAGACACTCAGCCTCTCACAGAACCCATTATTAAGCCAGTGAAAACCAAG
AAATTCACTCTGATGGAGCAGACATTACCTGTTACGGTGTATGAGATGGATTTCTTGGCG
GATCTGATGGATAACTCAGAGCTCATCAGAAATGTGACCCTTTGTGGACATCTCCACCAT
GGCAAGACATGTTTTGTGGATTGTTTAATTGAACAGACTCACCCGGAAATCAGAAAGCGC
TATGACCAAGATCTGTGCTATACTGACATCCTCTTCACAGAGCAAGAGAGAGGTGTAGGC
ATCAAAAGCACTCCTGTGACAGTGGTCTTGCCAGACACCAAAGGAAAATCTTATCTCTTC
AATATCATGGACACTCCAGGACATGTGAATTTCTCTGATGAGGTCACAGCTGGCTTGCGC
ATCTCAGATGGAGTGGTCCTTTTCATTGATGCTGCTGAGGGGGTGATGCTGAACACAGAG
CGGCTGATCAAGCATGCGGTGCAGGAGAGGCTGGCAGTCACTGTGTGCATCAACAAGATT
GACCGGCTGATCCTGGAGCTGAAGCTGCCTCCAACTGATGCTTATTACAAGCTGCGCCAC
ATTGTGGATGAGGTCAATGGATTAATAAGCATGTATTCCACTGATGAGAACCTGATCCTT
TCCCCACTCCTGGGTAACGTCTGCTTCTCCAGCTCCCAGTACAGCATCTGCTTCACGCTG
GTCTCCTTTGCCAAGATCTATGCCGACACCTTTGGTGACATTAATTACCAAGAATTTGCT
AAAAGACTCTGGGGTGACATCTACTTCAACCCTAAGACGCGAAAGTTCACCAAAAAGGCC
CCAACTAGCAGCTCCCAGAGAAGTTTCGTGGAGTTTATCTTGGAGCCTCTTTATAAGATC
CTCGCCCAGGTTGTAGGTGACGTGGACACCAGCCTCCCACGGACCCTAGACGAGCTTGGC
ATCCACCTGACGAAGGAGGAGCTGAAGCTGAACATCCGCCCCTTGCTCAGGCTGGTCTGC
AAAAAGTTCTTTGGCGAGTTCACAGGCTTTGTGGACATGTGTGTGCAGCATATCCCTTCT
CCAAAGGTGGGCGCCAAGCCCAAGATTGAGCACACCTACACCGGTGGTGTGGACTCCGAC
CTCGGCGAGGCTATGAGTGACTGTGACCCTGATGGCCCCCTGATGTGCCACACTACTAAG
ATGTACAGCACAGATGATGGAGTCCAGTTTCACGCCTTTGGCCGGGTGCTGAGTGGCACC
ATTCATGCTGGGCAGCCTGTGAAGGTACTGGGGGAGAACTACACCCTGGAGGATGAGGAA
GACTCCCAGATATGCACCGTGGGCCGCCTTTGGATCTCTGTGGCCAGGTACCACATCGAG
GTGAACCGTGTTCCTGCTGGCAACTGGGTTCTGATTGAAGGTGTTGATCAACCAATTGTG
AAGACAGCAACCATAACCGAACCCCGAGGCAATGAGGAGGCTCAGATTTTCCGACCCTTG
AAGTTCAATACCACATCTGTTATCAAGATTGCTGTGGAGCCAGTCAACCCCTCAGAGCTG
CCCAAGATGCTTGATGGCCTGCGCAAGGTCAACAAGAGCTATCCATCCCTCACCACCAAG
GTGGAGGAGTCTGGCGAGCATGTGATCCTGGGCACTGGGGAGCTCTACCTGGACTGTGTG
ATGCATGATTTGCGGAAGATGTACTCAGAGATAGACATCAAGGTGGCTGACCCAGTTGTC
ACGTTTTGTGAGACGGTGGTGGAAACATCCTCCCTCAAGTGCTTTGCTGAAACGCCTAAT
AAGAAGAACAAGATCACCATGATTGCTGAGCCTCTTGAGAAGGGCCTGGCAGAGGACATA
GAGAATGAGGTGGTCCAGATTACGTGGAACAGGAAGAAGCTGGGAGAGTTCTTCCAGACC
AAGTACGATTGGGATCTGCTGGCTGCCCGTTCCATCTGGGCTTTTGGCCCTGATGCGACT
GGCCCCAACATTCTGGTGGATGATACTCTGCCCTCTGAGGTGGACAAGGCTCTTCTTGGT
TCAGTGAAGGACAGCATCGTTCAAGGTTTCCAGTGGGGAACCAGGGAGGGCCCCCTCTGT
GATGAATTGATTCGGAATGTCAAGTTTAAGATCCTGGATGCGGTGGTTGCCCAGGAGCCC
CTGCACCGGGGCGGGGGCCAGATCATCCCCACAGCCAGGAGAGTCGTCTACTCTGCCTTC
CTCATGGCTACTCCTCGTCTGATGGAGCCTTACTACTTTGTAGAGGTCCAGGCCCCTGCA
GATTGCGTCTCTGCAGTTTATACCGTCCTGGCCAGGCGCAGGGGGCACGTGACTCAGGAT
GCACCCATCCCAGGCTCCCCTCTGTACACCATCAAAGCTTTTATCCCGGCCATCGACTCT
TTTGGCTTTGAGACTGATCTCCGGACTCACACCCAGGGACAAGCCTTTTCTCTGTCTGTC
TTCCACCACTGGCAGATTGTGCCTGGTGATCCCCTGGACAAGAGCATTGTCATCCGCCCC
TTGGAGCCACAGCCAGCTCCTCACCTGGCCCGGGAATTCATGATCAAAACCCGCCGTAGG
AAGGGCCTCAGTGAAGATGTGAGCATCAGCAAATTCTTCGATGATCCTATGTTGCTGGAA
CTTGCCAAACAGGATGTTGTGCTCAATTACCCCATGTGA

Protein Properties

Number of Residues

972

Molecular Weight

109434.8

Theoretical pI

4.6

Pfam Domain Function

GTP_EFTU (PF00009 )
GTP_EFTU_D2 (PF03144 )
EFG_C (PF00679 )
EFG_IV (PF03764 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>116 kDa U5 small nuclear ribonucleoprotein component
MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEMDDDDDDDDVGDHDDDHPGMEVVLH
EDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLA
DLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVG
IKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTE
RLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLIL
SPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKA
PTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVC
KKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTK
MYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIE
VNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSEL
PKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVV
TFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQT
KYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLC
DELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPA
DCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSV
FHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLE
LAKQDVVLNYPM

External Links

GenBank ID Protein

12803113

UniProtKB/Swiss-Prot ID

Q15029

UniProtKB/Swiss-Prot Entry Name

U5S1_HUMAN

PDB IDs

Not Available

GenBank Gene ID

BC002360

GeneCard ID