Cannabis Compound Database: Showing Protein Signal recognition particle receptor subunit alpha (CDBP03798)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03798

Secondary Accession Numbers

Not Available

Name

Signal recognition particle receptor subunit alpha

Description

Not Available

Synonyms

DP-alpha
Docking protein alpha
SR-alpha

Gene Name

SRPR

Protein Type

Receptor

Biological Properties

General Function

Involved in nucleotide binding

Specific Function

Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system

GO Classification

Component
receptor complex
macromolecular complex
protein complex
signal recognition particle receptor complex
Function
signal recognition particle binding
nucleoside-triphosphatase activity
ribonucleoprotein binding
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
protein binding
gtpase activity
Process
protein targeting to membrane
cotranslational protein targeting to membrane
establishment of localization
transport
protein transport
srp-dependent cotranslational protein targeting to membrane
intracellular protein transport
protein targeting

Cellular Location

Peripheral membrane protein
Endoplasmic reticulum membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

11q24.2

SNPs

SRPR

Gene Sequence

>1917 bp
ATGCTCGACTTCTTCACCATTTTCTCCAAGGGCGGGCTTGTGCTCTGGTGCTTCCAGGGC
GTTAGCGACTCATGCACCGGACCCGTTAACGCGTTGATTCGTTCCGTGCTGCTGCAGGAA
CGGGGAGGTAACAACTCCTTCACCCATGAGGCACTCACACTCAAGTATAAACTGGACAAC
CAGTTTGAGCTGGTGTTTGTGGTTGGTTTTCAGAAGATCCTGACACTGACATATGTAGAC
AAATTGATAGATGACGTGCATCGGCTGTTTCGGGACAAGTACCGCACAGAGATCCAACAG
CAAAGTGCTTTAAGTTTATTAAATGGCACTTTTGATTTCCAAAATGACTTCCTGCGGCTC
CTTCGTGAAGCAGAGGAGAGCAGTAAGATCCGTGCTCCCACTACCATGAAGAAATTTGAA
GATTCTGAAAAGGCCAAGAAACCTGTGAGGTCCATGATTGAGACACGGGGGGAAAAGCCC
AAGGAAAAAGCAAAGAATAGCAAAAAAAAGGGGGCCAAGAAGGAAGGTTCTGATGGTCCT
TTGGCTACCAGCAAACCAGTCCCTGCAGAAAAGTCAGGTCTTCCAGTGGGTCCTGAGAAC
GGAGTAGAACTTTCCAAAGAGGAGCTGATCCGCAGGAAGCGCGAGGAGTTCATTCAGAAG
CATGGGAGGGGTATGGAGAAGTCCAACAAGTCCACGAAGTCAGATGCTCCAAAGGAGAAG
GGCAAAAAAGCACCCCGGGTGTGGGAACTGGGTGGCTGTGCTAACAAAGAAGTGTTGGAT
TACAGTACTCCCACCACCAATGGAACCCCTGAGGCTGCCTTGTCTGAGGACATCAACCTG
ATTCGAGGGACTGGGTCTGGGGGGCAGCTTCAGGATCTGGACTGCAGCAGCTCTGATGAC
GAAGGGGCTGCTCAAAACTCTACCAAACCTAGTGCGACCAAGGGAACACTGGGTGGCATG
TTTGGTATGCTGAAGGGCCTTGTGGGTTCAAAGAGCTTGAGTCGTGAAGACATGGAATCT
GTGCTGGACAAGATGCGTGATCATCTCATTGCTAAGAACGTGGCTGCAGACATTGCCGTC
CAGCTCTGTGAATCTGTTGCCAACAAGTTGGAAGGGAAGGTGATGGGGACGTTCAGCACG
GTGACTTCCACAGTAAAGCAAGCCCTACAGGAGTCCCTGGTGCAGATTCTGCAGCCACAG
CGTCGTGTAGACATGCTCCGGGACATCATGGATGCCCAGCGTCGCCAGCGCCCTTATGTC
GTCACCTTCTGCGGCGTTAATGGAGTGGGGAAATCTACTAATCTTGCCAAGATTTCCTTC
TGGTTGTTAGAGAATGGCTTCAGTGTCCTCATTGCTGCCTGTGATACATTTCGTGCTGGG
GCCGTGGAGCAGCTGCGTACACACACCCGGCGTTTGAGTGCCCTACACCCTCCAGAGAAG
CATGGTGGCCGCACCATGGTGCAGTTGTTTGAAAAGGGCTATGGCAAGGATGCTGCTGGC
ATTGCCATGGAAGCCATTGCTTTTGCACGTAACCAAGGCTTTGACGTGGTGCTGGTGGAC
ACGGCAGGCCGCATGCAAGACAATGCCCCTCTGATGACTGCCCTGGCCAAACTCATTACT
GTCAATACACCTGATTTGGTGCTGTTTGTAGGAGAAGCCTTAGTAGGCAATGAAGCCGTG
GACCAGCTGGTCAAGTTCAACAGAGCCTTGGCTGACCATTCTATGGCTCAGACACCTCGG
CTCATTGATGGCATTGTTCTTACCAAATTTGATACCATTGATGACAAGGTGGGAGCTGCT
ATTTCTATGACGTACATCACAAGCAAACCCATCGTCTTTGTGGGCACCGGCCAGACCTAC
TGTGACCTACGCAGCCTCAATGCCAAGGCTGTGGTGGCTGCCCTCATGAAGGCTTAA

Protein Properties

Number of Residues

638

Molecular Weight

69810.6

Theoretical pI

9.46

Pfam Domain Function

SRP54 (PF00448 )
SRP54_N (PF02881 )
SRP-alpha_N (PF04086 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Signal recognition particle receptor subunit alpha
MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN
QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL
LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP
LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK
GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD
EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV
QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV
VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK
HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT
VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA
ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA

External Links

GenBank ID Protein

189065456

UniProtKB/Swiss-Prot ID

P08240

UniProtKB/Swiss-Prot Entry Name

SRPR_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AK312377

GeneCard ID