Cannabis Compound Database: Showing Protein Signal recognition particle 54 kDa protein (CDBP03797)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03797

Secondary Accession Numbers

Not Available

Name

Signal recognition particle 54 kDa protein

Description

Not Available

Synonyms

SRP54

Gene Name

SRP54

Protein Type

Enzyme

Biological Properties

General Function

Involved in nucleotide binding

Specific Function

Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)

GO Classification

Component
ribonucleoprotein complex
macromolecular complex
signal recognition particle
Function
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
protein binding
nucleic acid binding
7s rna binding
nucleoside-triphosphatase activity
rna binding
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Process
protein targeting to membrane
cotranslational protein targeting to membrane
establishment of localization
transport
protein transport
srp-dependent cotranslational protein targeting to membrane
intracellular protein transport
protein targeting

Cellular Location

Cytoplasm
Nucleus speckle

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

14q13.2

SNPs

SRP54

Gene Sequence

>1515 bp
ATGGTTCTAGCAGACCTTGGAAGAAAAATAACATCAGCATTACGCTCGTTGAGCAATGCC
ACCATTATCAATGAAGAGGTATTGAATGCTATGCTAAAAGAAGTCTGTACCGCTTTGTTG
GAAGCAGATGTTAATATTAAACTAGTGAAGCAACTAAGAGAAAATGTTAAGTCTGCTATT
GATCTTGAAGAGATGGCATCTGGTCTTAACAAAAGAAAAATGATTCAGCATGCTGTATTT
AAAGAACTTGTGAAGCTTGTAGACCCTGGAGTTAAGGCATGGACACCCACTAAAGGAAAA
CAAAATGTGATTATGTTTGTTGGATTGCAAGGGAGTGGTAAAACAACAACATGTTCAAAG
CTAGCATATTATTACCAGAGGAAAGGTTGGAAGACCTGTTTAATATGTGCAGACACATTC
AGAGCAGGGGCTTTTGACCAACTAAAACAGAATGCTACCAAAGCAAGAATTCCATTTTAT
GGAAGCTATACAGAAATGGATCCTGTCATCATTGCTTCTGAAGGAGTAGAGAAATTTAAA
AATGAAAATTTTGAAATTATTATTGTTGATACAAGTGGCCGCCACAAACAAGAAGACTCT
TTGTTTGAAGAAATGCTTCAAGTTGCTAATGCTATACAACCTGATAACATTGTTTATGTG
ATGGATGCCTCCATTGGGCAGGCTTGTGAAGCCCAGGCTAAGGCTTTTAAAGATAAAGTA
GATGTAGCCTCAGTAATAGTGACAAAACTTGATGGCCATGCAAAAGGAGGTGGTGCACTC
AGTGCAGTCGCTGCCACAAAAAGTCCAATTATTTTCATTGGTACAGGGGAACATATAGAT
GACTTTGAACCTTTCAAAACACAGCCTTTTATTAGCAAACTTCTTGGTATGGGCGACATT
GAAGGACTGATAGATAAAGTCAACGAGTTGAAGTTGGATGACAATGAAGCACTTATAGAG
AAGTTGAAACATGGTCAGTTTACGTTGCGAGACATGTATGAGCAATTTCAAAATATCATG
AAAATGGGCCCCTTCAGTCAGATCTTGGGGATGATCCCTGGTTTTGGGACAGATTTTATG
AGCAAAGGAAATGAACAGGAGTCAATGGCAAGGCTAAAGAAATTAATGACAATAATGGAT
AGTATGAATGATCAAGAACTAGACAGTACGGATGGTGCCAAAGTTTTTAGTAAACAACCA
GGAAGAATCCAAAGAGTAGCAAGAGGATCGGGTGTATCAACAAGAGATGTTCAAGAACTT
TTGACACAATATACCAAGTTTGCACAGATGGTAAAAAAGATGGGAGGTATCAAAGGACTT
TTCAAAGGTGGCGACATGTCTAAGAATGTGAGCCAGTCACAGATGGCAAAATTGAACCAA
CAAATGGCCAAAATGATGGATCCTAGGGTTCTTCATCACATGGGTGGTATGGCAGGACTT
CAGTCAATGATGAGGCAGTTTCAACAGGGTGCTGCTGGCAACATGAAAGGCATGATGGGA
TTCAATAATATGTAA

Protein Properties

Number of Residues

504

Molecular Weight

55704.4

Theoretical pI

9.19

Pfam Domain Function

SRP54 (PF00448 )
SRP54_N (PF02881 )
SRP_SPB (PF02978 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Signal recognition particle 54 kDa protein
MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAI
DLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSK
LAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFK
NENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKV
DVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDI
EGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFM
SKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQEL
LTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGL
QSMMRQFQQGAAGNMKGMMGFNNM

External Links

GenBank ID Protein

189053540

UniProtKB/Swiss-Prot ID

P61011

UniProtKB/Swiss-Prot Entry Name

SRP54_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AK312853

GeneCard ID