Identification |
HMDB Protein ID
| CDBP03794 |
Secondary Accession Numbers
| Not Available |
Name
| Sperm-associated antigen 1 |
Description
| Not Available |
Synonyms
|
- HSD-3.8
- Infertility-related sperm protein Spag-1
|
Gene Name
| SPAG1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in binding |
Specific Function
| Plays a role in fertilization. Binds GTP and has GTPase activity |
GO Classification
|
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:8 |
Locus
| 8q22.2 |
SNPs
| SPAG1 |
Gene Sequence
|
>2781 bp
ATGACCACCAAAGATTATCCATCATTGTGGGGCTTTGGAACAACAAAAACATTCAAAATT
CCCATTGAACATCTAGATTTCAAATACATTGAAAAATGTTCAGATGTTAAACATCTGGAA
AAAATTCTTTGCGTGCTCAGATCTGGTGAGGAAGGATATTATCCTGAACTTACAGAATTT
TGTGAAAAGCATCTTCAAGCCTTGGCCCCTGAAAGCAGAGCTTTGAGGAAAGATAAACCA
GCAGCAACAGCAGCCAGTTTTACAGCTGAAGAATGGGAAAAAATTGATGGTGATATAAAG
AGTTGGGTATCAGAAATTAAAAAAGAAGAAGATAAAATGCACTTTCATGAAACTGAGACA
TTTCCAGCAATGAAAGATAATTTGCCTCCAGTTCGTGGTTCAAACAGCTGTCTTCATGTA
GGCAAGGAAAAATATTCTAAAAGACCAACTAAAAAGAAAACTCCAAGGGATTACGCGGAA
TGGGATAAATTTGACGTGGAGAAGGAATGTTTAAAAATTGATGAAGATTACAAAGAAAAG
ACGGTAATAGACAAGTCACACTTGTCTAAAATTGAGACAAGAATAGATACAGCAGGTCTA
ACTGAGAAAGAAAAGGATTTTCTTGCCACTCGTGAAAAGGAGAAAGGAAATGAAGCTTTC
AACTCAGGAGATTATGAAGAAGCAGTGATGTATTATACCAGGAGCATATCAGCGCTTCCC
ACTGTAGTTGCCTATAACAATCGAGCTCAAGCAGAAATCAAATTACAGAACTGGAATAGT
GCTTTTCAGGATTGTGAAAAGGTCTTGGAGTTAGAACCTGGAAACGTAAAGGCTCTTCTG
CGTCGTGCTACTACATATAAACATCAAAACAAGCTCCGGGAAGCTACAGAAGATTTGAGT
AAAGTACTAGATGTTGAGCCTGATAATGATTTGGCCAAGAAAACCTTGTCAGAGGTTGAA
AGAGATCTGAAAAATTCTGAAGCTGCATCTGAGACTCAAACCAAAGGGAAAAGGATGGTT
ATTCAGGAAATAGAAAACTCCGAAGATGAAGAAGGAAAAAGCGGAAGAAAACATGAAGAT
GGCGGTGGAGATAAGAAGCCCGCGGAGCCGGCGGGAGCCGCGCGCGCCGCCCAGCCGTGC
GTCATGGGCAACATCCAGAAGAAGCTGACTGGCAAAGCCGAAGGCGGCAAGCGGCCGGCA
AGGGGCGCGCCGCAGCGGGGCCAGACCCCGGAGGCCGGCGCGGACAAGCGGAGCCCACGG
CGGGCCTCTGCGGCGGCGGCGGCGGGCGGCGGCGCCACCGGGCATCCGGGCGGCGGGCAG
GGCGCGGAGAACCCTGCCGGCCTGAAGAGCCAGGGCAACGAGCTGTTCCGAAGCGGGCAG
TTCGCCGAGGCGGCCGGCAAGTACTCGGCGGCAATCGCGCTCCTGGAGCCAGCAGGAAGT
GAAATTGCAGATGATCTAAGTATCTTATATTCAAATAGAGCAGCATGTTACCTAAAAGAA
GGAAACTGCAGTGGCTGCATTCAAGATTGTAACAGGGCTCTGGAACTTCATCCATTCTCT
ATGAAACCTCTTCTGAGGCGGGCGATGGCCTATGAAACTCTAGAGCAGTATGGGAAAGCT
TATGTGGATTATAAAACAGTGTTGCAGATAGACTGTGGACTCCAGCTAGCAAATGACAGT
GTTAACAGGCTATCAAGAATTTTAATGGAGCTGGATGGACCAAATTGGCGGGAGAAGCTG
TCACCTATTCCTGCTGTGCCTGCTTCTGTGCCACTGCAAGCTTGGCATCCGGCAAAAGAG
ATGATCTCAAAACAAGCAGGAGACTCCAGCAGCCATCGCCAGCAGGGCATCACAGATGAA
AAAACATTTAAAGCCCTTAAGGAAGAAGGAAATCAATGTGTAAATGACAAAAACTATAAA
GACGCCCTCAGTAAATACAGCGAATGCTTAAAGATTAACAATAAGGAATGTGCCATATAT
ACAAACAGAGCTCTCTGTTACTTGAAGCTGTGCCAGTTTGAAGAAGCAAAGCAGGACTGT
GATCAGGCACTTCAGCTAGCTGATGGGAACGTGAAAGCCTTCTATAGACGAGCTCTGGCT
CATAAAGGACTCAAGAATTATCAGAAAAGCTTAATTGATCTCAATAAAGTTATCCTACTA
GATCCAAGTATTATTGAGGCAAAGATGGAACTGGAAGAGGTAACTAGACTCCTTAATCTT
AAGGATAAGACAGCACCATTCAACAAAGAAAAGGAGAGAAGGAAAATTGAGATTCAAGAG
GTGAATGAAGGCAAGGAGGAGCCTGGAAGACCTGCAGGGGAGGTCTCCATGGGATGCCTT
GCTTCTGAGAAGGGAGGCAAAAGCAGCAGGTCACCAGAAGACCCTGAGAAACTTCCGATA
GCCAAGCCTAATAATGCCTATGAATTTGGTCAGATTATAAATGCTCTCAGTACCAGGAAG
GATAAAGAAGCCTGTGCACATCTTTTAGCCATCACTGCACCAAAAGATTTGCCGATGTTT
TTAAGTAACAAACTTGAAGGGGATACATTCCTTCTCCTCATTCAGTCTCTGAAAAATAAT
CTTATTGAAAAAGATCCCTCATTGGTGTATCAGCATCTTTTATACCTGAGTAAAGCAGAA
AGGTTTAAGATGATGTTGACACTAATTAGCAAGGGCCAAAAGGAGCTAATTGAACAGCTG
TTTGAGGACCTTTCGGACACACCAAACAACCATTTTACTTTAGAAGATATACAGGCCCTA
AAAAGGCAGTATGAGCTTTAA
|
Protein Properties |
Number of Residues
| 926 |
Molecular Weight
| 103637.5 |
Theoretical pI
| 6.85 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Sperm-associated antigen 1
MTTKDYPSLWGFGTTKTFKIPIEHLDFKYIEKCSDVKHLEKILCVLRSGEEGYYPELTEF
CEKHLQALAPESRALRKDKPAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHETET
FPAMKDNLPPVRGSNSCLHVGKEKYSKRPTKKKTPRDYAEWDKFDVEKECLKIDEDYKEK
TVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALP
TVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLS
KVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHED
GGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAPQRGQTPEAGADKRSPR
RASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGS
EIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKA
YVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKE
MISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIY
TNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL
DPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCL
ASEKGGKSSRSPEDPEKLPIAKPNNAYEFGQIINALSTRKDKEACAHLLAITAPKDLPMF
LSNKLEGDTFLLLIQSLKNNLIEKDPSLVYQHLLYLSKAERFKMMLTLISKGQKELIEQL
FEDLSDTPNNHFTLEDIQALKRQYEL
|
External Links |
GenBank ID Protein
| 27262636 |
UniProtKB/Swiss-Prot ID
| Q07617 |
UniProtKB/Swiss-Prot Entry Name
| SPAG1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_003114.3 |
GeneCard ID
| SPAG1 |
GenAtlas ID
| SPAG1 |
HGNC ID
| HGNC:11212 |
References |
General References
| Not Available |