Identification
HMDB Protein ID CDBP03794
Secondary Accession Numbers Not Available
Name Sperm-associated antigen 1
Description Not Available
Synonyms
  1. HSD-3.8
  2. Infertility-related sperm protein Spag-1
Gene Name SPAG1
Protein Type Enzyme
Biological Properties
General Function Involved in binding
Specific Function Plays a role in fertilization. Binds GTP and has GTPase activity
GO Classification
Function
binding
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:8
Locus 8q22.2
SNPs SPAG1
Gene Sequence
>2781 bp
ATGACCACCAAAGATTATCCATCATTGTGGGGCTTTGGAACAACAAAAACATTCAAAATT
CCCATTGAACATCTAGATTTCAAATACATTGAAAAATGTTCAGATGTTAAACATCTGGAA
AAAATTCTTTGCGTGCTCAGATCTGGTGAGGAAGGATATTATCCTGAACTTACAGAATTT
TGTGAAAAGCATCTTCAAGCCTTGGCCCCTGAAAGCAGAGCTTTGAGGAAAGATAAACCA
GCAGCAACAGCAGCCAGTTTTACAGCTGAAGAATGGGAAAAAATTGATGGTGATATAAAG
AGTTGGGTATCAGAAATTAAAAAAGAAGAAGATAAAATGCACTTTCATGAAACTGAGACA
TTTCCAGCAATGAAAGATAATTTGCCTCCAGTTCGTGGTTCAAACAGCTGTCTTCATGTA
GGCAAGGAAAAATATTCTAAAAGACCAACTAAAAAGAAAACTCCAAGGGATTACGCGGAA
TGGGATAAATTTGACGTGGAGAAGGAATGTTTAAAAATTGATGAAGATTACAAAGAAAAG
ACGGTAATAGACAAGTCACACTTGTCTAAAATTGAGACAAGAATAGATACAGCAGGTCTA
ACTGAGAAAGAAAAGGATTTTCTTGCCACTCGTGAAAAGGAGAAAGGAAATGAAGCTTTC
AACTCAGGAGATTATGAAGAAGCAGTGATGTATTATACCAGGAGCATATCAGCGCTTCCC
ACTGTAGTTGCCTATAACAATCGAGCTCAAGCAGAAATCAAATTACAGAACTGGAATAGT
GCTTTTCAGGATTGTGAAAAGGTCTTGGAGTTAGAACCTGGAAACGTAAAGGCTCTTCTG
CGTCGTGCTACTACATATAAACATCAAAACAAGCTCCGGGAAGCTACAGAAGATTTGAGT
AAAGTACTAGATGTTGAGCCTGATAATGATTTGGCCAAGAAAACCTTGTCAGAGGTTGAA
AGAGATCTGAAAAATTCTGAAGCTGCATCTGAGACTCAAACCAAAGGGAAAAGGATGGTT
ATTCAGGAAATAGAAAACTCCGAAGATGAAGAAGGAAAAAGCGGAAGAAAACATGAAGAT
GGCGGTGGAGATAAGAAGCCCGCGGAGCCGGCGGGAGCCGCGCGCGCCGCCCAGCCGTGC
GTCATGGGCAACATCCAGAAGAAGCTGACTGGCAAAGCCGAAGGCGGCAAGCGGCCGGCA
AGGGGCGCGCCGCAGCGGGGCCAGACCCCGGAGGCCGGCGCGGACAAGCGGAGCCCACGG
CGGGCCTCTGCGGCGGCGGCGGCGGGCGGCGGCGCCACCGGGCATCCGGGCGGCGGGCAG
GGCGCGGAGAACCCTGCCGGCCTGAAGAGCCAGGGCAACGAGCTGTTCCGAAGCGGGCAG
TTCGCCGAGGCGGCCGGCAAGTACTCGGCGGCAATCGCGCTCCTGGAGCCAGCAGGAAGT
GAAATTGCAGATGATCTAAGTATCTTATATTCAAATAGAGCAGCATGTTACCTAAAAGAA
GGAAACTGCAGTGGCTGCATTCAAGATTGTAACAGGGCTCTGGAACTTCATCCATTCTCT
ATGAAACCTCTTCTGAGGCGGGCGATGGCCTATGAAACTCTAGAGCAGTATGGGAAAGCT
TATGTGGATTATAAAACAGTGTTGCAGATAGACTGTGGACTCCAGCTAGCAAATGACAGT
GTTAACAGGCTATCAAGAATTTTAATGGAGCTGGATGGACCAAATTGGCGGGAGAAGCTG
TCACCTATTCCTGCTGTGCCTGCTTCTGTGCCACTGCAAGCTTGGCATCCGGCAAAAGAG
ATGATCTCAAAACAAGCAGGAGACTCCAGCAGCCATCGCCAGCAGGGCATCACAGATGAA
AAAACATTTAAAGCCCTTAAGGAAGAAGGAAATCAATGTGTAAATGACAAAAACTATAAA
GACGCCCTCAGTAAATACAGCGAATGCTTAAAGATTAACAATAAGGAATGTGCCATATAT
ACAAACAGAGCTCTCTGTTACTTGAAGCTGTGCCAGTTTGAAGAAGCAAAGCAGGACTGT
GATCAGGCACTTCAGCTAGCTGATGGGAACGTGAAAGCCTTCTATAGACGAGCTCTGGCT
CATAAAGGACTCAAGAATTATCAGAAAAGCTTAATTGATCTCAATAAAGTTATCCTACTA
GATCCAAGTATTATTGAGGCAAAGATGGAACTGGAAGAGGTAACTAGACTCCTTAATCTT
AAGGATAAGACAGCACCATTCAACAAAGAAAAGGAGAGAAGGAAAATTGAGATTCAAGAG
GTGAATGAAGGCAAGGAGGAGCCTGGAAGACCTGCAGGGGAGGTCTCCATGGGATGCCTT
GCTTCTGAGAAGGGAGGCAAAAGCAGCAGGTCACCAGAAGACCCTGAGAAACTTCCGATA
GCCAAGCCTAATAATGCCTATGAATTTGGTCAGATTATAAATGCTCTCAGTACCAGGAAG
GATAAAGAAGCCTGTGCACATCTTTTAGCCATCACTGCACCAAAAGATTTGCCGATGTTT
TTAAGTAACAAACTTGAAGGGGATACATTCCTTCTCCTCATTCAGTCTCTGAAAAATAAT
CTTATTGAAAAAGATCCCTCATTGGTGTATCAGCATCTTTTATACCTGAGTAAAGCAGAA
AGGTTTAAGATGATGTTGACACTAATTAGCAAGGGCCAAAAGGAGCTAATTGAACAGCTG
TTTGAGGACCTTTCGGACACACCAAACAACCATTTTACTTTAGAAGATATACAGGCCCTA
AAAAGGCAGTATGAGCTTTAA
Protein Properties
Number of Residues 926
Molecular Weight 103637.5
Theoretical pI 6.85
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Sperm-associated antigen 1
MTTKDYPSLWGFGTTKTFKIPIEHLDFKYIEKCSDVKHLEKILCVLRSGEEGYYPELTEF
CEKHLQALAPESRALRKDKPAATAASFTAEEWEKIDGDIKSWVSEIKKEEDKMHFHETET
FPAMKDNLPPVRGSNSCLHVGKEKYSKRPTKKKTPRDYAEWDKFDVEKECLKIDEDYKEK
TVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALP
TVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLS
KVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHED
GGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAPQRGQTPEAGADKRSPR
RASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGS
EIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKA
YVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKE
MISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIY
TNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL
DPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCL
ASEKGGKSSRSPEDPEKLPIAKPNNAYEFGQIINALSTRKDKEACAHLLAITAPKDLPMF
LSNKLEGDTFLLLIQSLKNNLIEKDPSLVYQHLLYLSKAERFKMMLTLISKGQKELIEQL
FEDLSDTPNNHFTLEDIQALKRQYEL
GenBank ID Protein 27262636
UniProtKB/Swiss-Prot ID Q07617
UniProtKB/Swiss-Prot Entry Name SPAG1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_003114.3
GeneCard ID SPAG1
GenAtlas ID SPAG1
HGNC ID HGNC:11212
References
General References Not Available