Identification
HMDB Protein ID CDBP03781
Secondary Accession Numbers Not Available
Name Ras-related protein R-Ras2
Description Not Available
Synonyms
  1. Ras-like protein TC21
  2. Teratocarcinoma oncogene
Gene Name RRAS2
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion
GO Classification
Component
intracellular
membrane
cell part
Function
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
Process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
biological regulation
regulation of biological process
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasmic side
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11p15.2
SNPs RRAS2
Gene Sequence
>615 bp
ATGGCCGCGGCCGGCTGGCGGGACGGCTCCGGCCAGGAGAAGTACCGGCTCGTGGTGGTC
GGCGGGGGCGGCGTGGGCAAGTCGGCGCTCACCATCCAGTTCATCCAGTCCTATTTTGTA
ACGGATTATGATCCAACCATTGAAGATTCTTACACAAAGCAGTGTGTGATAGATGACAGA
GCAGCCCGGCTAGATATTTTGGATACAGCAGGACAAGAAGAGTTTGGAGCCATGAGAGAA
CAGTATATGAGGACTGGCGAAGGCTTCCTGTTGGTCTTTTCAGTCACAGATAGAGGCAGT
TTTGAAGAAATCTATAAGTTTCAAAGACAGATTCTCAGAGTAAAGGATCGTGATGAGTTC
CCAATGATTTTAATTGGTAATAAAGCAGATCTGGATCATCAAAGACAGGTAACACAGGAA
GAAGGACAACAGTTAGCACGGCAGCTTAAGGTAACATACATGGAGGCATCAGCAAAGATT
AGGATGAATGTAGATCAAGCTTTCCATGAACTTGTCCGGGTTATCAGGAAATTTCAAGAG
CAGGAATGTCCTCCTTCACCAGAACCAACACGGAAAGAAAAAGACAAGAAAGGCTGCCAT
TGTGTCATTTTCTAG
Protein Properties
Number of Residues 204
Molecular Weight 23399.4
Theoretical pI 5.81
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Ras-related protein R-Ras2
MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
QECPPSPEPTRKEKDKKGCHCVIF
GenBank ID Protein 21361416
UniProtKB/Swiss-Prot ID P62070
UniProtKB/Swiss-Prot Entry Name RRAS2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_012250.5
GeneCard ID RRAS2
GenAtlas ID RRAS2
HGNC ID HGNC:17271
References
General References Not Available