Identification |
HMDB Protein ID
| CDBP03781 |
Secondary Accession Numbers
| Not Available |
Name
| Ras-related protein R-Ras2 |
Description
| Not Available |
Synonyms
|
- Ras-like protein TC21
- Teratocarcinoma oncogene
|
Gene Name
| RRAS2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTP binding |
Specific Function
| It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion |
GO Classification
|
Component |
intracellular |
membrane |
cell part |
Function |
purine nucleotide binding |
binding |
nucleotide binding |
catalytic activity |
hydrolase activity |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
gtpase activity |
nucleoside-triphosphatase activity |
hydrolase activity, acting on acid anhydrides |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
pyrophosphatase activity |
Process |
regulation of cellular process |
signal transduction |
intracellular signal transduction |
small gtpase mediated signal transduction |
biological regulation |
regulation of biological process |
|
Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasmic side
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 11p15.2 |
SNPs
| RRAS2 |
Gene Sequence
|
>615 bp
ATGGCCGCGGCCGGCTGGCGGGACGGCTCCGGCCAGGAGAAGTACCGGCTCGTGGTGGTC
GGCGGGGGCGGCGTGGGCAAGTCGGCGCTCACCATCCAGTTCATCCAGTCCTATTTTGTA
ACGGATTATGATCCAACCATTGAAGATTCTTACACAAAGCAGTGTGTGATAGATGACAGA
GCAGCCCGGCTAGATATTTTGGATACAGCAGGACAAGAAGAGTTTGGAGCCATGAGAGAA
CAGTATATGAGGACTGGCGAAGGCTTCCTGTTGGTCTTTTCAGTCACAGATAGAGGCAGT
TTTGAAGAAATCTATAAGTTTCAAAGACAGATTCTCAGAGTAAAGGATCGTGATGAGTTC
CCAATGATTTTAATTGGTAATAAAGCAGATCTGGATCATCAAAGACAGGTAACACAGGAA
GAAGGACAACAGTTAGCACGGCAGCTTAAGGTAACATACATGGAGGCATCAGCAAAGATT
AGGATGAATGTAGATCAAGCTTTCCATGAACTTGTCCGGGTTATCAGGAAATTTCAAGAG
CAGGAATGTCCTCCTTCACCAGAACCAACACGGAAAGAAAAAGACAAGAAAGGCTGCCAT
TGTGTCATTTTCTAG
|
Protein Properties |
Number of Residues
| 204 |
Molecular Weight
| 23399.4 |
Theoretical pI
| 5.81 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Ras-related protein R-Ras2
MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
QECPPSPEPTRKEKDKKGCHCVIF
|
External Links |
GenBank ID Protein
| 21361416 |
UniProtKB/Swiss-Prot ID
| P62070 |
UniProtKB/Swiss-Prot Entry Name
| RRAS2_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_012250.5 |
GeneCard ID
| RRAS2 |
GenAtlas ID
| RRAS2 |
HGNC ID
| HGNC:17271 |
References |
General References
| Not Available |