| Identification |
|---|
| HMDB Protein ID
| CDBP03776 |
| Secondary Accession Numbers
| Not Available |
| Name
| Rab effector Noc2 |
| Description
| Not Available |
| Synonyms
|
- No C2 domains protein
- Rabphilin-3A-like protein
|
| Gene Name
| RPH3AL |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in Rab GTPase binding |
| Specific Function
| Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells |
| GO Classification
|
| Function |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
| enzyme regulator activity |
| rab gtpase binding |
| nucleoside-triphosphatase regulator activity |
| gtpase regulator activity |
| small gtpase regulator activity |
| ion binding |
| Process |
| establishment of localization |
| transport |
| protein transport |
| intracellular protein transport |
|
| Cellular Location
|
- Cytoplasm
- Cytoplasmic vesicle
- secretory vesicle membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17p13.3 |
| SNPs
| RPH3AL |
| Gene Sequence
|
>948 bp
ATGGCCGACACCATCTTCGGCAGCGGGAATGATCAGTGGGTTTGCCCCAATGACCGGCAG
CTTGCCCTTCGAGCCAAGCTGCAGACGGGCTGGTCCGTGCACACCTACCAGACGGAGAAG
CAGAGGAGGAAGCAGCACCTCAGCCCGGCGGAGGTGGAGGCCATCCTGCAGGTCATCCAG
AGGGCAGAGCGGCTCGACGTCCTGGAGCAGCAGAGAATCGGGCGGCTGGTGGAGCGGCTG
GAGACCATGAGGCGGAATGTGATGGGGAACGGCCTGTCCCAGTGTCTGCTCTGCGGGGAG
GTGCTGGGCTTCCTGGGCAGCTCGTCGGTGTTCTGCAAAGACTGCAGGAAGAAAGTCTGC
ACCAAATGTGGGATCGAGGCCTCCCCTGGCCAGAAGCGGCCCCTGTGGCTGTGTAAGATC
TGCAGTGAGCAAAGAGAGGTCTGGAAGAGGTCGGGGGCCTGGTTCTACAAAGGGCTCCCC
AAGTATATCTTGCCCCTGAAGACCCCTGGCCGAGCTGATGACCCCCACTTCCGACCTTTG
CCCACGGAACCGGCAGAGCGAGAGCCCAGAAGCTCTGAGACCAGCCGCATCTACACGTGG
GCCCGAGGAAGAGTGGTTTCCAGTGACAGTGACAGTGACTCGGATCTTAGCTCCTCCAGC
CTAGAGGACAGACTCCCATCCACTGGGGTCAGGGACCGGAAAGGCGACAAACCCTGGAAG
GAGTCAGGTGGCAGCGTGGAGGCCCCCAGGATGGGGTTCACCCACCCGCCGGGCCACCTC
TCTGGGTGCCAGAGCAGCCTGGCCAGTGGTGAGACGGGGACAGGCTCTGCTGACCCGCCA
GGGGGACCCCGCCCCGGGCTGACCCGAAGGGCCCCGGTAAAAGACACACCTGGACGAGCC
CCCGCTGCTGACGCAGCTCCAGCAGGCCCCTCCAGCTGCCTGGGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 315 |
| Molecular Weight
| 34463.7 |
| Theoretical pI
| 9.23 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Rab effector Noc2
MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQ
RAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVC
TKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPL
PTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWK
ESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRA
PAADAAPAGPSSCLG
|
| External Links |
|---|
| GenBank ID Protein
| 5596433 |
| UniProtKB/Swiss-Prot ID
| Q9UNE2 |
| UniProtKB/Swiss-Prot Entry Name
| RPH3L_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF129812 |
| GeneCard ID
| RPH3AL |
| GenAtlas ID
| RPH3AL |
| HGNC ID
| HGNC:10296 |
| References |
|---|
| General References
| Not Available |