Identification |
HMDB Protein ID
| CDBP03773 |
Secondary Accession Numbers
| Not Available |
Name
| Rho-related GTP-binding protein RhoE |
Description
| Not Available |
Synonyms
|
- Protein MemB
- Rho family GTPase 3
- Rho-related GTP-binding protein Rho8
- Rnd3
|
Gene Name
| RND3 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTP binding |
Specific Function
| Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins |
GO Classification
|
Component |
cell part |
intracellular |
Function |
purine nucleotide binding |
binding |
nucleotide binding |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
Process |
signal transduction |
intracellular signal transduction |
small gtpase mediated signal transduction |
biological regulation |
regulation of biological process |
regulation of cellular process |
|
Cellular Location
|
- Golgi apparatus membrane
- Peripheral membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 2q23.3 |
SNPs
| RND3 |
Gene Sequence
|
>735 bp
ATGAAGGAGAGAAGAGCCAGCCAGAAATTATCCAGCAAATCTATCATGGATCCTAATCAG
AACGTGAAATGCAAGATAGTTGTGGTGGGAGACAGTCAGTGTGGAAAAACTGCGCTGCTC
CATGTCTTCGCCAAGGACTGCTTCCCCGAGAATTACGTTCCTACAGTGTTTGAGAATTAC
ACGGCCAGTTTTGAAATCGACACACAAAGAATAGAGTTGAGCCTGTGGGACACTTCGGGT
TCTCCTTACTATGACAATGTCCGCCCCCTCTCTTACCCTGATTCGGATGCTGTGCTGATT
TGCTTTGACATCAGTAGACCAGAGACCCTGGACAGTGTCCTCAAAAAGTGGAAAGGTGAA
ATCCAGGAATTTTGTCCAAATACCAAAATGCTCTTGGTCGGCTGCAAGTCTGATCTGCGG
ACAGATGTTAGTACATTAGTAGAGCTCTCCAATCACAGGCAGACGCCAGTGTCCTATGAC
CAGGGGGCAAATATGGCCAAACAGATTGGAGCAGCTACTTATATCGAATGCTCAGCTTTA
CAGTCGGAAAATAGCGTCAGAGACATTTTTCACGTTGCCACCTTGGCATGTGTAAATAAG
ACAAATAAAAACGTTAAGCGGAACAAATCACAGAGAGCCACAAAGCGGATTTCACACATG
CCTAGCAGACCAGAACTCTCGGCAGTTGCTACGGACTTACGAAAGGACAAAGCGAAGAGC
TGCACTGTGATGTGA
|
Protein Properties |
Number of Residues
| 244 |
Molecular Weight
| 27368.0 |
Theoretical pI
| 8.63 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Rho-related GTP-binding protein RhoE
MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
CTVM
|
External Links |
GenBank ID Protein
| 1171566 |
UniProtKB/Swiss-Prot ID
| P61587 |
UniProtKB/Swiss-Prot Entry Name
| RND3_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| X95282 |
GeneCard ID
| RND3 |
GenAtlas ID
| RND3 |
HGNC ID
| HGNC:671 |
References |
General References
| Not Available |