Identification
HMDB Protein ID CDBP03773
Secondary Accession Numbers Not Available
Name Rho-related GTP-binding protein RhoE
Description Not Available
Synonyms
  1. Protein MemB
  2. Rho family GTPase 3
  3. Rho-related GTP-binding protein Rho8
  4. Rnd3
Gene Name RND3
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins
GO Classification
Component
cell part
intracellular
Function
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
biological regulation
regulation of biological process
regulation of cellular process
Cellular Location
  1. Golgi apparatus membrane
  2. Peripheral membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2q23.3
SNPs RND3
Gene Sequence
>735 bp
ATGAAGGAGAGAAGAGCCAGCCAGAAATTATCCAGCAAATCTATCATGGATCCTAATCAG
AACGTGAAATGCAAGATAGTTGTGGTGGGAGACAGTCAGTGTGGAAAAACTGCGCTGCTC
CATGTCTTCGCCAAGGACTGCTTCCCCGAGAATTACGTTCCTACAGTGTTTGAGAATTAC
ACGGCCAGTTTTGAAATCGACACACAAAGAATAGAGTTGAGCCTGTGGGACACTTCGGGT
TCTCCTTACTATGACAATGTCCGCCCCCTCTCTTACCCTGATTCGGATGCTGTGCTGATT
TGCTTTGACATCAGTAGACCAGAGACCCTGGACAGTGTCCTCAAAAAGTGGAAAGGTGAA
ATCCAGGAATTTTGTCCAAATACCAAAATGCTCTTGGTCGGCTGCAAGTCTGATCTGCGG
ACAGATGTTAGTACATTAGTAGAGCTCTCCAATCACAGGCAGACGCCAGTGTCCTATGAC
CAGGGGGCAAATATGGCCAAACAGATTGGAGCAGCTACTTATATCGAATGCTCAGCTTTA
CAGTCGGAAAATAGCGTCAGAGACATTTTTCACGTTGCCACCTTGGCATGTGTAAATAAG
ACAAATAAAAACGTTAAGCGGAACAAATCACAGAGAGCCACAAAGCGGATTTCACACATG
CCTAGCAGACCAGAACTCTCGGCAGTTGCTACGGACTTACGAAAGGACAAAGCGAAGAGC
TGCACTGTGATGTGA
Protein Properties
Number of Residues 244
Molecular Weight 27368.0
Theoretical pI 8.63
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Rho-related GTP-binding protein RhoE
MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
CTVM
GenBank ID Protein 1171566
UniProtKB/Swiss-Prot ID P61587
UniProtKB/Swiss-Prot Entry Name RND3_HUMAN
PDB IDs
GenBank Gene ID X95282
GeneCard ID RND3
GenAtlas ID RND3
HGNC ID HGNC:671
References
General References Not Available