Cannabis Compound Database: Showing Protein GTP-binding protein Rit1 (CDBP03771)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP03771

Secondary Accession Numbers

Not Available

Name

GTP-binding protein Rit1

Description

Not Available

Synonyms

Ras-like protein expressed in many tissues
Ras-like without CAAX protein 1

Gene Name

RIT1

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTP binding

Specific Function

Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation

GO Classification

Component
membrane
cell part
intracellular
Function
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction

Cellular Location

Cell membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1q22

SNPs

RIT1

Gene Sequence

>660 bp
ATGGATTCTGGAACTCGCCCAGTTGGTAGCTGCTGTAGCAGCCCCGCTGGGCTCTCACGG
GAGTACAAACTAGTGATGCTGGGTGCTGGTGGTGTAGGGAAGAGTGCCATGACCATGCAG
TTCATCAGCCACCGATTCCCAGAAGATCATGATCCCACCATTGAAGATGCTTATAAGATC
AGGATCCGTATTGATGATGAGCCTGCCAATCTGGACATTTTGGATACAGCTGGACAGGCA
GAGTTTACAGCCATGCGGGACCAGTATATGAGGGCAGGAGAAGGGTTTATCATCTGTTAC
TCTATCACGGATCGTCGAAGTTTCCATGAAGTTCGAGAGTTTAAACAGCTTATTTATCGA
GTCCGACGTACTGACGATACACCTGTGGTTCTTGTGGGAAACAAGTCAGACCTCAAACAG
CTAAGACAGGTCACCAAGGAAGAAGGATTGGCCTTGGCCCGAGAATTCAGCTGTCCCTTT
TTTGAGACATCTGCTGCATACCGCTACTATATTGATGATGTTTTCCATGCCCTTGTACGG
GAGATACGTAGGAAAGAAAAGGAGGCAGTACTGGCCATGGAGAAAAAATCTAAGCCCAAA
AACAGTGTATGGAAGAGGCTAAAATCACCATTCCGGAAGAAGAAAGATTCAGTAACTTGA

Protein Properties

Number of Residues

219

Molecular Weight

25144.6

Theoretical pI

9.5

Pfam Domain Function

Ras (PF00071 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>GTP-binding protein Rit1
MDSGTRPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKI
RIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYR
VRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVR
EIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT

External Links

GenBank ID Protein

4234918

UniProtKB/Swiss-Prot ID

Q92963

UniProtKB/Swiss-Prot Entry Name

RIT1_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF084462

GeneCard ID