| Identification |
|---|
| HMDB Protein ID
| CDBP03765 |
| Secondary Accession Numbers
| Not Available |
| Name
| Rhophilin-1 |
| Description
| Not Available |
| Synonyms
|
- GTP-Rho-binding protein 1
|
| Gene Name
| RHPN1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transduction |
| Specific Function
| Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| binding |
| protein binding |
| Process |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| biological regulation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:8 |
| Locus
| 8q24.3 |
| SNPs
| RHPN1 |
| Gene Sequence
|
>2088 bp
ATGATCCTGGAGGAGAGGCCGGACGGCGCGGGCGCCGGCGAGGAGAGCCCGCGGCTGCAG
GGCTGTGACTCCCTGACGCAGATCCAGTGCGGCCAGCTGCAGAGCCGCAGGGCCCAGATT
CACCAGCAGATTGACAAGGAGCTGCAGATGCGGACGGGCGCTGAGAACCTCTACAGAGCC
ACCAGCAACAACCGGGTGAGAGAGACGGTCGCCCTGGAGCTGAGCTACGTCAACTCCAAC
CTGCAGCTGCTGAAGGAGGAGCTGGAGGAGCTCAGCGGTGGCGTGGACCCTGGCCGGCAT
GGGAGCGAAGCTGTCACTGTCCCCATGATCCCCCTGGGCCTGAAGGAGACCAAGGAGCTG
GACTGGTCTACACCGCTGAAGGAGCTGATCTCAGTGCACTTTGGAGAGGACGGCGCCTCC
TACGAGGCAGAAATCAGGGAGCTGGAGGCCCTGCGGCAGGCCATGCGGACCCCCAGCCGG
AATGAGTCGGGCCTGGAGCTGCTCACAGCCTATTACAACCAGCTGTGCTTCCTGGATGCG
CGCTTCCTCACCCCTGCCAGGAGCCTCGGGCTCTTCTTCCACTGGTACGACTCGCTTACT
GGGGTCCCGGCCCAGCAGCGTGCCCTGGCCTTCGAGAAGGGCAGCGTTCTCTTCAACATC
GGTGCCCTCCACACGCAGATTGGGGCGCGCCAGGACCGCTCCTGCACCGAGGGTGCCCGC
CGCGCTATGGAGGCCTTCCAGAGGGCCGCTGGGGCCTTCAGCCTCCTGAGGGAGAACTTC
TCCCATGCGCCGAGCCCAGACATGAGCGCTGCGTCCCTCTGCGCACTGGAGCAGCTCATG
ATGGCCCAGGCCCAGGAATGTGTGTTTGAGGGCCTCTCACCACCTGCCTCCATGGCCCCC
CAAGACTGCCTGGCCCAGCTGCGCCTGGCGCAGGAGGCCGCCCAGGTGGCAGCCGAGTAC
AGGCTAGTGCACCGGACCATGGCCCAGCCACCCGTCCACGACTACGTGCCTGTCTCCTGG
ACTGCCCTGGTGCATGTCAAGGCCGAGTACTTCCGCTCCCTGGCCCACTACCACGTAGCC
ATGGCCCTCTGCGACGGCTCCCGTGAGTGCCCACCACACTTGCCCATGGTACTGCCAAGG
CCCCCCCGCGCAGGCTCACAGCCTCTCTGTCCCCCAGCAGCGACCGAGGGAGAGCTCCCC
ACGCACGAGCAGGTCTTCCTGCAGCCCCCCACCTCCTCTAAGCCCCGAGGCCCTGTGCTG
CCGCAGGAGCTGGAGGAGCGCAGGCAGCTTGGCAAGGCACACCTGAAGCGTGCCATCCTG
GGGCAGGAGGAGGCGCTGCGGCTGCACGCCCTGTGCCGCGTCCTGCGCGAGGTGGACCTG
CTTCGGGCTGTGATCTCCCAGACGCTGCAGCGCTCACTGGCCAAGTATGCGGAGCTCGAC
CGTGAGGATGACTTCTGTGAGGCTGCCGAGGCCCCGGACATCCAGCCTAAGACCCACCAG
AAGCCAGAGGCCAGGATGCCACGCCTGTCCCAGGGGAAGGGGCCTGACATCTTCCATCGG
CTGGGGCCCCTGTCTGTGTTCTCAGCCAAGAACCGGTGGCGGCTGGTGGGGCCCGTCCAC
CTGACCCGAGGAGAGGGCGGCTTTGGCCTCACGCTTCGGGGAGACTCGCCTGTCCTCATC
GCTGCCGTCATTCCAGGGAGCCAGGCCGCGGCGGCTGGCCTGAAGGAGGGCGACTACATT
GTGTCAGTGAATGGGCAGCCATGCAGGTGGTGGAGACACGCGGAGGTGGTGACGGAGCTG
AAGGCTGCGGGAGAGGCGGGCGCCAGCCTGCAGGTGGTGTCGCTGCTGCCCAGCTCTAGA
CTGCCCAGCTTGGGGGACCGCCGGCCCGTCCTGCTGGGCCCCAGGGGGCTTCTAAGGAGC
CAGAGGGAGCATGGTTGCAAGACCCCGGCATCCACGTGGGCCAGTCCCCGGCCCCTCCTC
AACTGGAGCCGAAAGGCCCAGCAGGGCAAGACTGGAGGCTGCCCCCAGCCCTGTGCCCCA
GTGAAGCCAGCTCCGCCCTCATCCTTGAAGCACCCAGGGTGGCCGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 695 |
| Molecular Weight
| 76291.4 |
| Theoretical pI
| 7.82 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Rhophilin-1
MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRA
TSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKEL
DWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDA
RFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGAR
RAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAP
QDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVA
MALCDGSRECPPHLPMVLPRPPRAGSQPLCPPAATEGELPTHEQVFLQPPTSSKPRGPVL
PQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELD
REDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVH
LTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTEL
KAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLL
NWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP
|
| External Links |
|---|
| GenBank ID Protein
| 19697913 |
| UniProtKB/Swiss-Prot ID
| Q8TCX5 |
| UniProtKB/Swiss-Prot Entry Name
| RHPN1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY082588 |
| GeneCard ID
| RHPN1 |
| GenAtlas ID
| RHPN1 |
| HGNC ID
| HGNC:19973 |
| References |
|---|
| General References
| Not Available |