Identification |
HMDB Protein ID
| CDBP03764 |
Secondary Accession Numbers
| Not Available |
Name
| Rho-related GTP-binding protein RhoJ |
Description
| Not Available |
Synonyms
|
- Ras-like protein family member 7B
- Tc10-like GTP-binding protein
|
Gene Name
| RHOJ |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTP binding |
Specific Function
| GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology |
GO Classification
|
Component |
cell part |
intracellular |
Function |
purine nucleotide binding |
binding |
nucleotide binding |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
Process |
regulation of biological process |
regulation of cellular process |
signal transduction |
intracellular signal transduction |
small gtpase mediated signal transduction |
biological regulation |
|
Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasmic side (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 14q23.2 |
SNPs
| RHOJ |
Gene Sequence
|
>645 bp
ATGAACTGCAAAGAGGGAACTGACAGCAGCTGCGGCTGCAGGGGCAACGACGAGAAGAAG
ATGTTGAAGTGTGTGGTGGTGGGGGACGGTGCCGTGGGGAAAACCTGCCTGCTGATGAGC
TACGCCAACGACGCCTTCCCAGAGGAATACGTGCCCACTGTGTTTGACCACTATGCAGTT
ACTGTGACTGTGGGAGGCAAGCAACACTTGCTCGGACTGTATGACACCGCGGGACAGGAG
GACTACAACCAGCTGAGGCCACTCTCCTACCCCAACACGGATGTGTTTTTGATCTGCTTC
TCTGTCGTAAACCCTGCCTCTTACCACAATGTCCAGGAGGAATGGGTCCCCGAGCTCAAG
GACTGCATGCCTCACGTGCCTTATGTCCTCATAGGGACCCAGATTGATCTCCGTGATGAC
CCAAAAACCTTGGCCCGTTTGCTGTATATGAAAGAGAAACCTCTCACTTACGAGCATGGT
GTGAAGCTCGCAAAAGCGATCGGAGCACAGTGCTACTTGGAATGTTCAGCTCTGACTCAG
AAAGGTCTCAAAGCGGTTTTTGATGAAGCAATCCTCACCATTTTCCACCCCAAGAAAAAG
AAGAAACGCTGTTCTGAGGGTCACAGCTGCTGTTCAATTATCTGA
|
Protein Properties |
Number of Residues
| 214 |
Molecular Weight
| 23820.3 |
Theoretical pI
| 6.83 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Rho-related GTP-binding protein RhoJ
MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAV
TVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELK
DCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQ
KGLKAVFDEAILTIFHPKKKKKRCSEGHSCCSII
|
External Links |
GenBank ID Protein
| 9968292 |
UniProtKB/Swiss-Prot ID
| Q9H4E5 |
UniProtKB/Swiss-Prot Entry Name
| RHOJ_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AJ276567 |
GeneCard ID
| RHOJ |
GenAtlas ID
| RHOJ |
HGNC ID
| HGNC:688 |
References |
General References
| Not Available |