Identification
HMDB Protein ID CDBP03764
Secondary Accession Numbers Not Available
Name Rho-related GTP-binding protein RhoJ
Description Not Available
Synonyms
  1. Ras-like protein family member 7B
  2. Tc10-like GTP-binding protein
Gene Name RHOJ
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology
GO Classification
Component
cell part
intracellular
Function
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Process
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
biological regulation
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasmic side (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 14q23.2
SNPs RHOJ
Gene Sequence
>645 bp
ATGAACTGCAAAGAGGGAACTGACAGCAGCTGCGGCTGCAGGGGCAACGACGAGAAGAAG
ATGTTGAAGTGTGTGGTGGTGGGGGACGGTGCCGTGGGGAAAACCTGCCTGCTGATGAGC
TACGCCAACGACGCCTTCCCAGAGGAATACGTGCCCACTGTGTTTGACCACTATGCAGTT
ACTGTGACTGTGGGAGGCAAGCAACACTTGCTCGGACTGTATGACACCGCGGGACAGGAG
GACTACAACCAGCTGAGGCCACTCTCCTACCCCAACACGGATGTGTTTTTGATCTGCTTC
TCTGTCGTAAACCCTGCCTCTTACCACAATGTCCAGGAGGAATGGGTCCCCGAGCTCAAG
GACTGCATGCCTCACGTGCCTTATGTCCTCATAGGGACCCAGATTGATCTCCGTGATGAC
CCAAAAACCTTGGCCCGTTTGCTGTATATGAAAGAGAAACCTCTCACTTACGAGCATGGT
GTGAAGCTCGCAAAAGCGATCGGAGCACAGTGCTACTTGGAATGTTCAGCTCTGACTCAG
AAAGGTCTCAAAGCGGTTTTTGATGAAGCAATCCTCACCATTTTCCACCCCAAGAAAAAG
AAGAAACGCTGTTCTGAGGGTCACAGCTGCTGTTCAATTATCTGA
Protein Properties
Number of Residues 214
Molecular Weight 23820.3
Theoretical pI 6.83
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Rho-related GTP-binding protein RhoJ
MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAV
TVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELK
DCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQ
KGLKAVFDEAILTIFHPKKKKKRCSEGHSCCSII
GenBank ID Protein 9968292
UniProtKB/Swiss-Prot ID Q9H4E5
UniProtKB/Swiss-Prot Entry Name RHOJ_HUMAN
PDB IDs Not Available
GenBank Gene ID AJ276567
GeneCard ID RHOJ
GenAtlas ID RHOJ
HGNC ID HGNC:688
References
General References Not Available