Showing Protein GTP-binding protein Rhes (CDBP03760)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03760
Secondary Accession Numbers Not Available
Name GTP-binding protein Rhes
Description Not Available
Synonyms
  1. Ras homolog enriched in striatum
  2. Tumor endothelial marker 2
Gene Name RASD2
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination
GO Classification
Component
membrane
cell part
intracellular
Function
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 22q13.1
SNPs RASD2
Gene Sequence 
>801 bp
ATGATGAAGACTTTGTCCAGCGGGAACTGCACGCTCAGTGTGCCCGCCAAAAACTCATAC
CGCATGGTGGTGCTGGGTGCCTCTCGGGTGGGCAAGAGCTCCATCGTGTCTCGCTTCCTC
AATGGCCGCTTTGAGGACCAGTACACACCCACCATCGAGGACTTCCACCGTAAGGTATAC
AACATCCGCGGCGACATGTACCAGCTCGACATCCTGGATACCTCTGGCAACCACCCCTTC
CCCGCCATGCGCAGGCTGTCCATCCTCACAGGGGATGTCTTCATCCTGGTGTTCAGCCTG
GATAACCGGGAGTCCTTCGATGAGGTCAAGCGCCTTCAGAAGCAGATCCTGGAGGTCAAG
TCCTGCCTGAAGAACAAGACCAAGGAGGCGGCGGAGCTGCCCATGGTCATCTGTGGCAAC
AAGAACGACCACGGCGAGCTGTGCCGCCAGGTGCCCACCACCGAGGCCGAGCTGCTGGTG
TCGGGCGACGAGAACTGCGCCTACTTCGAGGTGTCGGCCAAGAAGAACACCAACGTGGAC
GAGATGTTCTACGTGCTCTTCAGCATGGCCAAGCTGCCACACGAGATGAGCCCCGCCCTG
CATCGCAAGATCTCCGTGCAGTACGGTGACGCCTTCCACCCCAGGCCCTTCTGCATGCGC
CGCGTCAAGGAGATGGACGCCTATGGCATGGTCTCGCCCTTCGCCCGCCGCCCCAGCGTC
AACAGTGACCTCAAGTACATCAAGGCCAAGGTCCTTCGGGAAGGCCAGGCCCGTGAGAGG
GACAAGTGCACCATCCAGTGA
Protein Properties
Number of Residues 266
Molecular Weight 30365.8
Theoretical pI 9.18
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>GTP-binding protein Rhes
MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY
NIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVK
SCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVD
EMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARRPSV
NSDLKYIKAKVLREGQARERDKCTIQ
GenBank ID Protein 22027486
UniProtKB/Swiss-Prot ID Q96D21
UniProtKB/Swiss-Prot Entry Name RHES_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_014310.3
GeneCard ID RASD2
GenAtlas ID RASD2
HGNC ID HGNC:18229
References
General References Not Available