Showing Protein Ras-specific guanine nucleotide-releasing factor 1 (CDBP03758)
| Identification | |||||||||||||||||||||||||||
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| HMDB Protein ID | CDBP03758 | ||||||||||||||||||||||||||
| Secondary Accession Numbers | Not Available | ||||||||||||||||||||||||||
| Name | Ras-specific guanine nucleotide-releasing factor 1 | ||||||||||||||||||||||||||
| Description | Not Available | ||||||||||||||||||||||||||
| Synonyms |
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| Gene Name | RASGRF1 | ||||||||||||||||||||||||||
| Protein Type | Enzyme | ||||||||||||||||||||||||||
| Biological Properties | |||||||||||||||||||||||||||
| General Function | Involved in Rho guanyl-nucleotide exchange factor activity | ||||||||||||||||||||||||||
| Specific Function | Promotes the exchange of Ras-bound GDP by GTP | ||||||||||||||||||||||||||
| GO Classification |
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| Cellular Location | Not Available | ||||||||||||||||||||||||||
| Pathways | Not Available | ||||||||||||||||||||||||||
| Gene Properties | |||||||||||||||||||||||||||
| Chromosome Location | Chromosome:1 | ||||||||||||||||||||||||||
| Locus | 15q24.2 | ||||||||||||||||||||||||||
| SNPs | RASGRF1 | ||||||||||||||||||||||||||
| Gene Sequence |
>3828 bp ATGCAGAAAGCCATCCGACTTAATGATGGCCACGTCGCGCCCCTGGGACTGCTGGCGCGC AAGGACGGCACGCGCAAAGGCTACCTGAGCAAGCGGAGTTCGGACAACACAAAATGGCAA ACCAAGTGGTTCGCGCTGCTGCAGAACCTGCTCTTCTACTTCGAGAGCGACTCGAGCTCG CGGCCCTCGGGGCTTTACCTGCTGGAGGGCTGCGTCTGCGACCGCGCGCCCTCCCCCAAG CCGGCGCTGTCGGCCAAGGAGCCGCTGGAGAAACAGCATTACTTCACGGTGAACTTCAGC CATGAGAACCAGAAAGCCTTGGAGCTGAGGACAGAGGACGCAAAAGATTGTGACGAATGG GTGGCAGCCATTGCACATGCCAGCTACAGGACCCTCGCCACAGAGCATGAGGCATTAATG CAGAAATACCTGCACCTGCTGCAGATCGTGGAGACAGAGAAGACCGTGGCCAAGCAGCTT CGGCAGCAGATCGAGGATGGGGAGATCGAGATCGAGCGGCTGAAGGCAGAGATCACATCC CTGCTCAAGGACAATGAGCGCATCCAGTCCACCCAGACTGTCGCCCCCAACGATGAAGAC AGCGACATCAAGAAAATTAAGAAGGTGCAGAGCTTCCTGCGGGGCTGGCTGTGCCGGCGG AAGTGGAAGACCATCATCCAGGACTACATCCGGTCACCCCATGCTGACAGCATGCGCAAG AGGAACCAGGTGGTGTTCAGCATGCTGGAGGCTGAGGCTGAGTACGTGCAGCAGCTGCAC ATCCTTGTCAACAATTTCCTGCGCCCGCTGCGGATGGCCGCCAGCTCCAAGAAGCCTCCC ATCACACACGACGACGTCAGCAGCATCTTCCTGAACAGCGAAACCATCATGTTTTTACAT CAGATCTTTTACCAAGGCCTGAAGGCCCGCATCTCCAGCTGGCCCACGCTGGTCCTGGCT GACCTACTTGACATCCTGCTGCCCATGCTCAACATCTACCAAGAGTTCGTCCGCAACCAC CAGTACAGCCTGCAGATCCTGGCCCACTGCAAGCAGAACCGTGACTTCGACAAGCTGCTG AAGCACTACGAGGCCAAGCCTGACTGCGAGGAGAGGACGTTGGAGACCTTCCTCACCTAC CCCATGTTCCAGATCCCCAGGTACATCCTGACCCTCCATGACGTCCTGGCCCACACGCCT CATGAGCACGTTGAGCGCAACAGCCTGGACTACGCCAAGTCCAAACTGGAGGAGCTGTCC AGAATAATGCACGATGAAGTAAGTGAGACGGAGAACATCCGGAAAAACCTGGCCATCGAG CGCATGATCATCGAAGGCTGTGAGATCCTCCTGGACACCAGCCAGACCTTTGTGAGACAA GGTTCCCTCATTCAGGTGCCCATGTCTGAAAAGGGCAAGATCACCAGGGGGCGCCTGGGG TCTCTCTCCCTAGAGAAAGAGGGCGAGCGACAGTGCTTCCTGTTTTCTAAGCATCTGATT ATCTGTACCAGAGGCTCTGGAGGGAAGCTTCACTTGACCAAGAATGGAGTCATATCCCTC ATTGACTGCACTTTATTGGAGGAGCCAGAAAGCACGGAGGAGGAAGCCAAAGGATCCGGC CAAGACATAGATCACTTGGATTTCAAAATCGGGGTGGAGCCAAAGGATTCCCCGCCCTTT ACAGTCATCCTAGTGGCCTCGTCCAGACAGGAGAAGGCAGCGTGGACCAGTGACATCAGC CAGTGTGTGGATAACATCCGATGCAATGGGCTCATGATGAACGCATTTGAAGAAAATTCC AAGGTCACTGTGCCGCAGATGATCAAGAGGACCAGGGAGGGGACCAGGGAAGCAGAAATG AGCAGGTCCGACGCCTCCTTATATTGTGATGATGTTGACATTCGCTTCAGCAAAACCATG AACTCCTGCAAAGTGCTGCAGATCCGCTACGCCAGTGTGGAGCGGCTGCTGGAGAGGCTG ACGGACCTGCGCTTCCTGAGCATCGACTTCCTCAACACCTTCCTGCACTCCTACCGCGTC TTCACCACCGCCATCGTGGTCCTGGACAAGCTCATTACCATCTACAAGAAGCCTATCAGT GCCATTCCTGCCAGGTGGCTGAGGTCGCTGGAGCTCCTGTTTGCCAGTGGCCAGAACAAT AAGCTCCTGTACGGTGAACCCCCCAAGTCCCCGCGCGCCACCCGCAAGTTCTCCTCGCCG CCACCTCTGTCCATCACCAAGACATCGTCACCGAGCCGCCGGCGGAAGCTGATCTCCCTG AACATCCCCATCATCACTGGCGGCAAGGCCCTGGACCTGGCCGGATCCCTCAGCTGCAAC TCCAATGGCTACACCAGCATGTACTCGGCCATGTCACCCTTCAGCAAGGCCACGCTGGAC ACCAGCAAGCTCTATGTGTCCAGCAGCTTCACCAACAAGATTCCAGATGAGGGCGATACG ACCCCTGAGAAGCCCGAAGACCCTTCAGCGCTCAGCAAGCAGAGCTCAGAAGTCTCCATG AGAGAGGAGTCAGATATTGATCAAAACCAGAGTGATGATGGTGATACTGAAACATCACCA ACTAAATCTCCAACAACACCCAAATCAGTCAAAAACAAAAATTCTTCAGAGTTCCCACTC TTTTCCTATAACAATGGAGTCGTCATGACCTCCTGTCGTGAACTGGACAATAACCGCAGT GCCTTGTCGGCCGCCTCTGCCTTTGCCATAGCAACCGCCGGGGCCAACGAGGGCACCCCA AACAAGGAGAAGTACCGGAGGATGTCCTTAGCCAGTGCAGGGTTTCCCCCAGACCAGAGG AATGGAGACAAGGAGTTTGTGATCCGCAGAGCAGCCACCAATCGTGTCTTGAACGTGCTC CGCCACTGGGTGTCCAAGCACTCTCAGGACTTTGAGACCAACGATGAGCTCAAATGCAAG GTGATCGGCTTCCTGGAAGAAGTCATGCACGACCCGGAGCTCCTGACCCAGGAGCGGAAA GCTGCAGCCAACATCATCAGGACTCTGACCCAGGAGGACCCAGGTGACAACCAGATCACG CTGGAGGAGATCACGCAGATGGCTGAAGGCGTGAAGGCTGAGCCCTTTGAAAACCACTCA GCCCTGGAGATCGCGGAGCAGCTGACCCTGCTGGATCACCTCGTCTTCAAGAAGATTCCT TATGAGGAGTTCTTCGGACAAGGATGGATGAAACTGGAAAAGAATGAAAGGACCCCTTAT ATCATGAAAACCACTAAGCACTTCAATGACATCAGTAACTTGATTGCTTCAGAAATCATC CGCAATGAGGACATCAACGCCAGGGTGAGCGCCATCGAGAAGTGGGTGGCCGTAGCTGAC ATATGCCGCTGCCTCCACAACTACAATGCCGTACTGGAGATCACCTCGTCCATGAACCGC AGTGCAATCTTCCGGCTCAAAAAGACGTGGCTCAAAGTCTCTAAGCAGACTAAAGCTTTG ATTGATAAGCTCCAAAAGCTTGTGTCATCAGAGGGCAGATTTAAGAATCTCAGAGAAGCT CTGAAAAATTGTGACCCACCCTGTGTCCCTTACCTGGGGATGTACCTCACCGACCTGGCC TTCATCGAGGAGGGGACGCCCAATTACACGGAAGACGGCCTGGTCAACTTCTCCAAGATG AGGATGATATCCCATATTATCCGAGAGATTCGCCAGTTTCAACAAACTGCCTACAAAATA GAGCACCAAGCAAAGGTAACGCAATATTTACTGGACCAATCTTTTGTAATGGATGAAGAA AGCCTCTACGAGTCTTCTCTCCGAATAGAACCAAAACTCCCCACCTGA |
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| Protein Properties | |||||||||||||||||||||||||||
| Number of Residues | 1275 | ||||||||||||||||||||||||||
| Molecular Weight | 145381.4 | ||||||||||||||||||||||||||
| Theoretical pI | 7.3 | ||||||||||||||||||||||||||
| Pfam Domain Function | |||||||||||||||||||||||||||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Ras-specific guanine nucleotide-releasing factor 1 MQKAIRLNDGHVAPLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH QIFYQGLKARISSWPTLVLADLLDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHDVLAHTPHEHVERNSLDYAKSKLEELS RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG SLSLEKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS KVTVPQMIKRTREGTREAEMSRSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNN KLLYGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLISLNIPIITGGKALDLAGSLSCN SNGYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSM REESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRS ALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVL RHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQIT LEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPY IMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNR SAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLA FIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEE SLYESSLRIEPKLPT |
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| External Links | |||||||||||||||||||||||||||
| GenBank ID Protein | 433720 | ||||||||||||||||||||||||||
| UniProtKB/Swiss-Prot ID | Q13972 | ||||||||||||||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | RGRF1_HUMAN | ||||||||||||||||||||||||||
| PDB IDs | Not Available | ||||||||||||||||||||||||||
| GenBank Gene ID | L26584 | ||||||||||||||||||||||||||
| GeneCard ID | RASGRF1 | ||||||||||||||||||||||||||
| GenAtlas ID | RASGRF1 | ||||||||||||||||||||||||||
| HGNC ID | HGNC:9875 | ||||||||||||||||||||||||||
| References | |||||||||||||||||||||||||||
| General References | Not Available | ||||||||||||||||||||||||||