Showing Protein Ral guanine nucleotide dissociation stimulator-like 3 (CDBP03756)
| Identification | |||||||||||||||||||
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| HMDB Protein ID | CDBP03756 | ||||||||||||||||||
| Secondary Accession Numbers | Not Available | ||||||||||||||||||
| Name | Ral guanine nucleotide dissociation stimulator-like 3 | ||||||||||||||||||
| Description | Not Available | ||||||||||||||||||
| Synonyms |
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| Gene Name | RGL3 | ||||||||||||||||||
| Protein Type | Enzyme | ||||||||||||||||||
| Biological Properties | |||||||||||||||||||
| General Function | Involved in signal transduction | ||||||||||||||||||
| Specific Function | Guanine nucleotide exchange factor (GEF) for Ral-A. Potential effector of GTPase HRas and Ras-related protein M-Ras. Negatively regulates Elk-1-dependent gene induction downstream of HRas and MEKK1 | ||||||||||||||||||
| GO Classification |
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| Cellular Location | Not Available | ||||||||||||||||||
| Pathways | Not Available | ||||||||||||||||||
| Gene Properties | |||||||||||||||||||
| Chromosome Location | Chromosome:1 | ||||||||||||||||||
| Locus | 19p13.2 | ||||||||||||||||||
| SNPs | RGL3 | ||||||||||||||||||
| Gene Sequence |
>2133 bp ATGGAGCGCACAGCAGGCAAAGAGCTGGCCCTGGCACCGCTGCAGGACTGGGGTGAAGAG ACCGAGGACGGCGCGGTGTACAGTGTCTCCCTGCGGCGGCAGCGCAGTCAGCGCAGGAGC CCGGCGGAGGGCCCCGGGGGCAGCCAGGCTCCCAGCCCCATTGCCAATACCTTCCTCCAC TATCGAACCAGCAAGGTGAGGGTGCTGAGGGCAGCGCGCCTGGAGCGGCTGGTGGGAGAG TTGGTGTTTGGAGACCGTGAGCAGGACCCCAGCTTCATGCCCGCCTTCCTGGCCACCTAC CGGACCTTTGTACCCACTGCCTGCCTGCTGGGCTTTCTGCTGCCACCAATGCCACCGCCC CCACCTCCCGGGGTAGAGATCAAGAAGACAGCGGTACAAGATCTGAGCTTCAACAAGAAC CTGAGGGCTGTGGTGTCAGTGCTGGGCTCCTGGCTGCAGGACCACCCTCAGGATTTCCGA GACCCCCCTGCCCATTCGGACCTGGGCAGTGTCCGAACCTTTCTGGGCTGGGCGGCCCCA GGGAGTGCTGAGGCTCAAAAAGCAGAGAAGCTTCTGGAAGATTTTTTGGAGGAGGCTGAG CGAGAGCAGGAAGAGGAGCCGCCTCAGGTGTGGACAGGACCTCCCAGAGTTGCCCAAACT TCTGACCCAGACTCTTCAGAGGCCTGCGCGGAGGAAGAGGAAGGGCTCATGCCTCAAGGT CCCCAGCTCCTGGACTTCAGCGTGGACGAGGTGGCCGAGCAGCTGACCCTCATAGACTTG GAGCTCTTCTCCAAGGTGAGGCTCTACGAGTGCTTGGGCTCCGTGTGGTCGCAGAGGGAC CGGCCGGGGGCTGCAGGCGCCTCCCCCACTGTGCGCGCCACCGTGGCCCAGTTCAACACC GTGACCGGCTGTGTGCTGGGTTCCGTGCTCGGAGCACCGGGCTTGGCCGCCCCGCAGAGG GCGCAGCGGCTGGAGAAGTGGATCCGCATCGCCCAGCGCTGCCGAGAACTGCGGAACTTC TCCTCCTTGCGCGCCATCCTGTCCGCCCTGCAATCTAACCCCATCTACCGGCTCAAGCGC AGCTGGGGGGCAGTGAGCCGGGAACCGCTATCTACTTTCAGGAAACTTTCGCAGATTTTC TCCGATGAGAACAACCACCTCAGCAGCAGAGAGATTCTTTTCCAGGAGGAGGCCACTGAG GGATCCCAAGAAGAGGACAACACCCCAGGCAGCCTGCCCTCAAAACCACCCCCAGGCCCT GTCCCCTACCTTGGCACCTTCCTTACGGACCTGGTTATGCTGGACACAGCCCTGCCGGAT ATGTTGGAGGGGGATCTCATTAACTTTGAGAAGAGGAGGAAGGAGTGGGAGATCCTGGCC CGCATCCAGCAGCTGCAGAGGCGCTGTCAGAGCTACACCCTGAGCCCCCACCCGCCCATC CTGGCTGCCCTGCATGCCCAGAACCAGCTCACCGAGGAGCAGAGCTACCGGCTCTCCCGG GTCATTGAGCCACCAGCTGCCTCCTGCCCCAGCTCCCCACGCATCCGACGGCGGATCAGC CTCACCAAGCGTCTCAGTGCGAAGCTTGCCCGAGAGAAAAGCTCATCACCTAGTGGGAGT CCCGGGGACCCCTCATCCCCCACCTCCAGTGTGTCCCCAGGGTCACCCCCCTCAAGTCCT AGAAGCAGAGATGCTCCTGCTGGCAGTCCCCCGGCCTCTCCAGGGCCCCAGGGCCCCAGC ACCAAGCTGCCCCTGAGCCTGGACCTGCCCAGCCCCCGGCCCTTCGCTTTGCCTCTGGGC AGCCCTCGAATCCCCCTCCCGGCGCAGCAGAGCTCGGAGGCCCGTGTCATCCGCGTCAGC ATCGACAATGACCACGGGAACCTGTATCGAAGCATCTTGCTGACCAGTCAGGACAAAGCC CCCAGCGTGGTCCGGCGAGCCTTGCAGAAGCACAATGTGCCCCAGCCCTGGGCCTGTGAC TATCAGCTCTTTCAAGTCCTTCCTGGGGACCGGGTGCTCCTGATTCCTGACAATGCCAAC GTCTTCTATGCCATGAGTCCAGTCGCCCCCAGAGACTTCATGCTGCGGCGGAAAGAGGGG ACCCGGAACACTCTGTCTGTCTCCCCAAGCTGA |
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| Protein Properties | |||||||||||||||||||
| Number of Residues | 710 | ||||||||||||||||||
| Molecular Weight | 78078.5 | ||||||||||||||||||
| Theoretical pI | 7.76 | ||||||||||||||||||
| Pfam Domain Function | |||||||||||||||||||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Ral guanine nucleotide dissociation stimulator-like 3 MERTAGKELALAPLQDWGEETEDGAVYSVSLRRQRSQRRSPAEGPGGSQAPSPIANTFLH YRTSKVRVLRAARLERLVGELVFGDREQDPSFMPAFLATYRTFVPTACLLGFLLPPMPPP PPPGVEIKKTAVQDLSFNKNLRAVVSVLGSWLQDHPQDFRDPPAHSDLGSVRTFLGWAAP GSAEAQKAEKLLEDFLEEAEREQEEEPPQVWTGPPRVAQTSDPDSSEACAEEEEGLMPQG PQLLDFSVDEVAEQLTLIDLELFSKVRLYECLGSVWSQRDRPGAAGASPTVRATVAQFNT VTGCVLGSVLGAPGLAAPQRAQRLEKWIRIAQRCRELRNFSSLRAILSALQSNPIYRLKR SWGAVSREPLSTFRKLSQIFSDENNHLSSREILFQEEATEGSQEEDNTPGSLPSKPPPGP VPYLGTFLTDLVMLDTALPDMLEGDLINFEKRRKEWEILARIQQLQRRCQSYTLSPHPPI LAALHAQNQLTEEQSYRLSRVIEPPAASCPSSPRIRRRISLTKRLSAKLAREKSSSPSGS PGDPSSPTSSVSPGSPPSSPRSRDAPAGSPPASPGPQGPSTKLPLSLDLPSPRPFALPLG SPRIPLPAQQSSEARVIRVSIDNDHGNLYRSILLTSQDKAPSVVRRALQKHNVPQPWACD YQLFQVLPGDRVLLIPDNANVFYAMSPVAPRDFMLRRKEGTRNTLSVSPS |
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| External Links | |||||||||||||||||||
| GenBank ID Protein | 239582763 | ||||||||||||||||||
| UniProtKB/Swiss-Prot ID | Q3MIN7 | ||||||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | RGL3_HUMAN | ||||||||||||||||||
| PDB IDs | Not Available | ||||||||||||||||||
| GenBank Gene ID | NM_001035223.2 | ||||||||||||||||||
| GeneCard ID | RGL3 | ||||||||||||||||||
| GenAtlas ID | RGL3 | ||||||||||||||||||
| HGNC ID | HGNC:30282 | ||||||||||||||||||
| References | |||||||||||||||||||
| General References | Not Available | ||||||||||||||||||