Showing Protein GTPase RhebL1 (CDBP03748)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03748
Secondary Accession Numbers Not Available
Name GTPase RhebL1
Description Not Available
Synonyms
  1. Ras homolog enriched in brain like-1 c
  2. Ras homolog enriched in brain-like protein 1
  3. Rheb-like protein 1
  4. Rheb2
  5. RhebL1c
Gene Name RHEBL1
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2
GO Classification
Component
membrane
cell part
intracellular
Function
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasm
  4. Cytoplasmic side
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q13.12
SNPs RHEBL1
Gene Sequence 
>552 bp
ATGCCGCTAGTCCGCTACAGGAAGGTGGTCATCCTCGGATACCGCTGTGTAGGGAAGACA
TCTTTGGCACATCAATTTGTGGAAGGCGAGTTCTCGGAAGGCTACGATCCTACAGTGGAG
AATACTTACAGCAAGATAGTGACTCTTGGCAAAGATGAGTTTCACCTACATCTGGTGGAC
ACAGCAGGGCAGGATGAGTACAGCATTCTGCCCTATTCATTCATCATTGGGGTCCATGGT
TATGTGCTTGTGTATTCTGTCACCTCTCTGCATAGCTTCCAAGTCATTGAGAGTCTGTAC
CAAAAGCTACATGAAGGCCATGGGAAAACCCGGGTGCCAGTGGTTCTAGTGGGGAACAAG
GCAGATCTCTCTCCAGAGAGAGAGGTACAGGCAGTTGAAGGAAAGAAGCTGGCAGAGTCC
TGGGGTGCGACATTTATGGAGTCATCTGCTCGAGAGAATCAGCTGACTCAAGGCATCTTC
ACCAAAGTCATCCAGGAGATTGCCCGTGTGGAGAATTCCTATGGGCAAGAGCGTCGCTGC
CATCTCATGTGA
Protein Properties
Number of Residues 183
Molecular Weight 20681.5
Theoretical pI 6.72
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>GTPase RhebL1
MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
HLM
GenBank ID Protein 21758740
UniProtKB/Swiss-Prot ID Q8TAI7
UniProtKB/Swiss-Prot Entry Name REBL1_HUMAN
PDB IDs Not Available
GenBank Gene ID AK098663
GeneCard ID RHEBL1
GenAtlas ID RHEBL1
HGNC ID HGNC:21166
References
General References Not Available