Cannabis Compound Database: Showing Protein GTPase KRas (CDBP03738)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03738

Secondary Accession Numbers

Not Available

Name

GTPase KRas

Description

Not Available

Synonyms

GTPase KRas, N-terminally processed
K-Ras 2
Ki-Ras
c-K-ras
c-Ki-ras

Gene Name

KRAS

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTP binding

Specific Function

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity

GO Classification

Component
membrane
cell part
intracellular
Function
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction

Cellular Location

Cell membrane
Lipid-anchor
Cytoplasmic side

Pathways

Name	SMPDB/Pathwhiz	KEGG
Fc Epsilon Receptor I Signaling in Mast Cells		Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

12p12.1

SNPs

KRAS

Gene Sequence

>567 bp
ATGACTGAATATAAACTTGTGGTAGTTGGAGCTTGTGGCGTAGGCAAGAGTGCCTTGACG
ATACAGCTAATTCAGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGATTCCTAC
AGGAAGCAAGTAGTAATTGATGGAGAAACCTGTCTCTTGGATATTCTCGACACAGCAGGT
CAAGAGGAGTACAGTGCAATGAGGGACCAGTACATGAGGACTGGGGAGGGCTTTCTTTGT
GTATTTGCCATAAATAATACTAAATCATTTGAAGATATTCACCATTATAGAGAACAAATT
AAAAGAGTTAAGGACTCTGAAGATGTACCTATGGTCCTAGTAGGAAATAAATGTGATTTG
CCTTCTAGAACAGTAGACACAAAACAGGCTCAGGACTTAGCAAGAAGTTATGGAATTCCT
TTTATTGAAACATCAGCAAAGACAAGACAGGGTGTTGATGATGCCTTCTATACATTAGTT
CGAGAAATTCGAAAACATAAAGAAAAGATGAGCAAAGATGGTAAAAAGAAGAAAAAGAAG
TCAAAGACAAAGTGTGTAATTATGTAA

Protein Properties

Number of Residues

189

Molecular Weight

21655.7

Theoretical pI

6.76

Pfam Domain Function

Ras (PF00071 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>GTPase KRas
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGC
VKIKKCIIM

External Links

GenBank ID Protein

186764

UniProtKB/Swiss-Prot ID

P01116

UniProtKB/Swiss-Prot Entry Name

RASK_HUMAN

PDB IDs

Not Available

GenBank Gene ID

M54968

GeneCard ID