| Identification |
|---|
| HMDB Protein ID
| CDBP03737 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ras association domain-containing protein 4 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RASSF4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transduction |
| Specific Function
| Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest |
| GO Classification
|
| Function |
| binding |
| protein binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10q11.21 |
| SNPs
| RASSF4 |
| Gene Sequence
|
>966 bp
ATGAAGGAAGACTGTCTGCCGAGTTCTCACGTGCCCATCAGTGACAGCAAGTCCATTCAG
AAGTCGGAGCTCTTAGGCCTGCTGAAAACCTACAACTGCTACCATGAGGGCAAGAGCTTC
CAGCTGAGACACCGTGAGGAAGAAGGGACTCTGATCATCGAGGGGCTCCTCAACATTGCC
TGGGGGCTGAGGCGGCCCATCCGGCTGCAGATGCAGGATGACCGGGAGCAGGTGCACCTC
CCCTCCACCTCATGGATGCCCAGACGGCCTAGCTGCCCTCTAAAGGAGCCATCGCCCCAG
AACGGGAACATCACAGCCAAGGGGCCAAGCATTCAGCCAGTGCACAAGGCTGAGAGTTCC
ACAGACAGCTCGGGGCCCCTGGAGGAGGCAGAGGAGGCCCCCCAGCTGATGCGGACCAAG
AGCGACGCCAGTTGCATGAGCCAGAGGAGGCCCAAGTGCCGCGCCCCCGGTGAGGCCCAG
CGCATCCGGCGACACCGGTTCTCTATCAACGGCCACTTCTACAATCATAAGACCTCCGTG
TTTACTCCAGCCTATGGATCCGTGACCAATGTGAGGGTCAACAGCACCATGACAACCCTG
CAGGTGCTCACCCTGCTGCTGAACAAATTTAGGGTGGAAGATGGCCCCAGTGAGTTCGCA
CTCTACATCGTTCACGAGTCTGGGGAGCGGACAAAATTAAAAGACTGCGAGTACCCGCTG
ATTTCCAGAATCCTGCATGGGCCATGTGAGAAGATCGCCAGGATCTTCCTGATGGAAGCT
GACTTGGGCGTGGAAGTCCCCCATGAAGTCGCTCAGTACATTAAGTTTGAAATGCCGGTG
CTGGACAGTTTTGTTGAAAAATTAAAAGAAGAGGAAGAAAGAGAAATAATCAAACTGACC
ATGAAGTTCCAAGCCCTGCGTCTGACGATGCTGCAGCGCCTGGAGCAGCTGGTGGAGGCC
AAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 321 |
| Molecular Weight
| 36747.9 |
| Theoretical pI
| 7.85 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ras association domain-containing protein 4
MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIA
WGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESS
TDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSV
FTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPL
ISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLT
MKFQALRLTMLQRLEQLVEAK
|
| External Links |
|---|
| GenBank ID Protein
| 12005908 |
| UniProtKB/Swiss-Prot ID
| Q9H2L5 |
| UniProtKB/Swiss-Prot Entry Name
| RASF4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF260335 |
| GeneCard ID
| RASSF4 |
| GenAtlas ID
| RASSF4 |
| HGNC ID
| HGNC:20793 |
| References |
|---|
| General References
| Not Available |