Cannabis Compound Database: Showing Protein GTPase ERas (CDBP03734)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03734

Secondary Accession Numbers

Not Available

Name

GTPase ERas

Description

Not Available

Synonyms

E-Ras
Embryonic stem cell-expressed Ras

Gene Name

ERAS

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTP binding

Specific Function

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells

GO Classification

Component
membrane
cell part
intracellular
Function
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction

Cellular Location

Cell membrane
Lipid-anchor
Cytoplasmic side

Pathways

Not Available

Gene Properties

Chromosome Location

Not Available

Locus

Not Available

SNPs

ERAS

Gene Sequence

>702 bp
ATGGAGCTGCCAACAAAGCCTGGCACCTTCGACCTGGGCCTGGCCACATGGAGCCCTTCC
TTCCAGGGGGAAACCCACCGGGCTCAGGCACGCCGCAGGGATGTTGGCAGGCAGCTGCCT
GAGTACAAGGCTGTGGTGGTGGGCGCCAGTGGCGTGGGCAAGAGTGCGCTGACCATCCAG
CTGAACCACCAGTGCTTCGTGGAGGACCACGACCCCACCATCCAGGATTCCTACTGGAAG
GAGTTGACCCTGGACAGTGGGGACTGCATTCTGAATGTGCTGGACACAGCAGGGCAGGCC
ATCCATAGGGCCCTGCGTGACCAGTGCCTGGCTGTCTGTGATGGTGTGCTGGGCGTCTTC
GCTCTCGATGACCCCTCGTCTCTGATCCAGCTGCAGCAGATATGGGCCACCTGGGGCCCT
CACCCCGCCCAGCCCCTTGTCCTCGTGGGCAACAAGTGTGACCTTGTGACCACTGCTGGA
GATGCTCATGCCGCTGCTGCAGCCCTCGCACACAGCTGGGGGGCCCACTTCGTGGAGACC
TCGGCCAAAACACGGCAAGGCGTGGAGGAGGCCTTTTCCCTGCTGGTCCATGAGATCCAG
AGGGTCCAGGAGGCCATGGCGAAGGAGCCCATGGCAAGGTCCTGTAGGGAGAAGACCCGG
CACCAGAAGGCCACCTGCCACTGTGGCTGCTCTGTGGCCTGA

Protein Properties

Number of Residues

233

Molecular Weight

25286.5

Theoretical pI

6.57

Pfam Domain Function

Ras (PF00071 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>GTPase ERas
MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQ
LNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVF
ALDDPSSLIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVET
SAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA

External Links

GenBank ID Protein

31158278

UniProtKB/Swiss-Prot ID

Q7Z444

UniProtKB/Swiss-Prot Entry Name

RASE_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB093575

GeneCard ID