Identification
HMDB Protein ID CDBP03732
Secondary Accession Numbers Not Available
Name Ran-specific GTPase-activating protein
Description Not Available
Synonyms
  1. Ran-binding protein 1
  2. RanBP1
Gene Name RANBP1
Protein Type Enzyme
Biological Properties
General Function Involved in intracellular transport
Specific Function Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane
GO Classification
Process
intracellular transport
establishment of localization
transport
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 22q11.21
SNPs RANBP1
Gene Sequence
>606 bp
ATGGCGGCCGCCAAGGACACTCATGAGGACCATGATACTTCCACTGAGAATACAGACGAG
TCCAACCATGACCCTCAGTTTGAGCCAATAGTTTCTCTTCCTGAGCAAGAAATTAAAACA
CTGGAAGAAGATGAAGAGGAACTTTTTAAAATGCGGGCAAAACTGTTCCGATTTGCCTCT
GAGAACGATCTCCCAGAATGGAAGGAGCGAGGCACTGGTGACGTCAAGCTCCTGAAGCAC
AAGGAGAAAGGGGCCATCCGCCTCCTCATGCGGAGGGACAAGACCCTGAAGATCTGTGCC
AACCACTACATCACGCCGATGATGGAGCTGAAGCCCAACGCAGGTAGCGACCGTGCCTGG
GTCTGGAACACCCACGCTGACTTCGCCGACGAGTGCCCCAAGCCAGAGCTGCTGGCCATC
CGCTTCCTGAATGCTGAGAATGCACAGAAATTCAAAACAAAGTTTGAAGAATGCAGGAAA
GAGATCGAAGAGAGAGAAAAGAAAGCAGGATCAGGCAAAAATGATCATGCCGAAAAAGTG
GCGGAAAAGCTAGAAGCTCTCTCGGTGAAGGAGGAGACCAAGGAGGATGCTGAGGAGAAG
CAATAA
Protein Properties
Number of Residues 201
Molecular Weight 23309.9
Theoretical pI 4.96
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Ran-specific GTPase-activating protein
MAAAKDTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFAS
ENDLPEWKERGTGDVKLLKHKEKGAIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAW
VWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREKKAGSGKNDHAEKV
AEKLEALSVKEETKEDAEEKQ
GenBank ID Protein 47678643
UniProtKB/Swiss-Prot ID P43487
UniProtKB/Swiss-Prot Entry Name RANG_HUMAN
PDB IDs
GenBank Gene ID CR456556
GeneCard ID RANBP1
GenAtlas ID RANBP1
HGNC ID HGNC:9847
References
General References Not Available