| Identification |
|---|
| HMDB Protein ID
| CDBP03732 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ran-specific GTPase-activating protein |
| Description
| Not Available |
| Synonyms
|
- Ran-binding protein 1
- RanBP1
|
| Gene Name
| RANBP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in intracellular transport |
| Specific Function
| Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane |
| GO Classification
|
| Process |
| intracellular transport |
| establishment of localization |
| transport |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 22q11.21 |
| SNPs
| RANBP1 |
| Gene Sequence
|
>606 bp
ATGGCGGCCGCCAAGGACACTCATGAGGACCATGATACTTCCACTGAGAATACAGACGAG
TCCAACCATGACCCTCAGTTTGAGCCAATAGTTTCTCTTCCTGAGCAAGAAATTAAAACA
CTGGAAGAAGATGAAGAGGAACTTTTTAAAATGCGGGCAAAACTGTTCCGATTTGCCTCT
GAGAACGATCTCCCAGAATGGAAGGAGCGAGGCACTGGTGACGTCAAGCTCCTGAAGCAC
AAGGAGAAAGGGGCCATCCGCCTCCTCATGCGGAGGGACAAGACCCTGAAGATCTGTGCC
AACCACTACATCACGCCGATGATGGAGCTGAAGCCCAACGCAGGTAGCGACCGTGCCTGG
GTCTGGAACACCCACGCTGACTTCGCCGACGAGTGCCCCAAGCCAGAGCTGCTGGCCATC
CGCTTCCTGAATGCTGAGAATGCACAGAAATTCAAAACAAAGTTTGAAGAATGCAGGAAA
GAGATCGAAGAGAGAGAAAAGAAAGCAGGATCAGGCAAAAATGATCATGCCGAAAAAGTG
GCGGAAAAGCTAGAAGCTCTCTCGGTGAAGGAGGAGACCAAGGAGGATGCTGAGGAGAAG
CAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 201 |
| Molecular Weight
| 23309.9 |
| Theoretical pI
| 4.96 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ran-specific GTPase-activating protein
MAAAKDTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFAS
ENDLPEWKERGTGDVKLLKHKEKGAIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAW
VWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREKKAGSGKNDHAEKV
AEKLEALSVKEETKEDAEEKQ
|
| External Links |
|---|
| GenBank ID Protein
| 47678643 |
| UniProtKB/Swiss-Prot ID
| P43487 |
| UniProtKB/Swiss-Prot Entry Name
| RANG_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| CR456556 |
| GeneCard ID
| RANBP1 |
| GenAtlas ID
| RANBP1 |
| HGNC ID
| HGNC:9847 |
| References |
|---|
| General References
| Not Available |