| Identification |
|---|
| HMDB Protein ID
| CDBP03729 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ras-interacting protein 1 |
| Description
| Not Available |
| Synonyms
|
- Rain
|
| Gene Name
| RASIP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transduction |
| Specific Function
| May act as effector for Golgi-bound HRAS and other Ras- like proteins. May promote HRAS-mediated transformation |
| GO Classification
|
| Process |
| signal transduction |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
|
| Cellular Location
|
- Cytoplasm
- perinuclear region
- Golgi apparatus
- Golgi stack
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.33 |
| SNPs
| RASIP1 |
| Gene Sequence
|
>2892 bp
ATGCTGTCTGGTGAACGGAAGGAGGGCGGAAGCCCCCGCTTCGGGAAGCTTCATCTCCCC
GTGGGCCTGTGGATCAATTCCCCCAGGAAGCAGCTGGCGAAGCTGGGGCGGCGCTGGCCC
AGCGCAGCCTCTGTCAAGTCTTCTTCGTCGGACACGGGGAGCCGCAGCAGCGAGCCGCTA
CCTCCGCCCCCGCCGCACGTGGAGCTGCGGCGAGTGGGCGCTGTCAAGGCGGCCGGGGGA
GCCTCCGGTAGCCGCGCCAAGCGCATCTCCCAGCTCTTCCGGGGCTCGGGGACCGGGACC
ACGGGGTCCAGCGGCGCAGGAGGCCCTGGGACCCCGGGGGGCGCGCAGCGCTGGGCCAGC
GAGAAGAAGCTGCCGGAGCTGGCGGCGGGCGTGGCCCCCGAGCCCCCGCTGGCTACCCGC
GCCACGGCGCCTCCGGGGGTCCTCAAGATCTTCGGCGCCGGACTGGCATCGGGCGCCAAC
TACAAGAGCGTGCTGGCCACGGCGCGCTCCACGGCGCGCGAGCTCGTGGCCGAGGCGCTA
GAGCGCTACGGCCTAGCAGGCAGCCCCGGCGGTGGCCCCGGCGAGAGCAGCTGCGTGGAC
GCCTTCGCTTTGTGCGACGCTCTGGGCCGGCCCGCGGCGGCGGGCGTGGGAAGCGGCGAG
TGGCGGGCGGAGCACCTGCGCGTGCTGGGCGACTCCGAGCGCCCGCTGCTGGTGCAGGAG
CTGTGGCGGGCGCGGCCCGGCTGGGCGCGGCGCTTCGAGTTGCGCGGCCGCGAGGAGGCG
CGGCGCCTGGAGCAGGAGGCCTTCGGGGCCGCGGACAGCGAAGGCACCGGCGCCCCTTCG
TGGCGGCCACAGAAGAACCGCTCCCGGGCGGCGTCGGGTGGGGCAGCGCTGGCCAGTCCT
GGCCCGGGGACCGGATCAGGGGCCCCAGCTGGGTCTGGAGGCAAGGAGCGCTCAGAAAAC
TTGTCTTTGCGGCGCAGCGTGTCGGAGCTTAGCCTTCAGGGGCGGCGGCGGCGGCAGCAG
GAGCGGAGACAGCAGGCACTTAGCATGGCCCCAGGGGCAGCCGACGCCCAAATCGGAACT
GCAGACCCCGGGGACTTCGATCAGTTGACTCAGTGCCTCATCCAGGCCCCCAGCAACCGC
CCCTACTTCCTGCTGCTCCAGGGCTACCAGGACGCCCAGGACTTTGTGGTGTATGTGATG
ACGCGAGAGCAGCACGTGTTTGGGCGAGGTGGGAACTCGTCTGGCCGCGGGGGGTCCCCG
GCTCCCTATGTGGACACCTTCCTCAACGCCCCGGACATCCTGCCGCGTCACTGCACAGTG
CGCGCGGGCCCTGAGCACCCGGCCATGGTGCGCCCGTCCCGGGGCGCCCCAGTCACGCAC
AACGGGTGCCTCCTGCTGCGGGAGGCTGAGCTGCACCCGGGCGACCTCCTGGGGCTGGGC
GAGCACTTCCTGTTCATGTACAAGGACCCCCGCACTGGGGGCTCGGGGCCTGCGAGGCCG
CCGTGGCTGCCCGCGCGCCCCGGGGCCACGCCGCCAGGCCCTGGCTGGGCCTTCTCCTGT
CGCCTGTGCGGCCGCGGCCTGCAGGAGCGCGGCGAGGCACTGGCCGCCTACCTGGACGGC
CGTGAGCCAGTCCTGCGCTTCCGGCCGCGCGAGGAGGAGGCGCTGCTGGGCGAGATCGTG
CGCGCCGCAGCCGCCGGCTCGGGAGACCTGCCGCCCCTCGGGCCCGCCACGCTGCTGGCG
CTGTGCGTGCAGCATTCCGCCCGTGAGCTGGAGCTGGGCCACCTGCCACGACTGCTGGGC
CGCCTGGCCCGGCTCATCAAGGAGGCCGTCTGGGAAAAGATTAAGGAAATTGGAGACCGT
CAGCCAGAAAACCACCCTGAGGGGGTCCCCGAGGTGCCCCTGACTCCTGAAGCTGTGTCT
GTGGAGCTGCGGCCACTCATGCTGTGGATGGCCAACACCACGGAGCTGCTTAGCTTTGTG
CAGGAGAAGGTGCTGGAAATGGAGAAGGAGGCTGACCAAGAGGACCCACAGCTCTGCAAT
GACTTGGAATTATGTGATGAGGCCATGGCCCTCCTGGATGAGGTCATCATGTGTACCTTC
CAGCAGTCTGTCTACTACCTCACCAAGACTCTCTATTCAACGCTGCCTGCTCTCCTGGAT
AGTAACCCTTTCACAGCTGGTGCAGAGCTGCCGGGGCCTGGCGCGGAGCTGGGGGCCATG
CCTCCAGGATTGAGACCTACCCTGGGCGTGTTCCAGGCAGCCTTGGAGCTGACCAGCCAG
TGCGAGCTGCACCCTGACCTCGTGTCTCAGACTTTTGGCTACTTGTTCTTCTTCTCCAAC
GCATCCCTTCTCAACTCGCTGATGGAACGAGGTCAAGGCCGGCCTTTCTATCAATGGTCC
CGAGCTGTTCAAATCCGAACCAACCTGGACCTCGTCTTGGACTGGCTACAGGGAGCTGGG
CTGGGCGACATTGCCACTGAGTTCTTCCGGAAACTCTCCATGGCTGTGAACCTGCTCTGT
GTGCCCCGCACTTCCCTGCTCAAGGCTTCATGGAGCAGCCTAAGAACCGACCACCCCACC
TTGACCCCCGCCCAGCTGCACCATCTGCTCAGCCACTATCAGCTGGGCCCTGGCCGCGGG
CCGCCAGCCGCGTGGGACCCTCCCCCTGCAGAGCGGGAGGCTGTGGACACAGGGGACATC
TTCGAAAGCTTCTCCTCGCACCCGCCCCTCATCCTCCCCCTGGGGAGCTCGCGCCTGCGC
CTCACTGGTCCAGTGACGGACGATGCCTTGCACCGTGAACTCCGTAGGCTCCGCCGCCTC
CTCTGGGATCTTGAGCAGCAGGAGCTGCCAGCCAATTATCGCCATGGGCCTCCCGTGGCC
ACGTCTCCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 963 |
| Molecular Weight
| 103456.3 |
| Theoretical pI
| 8.02 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ras-interacting protein 1
MLSGERKEGGSPRFGKLHLPVGLWINSPRKQLAKLGRRWPSAASVKSSSSDTGSRSSEPL
PPPPPHVELRRVGAVKAAGGASGSRAKRISQLFRGSGTGTTGSSGAGGPGTPGGAQRWAS
EKKLPELAAGVAPEPPLATRATAPPGVLKIFGAGLASGANYKSVLATARSTARELVAEAL
ERYGLAGSPGGGPGESSCVDAFALCDALGRPAAAGVGSGEWRAEHLRVLGDSERPLLVQE
LWRARPGWARRFELRGREEARRLEQEAFGAADSEGTGAPSWRPQKNRSRAASGGAALASP
GPGTGSGAPAGSGGKERSENLSLRRSVSELSLQGRRRRQQERRQQALSMAPGAADAQIGT
ADPGDFDQLTQCLIQAPSNRPYFLLLQGYQDAQDFVVYVMTREQHVFGRGGNSSGRGGSP
APYVDTFLNAPDILPRHCTVRAGPEHPAMVRPSRGAPVTHNGCLLLREAELHPGDLLGLG
EHFLFMYKDPRTGGSGPARPPWLPARPGATPPGPGWAFSCRLCGRGLQERGEALAAYLDG
REPVLRFRPREEEALLGEIVRAAAAGSGDLPPLGPATLLALCVQHSARELELGHLPRLLG
RLARLIKEAVWEKIKEIGDRQPENHPEGVPEVPLTPEAVSVELRPLMLWMANTTELLSFV
QEKVLEMEKEADQEDPQLCNDLELCDEAMALLDEVIMCTFQQSVYYLTKTLYSTLPALLD
SNPFTAGAELPGPGAELGAMPPGLRPTLGVFQAALELTSQCELHPDLVSQTFGYLFFFSN
ASLLNSLMERGQGRPFYQWSRAVQIRTNLDLVLDWLQGAGLGDIATEFFRKLSMAVNLLC
VPRTSLLKASWSSLRTDHPTLTPAQLHHLLSHYQLGPGRGPPAAWDPPPAEREAVDTGDI
FESFSSHPPLILPLGSSRLRLTGPVTDDALHRELRRLRRLLWDLEQQELPANYRHGPPVA
TSP
|
| External Links |
|---|
| GenBank ID Protein
| 38570105 |
| UniProtKB/Swiss-Prot ID
| Q5U651 |
| UniProtKB/Swiss-Prot Entry Name
| RAIN_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_017805.2 |
| GeneCard ID
| RASIP1 |
| GenAtlas ID
| RASIP1 |
| HGNC ID
| HGNC:24716 |
| References |
|---|
| General References
| Not Available |