Identification
HMDB Protein ID CDBP03723
Secondary Accession Numbers Not Available
Name Ras-related protein Rab-5B
Description Not Available
Synonyms Not Available
Gene Name RAB5B
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function Protein transport. Probably involved in vesicular traffic
GO Classification
Function
gtp binding
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
Process
establishment of localization
transport
protein transport
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Lipid-anchor
  4. Melanosome
  5. Cytoplasmic side
  6. Early endosome membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q13
SNPs RAB5B
Gene Sequence
>648 bp
ATGACTAGCAGAAGCACAGCTAGGCCCAATGGGCAACCCCAGGCCAGCAAAATTTGCCAG
TTCAAATTGGTCCTGCTGGGAGAATCTGCAGTGGGAAAGTCAAGCCTGGTATTACGTTTT
GTCAAAGGGCAGTTCCATGAGTACCAGGAGAGCACCATTGGAGCGGCCTTCCTCACCCAG
TCCGTTTGTCTAGATGACACAACAGTGAAGTTTGAGATCTGGGACACAGCTGGGCAGGAG
CGATATCACAGCTTAGCCCCCATGTACTACAGGGGTGCCCAAGCTGCAATCGTGGTTTAC
GACATTACTAATCAGGAAACCTTTGCCCGAGCAAAGACATGGGTGAAGGAACTACAGCGA
CAGGCCAGTCCTAGCATCGTTATTGCCCTGGCAGGGAACAAAGCTGACCTGGCCAACAAA
CGTATGGTGGAGTATGAAGAGGCCCAGGCATATGCAGATGACAACAGCTTATTGTTCATG
GAGACTTCAGCCAAGACAGCTATGAACGTGAATGATCTCTTCCTGGCAATAGCTAAGAAG
TTGCCAAAGAGTGAACCCCAGAATCTGGGAGGTGCAGCAGGCCGAAGCCGGGGTGTGGAT
CTCCATGAACAGTCCCAGCAGAACAAGAGCCAGTGTTGTAGCAACTGA
Protein Properties
Number of Residues 215
Molecular Weight 23706.6
Theoretical pI 8.3
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Ras-related protein Rab-5B
MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQ
SVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQR
QASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKK
LPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN
GenBank ID Protein 20379050
UniProtKB/Swiss-Prot ID P61020
UniProtKB/Swiss-Prot Entry Name RAB5B_HUMAN
PDB IDs
GenBank Gene ID AF498937
GeneCard ID RAB5B
GenAtlas ID RAB5B
HGNC ID HGNC:9784
References
General References Not Available